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Related: Editorials & Other Articles, Issue Forums, Alliance Forums, Region ForumsOne of Big Pharma's Most Disastrous Drugs Destroyed This Man's Spine
Merck was aware of a popular drug's impact on bones but still pushed it on doctors and patients.It has been a decade since Merck's "super-aspirin" Vioxx was withdrawn from the market after a study showed it doubled the risk of heart attacks and strokes. Heavily advertised by celebrity athletes like Dorothy Hamill and Bruce Jenner and used by approximately 20 million patients, estimates of the heart attacks caused by Vioxx range from 27,000 to up to 140,000. The Vioxx scandal made Merck the poster child for deceptive marketing because the cardiovascular risk data was deliberately withheld from the FDA, medical journals and the drug-taking public and their doctors, according to news reports. In 2010, Merck compensated 20,591 heart attack and 12,447 stroke plaintiffs out of a $4.85 billion settlement fund.
Now, in an improbable chain of events, Merck is returning to court against its will to face charges that Vioxx also caused devastating non-healing of spine/bone after surgical procedures, a charge supported by scientific studies. The suit is brought by Dennis Harrison, one of few plaintiffs remaining from the 70,000-case multidistrict litigation (MDL) that led to Merck's 2007 settlement. Unlike patients prescribed Vioxx for its FDA-approved uses of osteoarthritis, menstrual pain and acute pain, Harrison was prescribed Vioxx for the unapproved use of rheumatoid arthritis (RA). In 2011, Merck also settled charges that it "misbranded" Vioxx by promoting it for RA, illegal marketing that made RA the fifth most common reason for Vioxx use.
Because RA was an unapproved Vioxx use and Merck is not shielded by FDA approval, the suit claims outright fraud. "It is no different than if Merck sold the drug on a street corner," Jim Duggan, who has been providing legal support to Harrison, told me in a phone interview. A summary judgment filed by Merck (a legal move that says the case is without merit and does not need to be tried) was denied in May and Merck must go to court in New York.
Harrison, 61, a former product planner and business strategist with ATT/Lucent Technologies, sustained permanent spinal damage from years of high doses of Vioxx, according to court filings, when his body failed to form bone after a 2001 spinal fusion operation. He spent months in a nursing home unable to walk, endured sepsis and other life-threatening conditions and is largely bedridden to this day. Nearly all of his doctors attended Merck-funded seminars to build confidence in Vioxx, claims Harrison, and were not told about its serious bone effects. "Merck knew and the doctors and public didn't," says Harrison.
http://www.alternet.org/personal-health/one-big-pharmas-most-disastrous-drugs-destroyed-mans-spine
pnwmom
(108,976 posts)There weren't any approved studies showing that this drug was safe and effective for RA sufferers, yet Merck marketed it to their doctors anyway.
sakabatou
(42,146 posts)It's just really bad medicine.
pnwmom
(108,976 posts)MattBaggins
(7,904 posts)Jesus Malverde
(10,274 posts)Jesus
Orrex
(63,203 posts)Last edited Mon Jun 9, 2014, 08:51 AM - Edit history (1)
"Woo-ness" isn't determined by whether or not a treatment works; it's determined by whether or not the advocates & users of a product/procedure claim that it works according to magical or psedoscientific means.
If Merck engaged in fraud, it should certainly face criminal penalties. If a proponent of woo engages in fraud, then that proponent should certainly face criminal penalties as well.
Why do you believe that this case is woo, other than because it bolsters your faith in pseudoscience and your distrust/misunderstanding of actual science and medicine?
pnwmom
(108,976 posts)the treatment has been proven with repeated scientific studies to work.
There were no approved scientific studies on the use of VIOXX for RA patients. Its use was as much "woo" as any unproven treatment.
Orrex
(63,203 posts)If an assertion is consistent with and does not contradict established science but is ultimately shown to be incorrect, then the asserton can be wrong and it can be fraudulent, but it need not be woo.
I don't know why you're arguing this point, either, because even if we accept your notion, you're simply linking woo-in-general to the criminally bad of a particular company. Why would you seek such an alliance?
Incidentally, were the negative side effect of Vioxx identified through science or through woo? Can you point to even one instance when pseudoscience was used to show that some other kind of pseudoscience was shown to be fraudulent?
pnwmom
(108,976 posts)Orrex
(63,203 posts)I would be interested to read your complaints about such pseudoscience as the "supplement" industry or "therapeutic touch" and similar forms of "energy" healing.
That is, I don't recall ever seeing you come out against any of those forms of woo; instead, you focus your attention on the occasional bad practice of actual science or actual medicine.
Your consistency in this regard suggests, even if you're not a woo supporter, you are curiously specific in selecting your targets.
classykaren
(769 posts)Remember before Ronald Regan, when the FDA did it's own drug testing and did not depend on data from the drug manufacturers ?
sendero
(28,552 posts)... "medical science" said this drug was safe. Nothing to see here.
BainsBane
(53,031 posts)Obviously it wasn't safe, but the reason for the recall was that it contributed to heart problems.
DeSwiss
(27,137 posts)...would be, if anyone were surprised.
- K&R
FDA lets drugs approved on fraudulent research stay on market
MannyGoldstein
(34,589 posts)FDA's own figures.
hunter
(38,310 posts)Opiates, cannabis, any other number of drugs would have been less dangerous.
But OH NO! Effective drugs with less dangerous side effects are EVIL!
The perfect Pharmaceutical company pain killer would kill the pain but it would never let you forget you were still broken person, maybe it would put a big scarlet D for "druggie" on your face because that's some vengeful puritanical god's plan or something.
Our society is sick, and there are too many profiting from this sickness. Corporations (Merck) and institutions (the DEA) will lie, cheat, and steal to keep those drug profits flowing.