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n2doc

(47,953 posts)
Thu Aug 25, 2016, 11:46 AM Aug 2016

Scientists have finally figured out how cancer spreads through the bloodstream

DAVID NIELD

In what could be a major step forward in our understanding of how cancer moves around the body, researchers have observed the spread of cancer cells from the initial tumour to the bloodstream.

The findings suggest that secondary growths called metastases 'punch' their way through the walls of small blood vessels by targeting a molecule known as Death Receptor 6 (no, really, that's what it's called). This then sets off a self-destruct process in the blood vessels, allowing the cancer to spread.

According to the team from Goethe University Frankfurt and the Max Planck Institute in Germany, disabling Death Receptor 6 (DR6) may effectively block the spread of cancerous cells - so long as there aren't alternative ways for the cancer to access the bloodstream.

"This mechanism could be a promising starting point for treatments to prevent the formation of metastases," said lead researcher Stefan Offermanns.

more
http://www.sciencealert.com/scientists-discover-how-cancer-spreads-through-the-bloodstream

19 replies = new reply since forum marked as read
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Scientists have finally figured out how cancer spreads through the bloodstream (Original Post) n2doc Aug 2016 OP
thanks for posting. n/t eShirl Aug 2016 #1
I am no scientist, but this looks like HUGE news to me. rurallib Aug 2016 #2
Me, too. hamsterjill Aug 2016 #6
They do seem to come and go PatSeg Aug 2016 #9
There are a lot of cancers knightmaar Aug 2016 #10
That's a good point PatSeg Aug 2016 #13
That fact is often overlooked by many people True Dough Aug 2016 #17
Yes, that is my concern, as well. hamsterjill Aug 2016 #12
I could be more optimistic PatSeg Aug 2016 #14
KnR! Hekate Aug 2016 #3
Hope hibbing Aug 2016 #4
Great News! And great band name! Death Receptor Six Rock Coachella! n/t station agent Aug 2016 #5
I've been a DRS fan for years lame54 Aug 2016 #7
I was a fan before the rest of you and now I think they are sellouts. :) nt TeamPooka Aug 2016 #8
You win! 7962 Aug 2016 #11
Have you heard their latest ? GeorgeGist Aug 2016 #15
Yeah, more like Death Receptor Sucks. nt TeamPooka Aug 2016 #16
Cross your fingers! jimlup Aug 2016 #18
We have to remember that nature is convservative question everything Aug 2016 #19

hamsterjill

(15,220 posts)
6. Me, too.
Thu Aug 25, 2016, 01:01 PM
Aug 2016

But somehow, these "breakthroughs" that we hear about many times don't seem to have a large impact, or at least I don't hear about that. Maybe I'm just out of touch.

I sincerely hope this IS one of those times when it is indeed huge, and that the scientists have the funding, etc. to fully investigate their findings and implement protocols to save more stricken patients.

PatSeg

(47,277 posts)
9. They do seem to come and go
Thu Aug 25, 2016, 02:17 PM
Aug 2016

I wonder if some of that could be because of the pharmaceutical industry. There's a lot of money in "cancer".

knightmaar

(748 posts)
10. There are a lot of cancers
Thu Aug 25, 2016, 02:25 PM
Aug 2016

So when you see "the" cure for cancer, you know it's a misunderstanding. It should be *a* cure for *a* particular cancer.

In this case, this may prevent the spread of cancer through the bloodstream and will matter to cancers that spread through the bloodstream, assuming there's no other receptor through which they can spread. You'd still have to deal with the original cancer, though.

PatSeg

(47,277 posts)
13. That's a good point
Thu Aug 25, 2016, 02:41 PM
Aug 2016

"A cure for cancer" makes a nice bumper sticker, but it is truly an oversimplification.

This could possibly be part of the treatment for some forms of cancer.

True Dough

(17,255 posts)
17. That fact is often overlooked by many people
Fri Aug 26, 2016, 02:08 AM
Aug 2016

They think of cancer as this homogeneous disease that attacks different parts of the body. Not so.

hamsterjill

(15,220 posts)
12. Yes, that is my concern, as well.
Thu Aug 25, 2016, 02:28 PM
Aug 2016

I keep hearing of wonderful steps forward, but then I don't hear of those steps actually being implemented.

Again, I may be simply unaware, but I would think we'd be reading more in mainstream media.

jimlup

(7,968 posts)
18. Cross your fingers!
Fri Aug 26, 2016, 09:54 AM
Aug 2016

Hoping that this is the key. My son-in-law is currently fighting this disease and may win but a little help from science would certainly go a long way!

question everything

(47,436 posts)
19. We have to remember that nature is convservative
Fri Aug 26, 2016, 11:44 AM
Aug 2016

that usually there is more than one function for a specific molecule.

Thus, before one kills this one, one has to be sure what else would be deactivated, or activated.

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