Ancient DNA reveals staying power of early people of the Andes

By Elizabeth Pennisi
May. 7, 2020 , 12:00 PM



Machu Picchu was built by the Incas, one of several cultures that settled in the Central Andes over thousands of years. MATTHEW BUTCHER

Ancient DNA reveals staying power of early people of the Andes
By Elizabeth PennisiMay. 7, 2020 , 12:00 PM

Some of the world’s more famous and closely examined archaeological sites pepper the hillsides of the Central Andes, documenting an invention of farming and the rise and fall of powerful civilizations such as the Inca. Now, the largest study of ancient human genomes in South America has added a personal touch to the artifacts. The new research reveals who lived there, when they lived, and how they moved around and intermingled. And despite being a heavily studied area, a big surprise emerged: Descendants of early inhabitants persisted even as civilizations came and went.

“This paper sheds light on a region that’s home to some of the world’s most intensively studied ancient societies during a particularly dynamic period in its history,” says Jennifer Raff, an anthropological geneticist at the University of Kansas, Lawrence, who was not involved in the work. “Now, we are beginning to understand the biological history as well” as the archaeological history.

The Central Andes Mountains, located mostly in today’s Peru, includes coastal and highland regions. The Incas are the most well-known of the ancient civilizations to live there: During their 100-year reign, until the Spanish conquered them in the mid-1500s, they built an extensive road system and constructed magnificent stone structures, such as Machu Picchu. And they were preceded by several other well-developed societies. The Moche lived there from 200 C.E. to 850 C.E. and are known for having built giant adobe mounds with murals inside. Overlapping partially in time were the Wari, known for fine textiles and terraced agriculture. And there were other groups as well, such as the Nasca and Tiwanaku.

Researchers from Harvard University and other institutions had already sequenced DNA from 9000-year-old human remains from the Central Andes highlands as part of a broad survey of dozens of South American ancient DNA samples. To get a more comprehensive look at the genetic history of the region, teams led by Harvard population geneticist David Reich and Lars Fehren-Schmitz, a paleogenomicist at the University of California, Santa Cruz, joined with South American colleagues and worked with local authorities to get DNA from many key archaeological sites, sequencing 64 new ancient genomes. Using radiocarbon dating, they determined the DNA belonged to people who lived between 9000 to 500 years ago. The researchers compared those genomes with each other and 25 already sequenced ancient samples.

More:
https://www.sciencemag.org/news/2020/05/ancient-dna-reveals-staying-power-early-people-andes#