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Sgent

(5,857 posts)
Tue Oct 6, 2015, 08:54 AM Oct 2015

How a secret Chinese military drug based on an ancient herb won the Nobel Prize

Nearly 50 years ago, Tu Youyou began working on a classified Communist military project using clues from ancient Chinese medicine in search of new cures for malaria.

Today, Tu shared the Nobel Prize for Medicine in recognition of her work, which has led to one of the world’s final and most potent defenses against a tropical disease that kills over half a million people each year.

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They found a reference in a third-century text from Chinese physician Ge Hong. To cure “intermittent fevers,” the recipe called for soaking the qinghao plant in water, wringing it out, and drinking the juice — as opposed to boiling it in a tea.

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Demand quickly grew. Drugs that contain artemisinin or its sister compounds are special not only because they wipe out malaria quickly, but also because they attack the parasite in a new, unique way. By the early 2000s, multi-drug resistant strains of malaria were spreading in several regions of the world. Artemisinin became the one of last lines of defense, and the World Health Organization ramped up efforts to provide the drug.

http://www.washingtonpost.com/news/wonkblog/wp/2015/10/06/how-a-secret-chinese-military-drug-based-on-an-ancient-herb-won-the-nobel-prize/

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How a secret Chinese military drug based on an ancient herb won the Nobel Prize (Original Post) Sgent Oct 2015 OP
My dad got malaria while fighting in the Pacific Theater in WWII Omaha Steve Oct 2015 #1
A Chinese herb? world wide wally Oct 2015 #2
Sure, because no modern drugs are derived from natural ingredients Major Nikon Oct 2015 #3
Yeah, woo, like willow bark extract PADemD Oct 2015 #4
This went through slightly more testing than "it REALLY works!" NuclearDem Oct 2015 #5
How about comfrey? Coca-Cola? Opiates? Marijuana? mhatrw Oct 2015 #9
Funny! snort Oct 2015 #8
thank you niyad Oct 2015 #6
Dr. Keith Arnold on NPR yesterday... Nitram Oct 2015 #7

PADemD

(4,482 posts)
4. Yeah, woo, like willow bark extract
Tue Oct 6, 2015, 11:32 AM
Oct 2015

Medicines made from willow and other salicylate-rich plants appear in Egyptian pharonic pharmacology papyri [1] from the second millennium BCE. Hippocrates referred to their use of salicylic tea to reduce fevers around 400 BCE[citation needed], and were part of the pharmacopoeia of Western medicine in classical antiquity and the Middle Ages. Willow bark extract became recognized for its specific effects on fever, pain and inflammation in the mid-eighteenth century. Lewis and Clark allegedly used willow bark tea in 1803–1806 as a remedy for fever for members of the famous expedition. By the nineteenth century pharmacists were experimenting with and prescribing a variety of chemicals related to salicylic acid, the active component of willow extract.

https://en.wikipedia.org/wiki/History_of_aspirin

 

NuclearDem

(16,184 posts)
5. This went through slightly more testing than "it REALLY works!"
Tue Oct 6, 2015, 11:37 AM
Oct 2015

That willow tree bark has medicinal benefits doesn't mean Venus fly trap extract cures cancer.

mhatrw

(10,786 posts)
9. How about comfrey? Coca-Cola? Opiates? Marijuana?
Tue Oct 6, 2015, 04:40 PM
Oct 2015

Most modern Western medicines are synthesized concentrates of botanical chemicals.

Often the whole herb is superior because of synergistic botanicals. All of Chinese medicine is based on this. And Chinese doctors seem to have billions of satisfied woo-worshiping patents.

Nitram

(22,776 posts)
7. Dr. Keith Arnold on NPR yesterday...
Tue Oct 6, 2015, 11:54 AM
Oct 2015

...says Tu Youyou was not the main person involved in development of the drug.

"The Lasker committee named her “the discoverer of artemisinin.” Some Chinese and Western malariologists were outraged. Dr. Nicholas J. White, a prominent Oxford malaria researcher, said it was “not fair to credit this discovery to one individual”; he named others he considered equally deserving, including the clinical trial leader, Dr. Li, and a chemist, Li Ying."

http://www.nytimes.com/2012/01/17/health/for-intrigue-malaria-drug-artemisinin-gets-the-prize.html

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