2. House legislative activity will cease. Again, there wasn't a heck of a lot of grand legislative plans before Cantor's loss. But that trickle will totally dry up now as Republican members avoid doing anything -- literally, anything -- that could be used against them in the many primaries still to come this summer and fall. Members will be afraid of their own shadows.

3. The "establishment strikes back" storyline will disappear. In the space of the last week, the narrative that the establishment has finally figured out how to beat the tea party has exploded. First, Mississippi state Sen. Chris McDaniel finished ahead of Sen. Thad Cochran in the state's GOP primary. Now, the Cantor loss. (And, on June 24, Cochran remains an underdog to McDaniel in the Magnolia State runoff.) A former Senate Appropriations Committee chairman and the second-ranking Republican in the House both (potentially) losing in less than a month means that the primary victories of Sens. John Cornyn (R-Tex.) and Mitch McConnell (R-Ky.) over tea party-backed opponents earlier this year will be forgotten -- or, at the very least, overshadowed.

4. Tea party challenges will surge. David Brat -- and McDaniel if he wins -- will become the newest tea party heroes, taking their places alongside the likes of Sens. Ted Cruz (Tex.) and Mike Lee (Utah). In the near term, that will embolden tea partyers who seemed dead in the water in their own attempts to take out incumbents. "What we have seen tonight in Virginia shows that no race should be taken for granted and all the money and position in the world doesn't resonate with an electorate that is fed up with a Washington establishment that has abandoned conservative principles," said Joe Carr, a conservative trying to knock off Sen. Lamar Alexander (R) in Tennessee. (To be clear: Attempting to ride the Brat coattails with a press release is one thing. Beating an incumbent like Alexander is something totally different.) In the longer term, there's every reason to believe that other prominent members of the GOP leadership -- in the House and Senate -- will face tea party challenges come 2016.

5. The race to replace John Boehner as speaker is now wide open. We've written before about how difficult it will be for Boehner to hold on to his speakership -- assuming Republicans keep the majority this fall. But now the heir apparent has been dragged under by a conservative uprising. The third man in command -- House Majority Whip Kevin McCarthy (Calif.) -- is not exactly a tea party darling or, stylistically speaking, the sort of hard-liner that the most conservative wing in the House likes. Add it all up and you are looking at what could be an absolutely bananas race to lead the House Republican majority come 2015.