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Cervical cancer vaccine a success, says Lancet report

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kpete Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Jun-17-11 05:45 PM
Original message
Cervical cancer vaccine a success, says Lancet report
Edited on Fri Jun-17-11 05:45 PM by kpete
Source: Guardian UK

Cervical cancer vaccine a success, says Lancet report
Australian study of injection to protect against HPV virus reveals drop in high-grade abnormalities among under-18s

Sarah Boseley, health editor
The Guardian, Friday 17 June 2011


The first evidence has emerged that nationwide vaccination programmes for young women against HPV, the virus that triggers cervical cancer, are likely to cut the numbers who get the disease.

A study in Australia, one of the first countries to introduce the vaccination, has shown a drop in high-grade cervical abnormalities – changes to the cells in the neck of the womb that can be the precursor to cancer.

Australia introduced nationwide HPV (human papilloma virus) vaccination for women aged 12 to 26 from 2007.

While it will take many years to find out whether vaccination programmes definitely reduce the numbers of cervical cancers in the population, Australian scientists were able to analyse the results from their screening programme to find out whether there has been any drop in the number of young women with abnormal cell changes that are the precursor of cancer.


Read more: http://www.guardian.co.uk/society/2011/jun/17/cervical-cancer-vaccine-success-lancet
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still_one Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Jun-17-11 05:48 PM
Response to Original message
1. I have no doubt the anti-vaccine/anti-science folks will say this is inconclusive /nt
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Gormy Cuss Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Jun-19-11 11:52 AM
Response to Reply #1
9. The science folks are saying that, so if the anti-vaxxers say it too they're in good company.
While the study has a very promising finding, it's far from conclusive. From the linked article:

"The not-so-cautious optimist in us wants to hail this early finding as true evidence of vaccine effect," write Dr Mona Saraiya and Dr Susan Hariri of the Centres for Disease Control and Prevention in Atlanta, US, in a linked commentary for the journal.

But they said they wanted to know more about the vaccine status of the individuals (each woman is supposed to have three shots) and wanted more work to establish whether the reductions in potential cancers were really a result of vaccination or some other cause.

Michael Quinn, professor of gynaecology and gynaecologic oncology at the University of Melbourne, said: "The study is the first anywhere in the world to show falling rates of high-grade change in very young women.

"Although this is likely to be due to the effects of the vaccination programme, further analysis of information linking women's smear history to their vaccination history will be needed to prove that the fall is entirely due to vaccination rather than other factors."


Unfortunately Saraiya & Hariri's full commentary is behind the pay wall at the Lancet.

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Confusious Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Jun-17-11 06:04 PM
Response to Original message
2. just wait until they get autism
or the heartbreak of flatulence from this vaccine.
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kestrel91316 Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Jun-17-11 06:49 PM
Response to Reply #2
4. Oh, anti-vaxers' heads already exploded because some shrinking violets
fainted when they got the shot. They called it a terrible, dangerous side effect.

As a lifelong squeamish, needle-phobic fainter, that cracked me up.
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KittyWampus Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Jun-17-11 06:25 PM
Response to Original message
3. The article linked to gives absolutely no numbers. How many participated etc.
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tammywammy Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Jun-18-11 09:49 PM
Response to Reply #3
8. Lancet link
http://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(11)70145-0/fulltext

You can read the summary of the article there.

"Findings
In 315 061 women negative by HPV testing, the 5-year cumulative incidence of cancer was 3·8 per 100 000 women per year, slightly higher than for the 306 969 who were both negative by HPV and Pap testing (3·2 per 100 000), and half the cancer risk of the 319 177 who were negative by Pap testing (7·5 per 100 000). 313 465 (99·5%) women negative by HPV testing had either normal cytology or equivocal abnormalities. Abnormal cytology greatly increased cumulative incidence of CIN3 or worse over 5 years for the 16 757 positive by HPV testing (12·1% vs 5·9%; p<0·0001). By contrast, although statistically significant, abnormal cytology did not increase 5-year risk of CIN3 or worse for women negative by HPV testing to a substantial level (0·86% vs 0·16%; p=0·004). 12 208 (73%) of the women positive by HPV testing had no cytological abnormality, and these women had 258 (35%) of 747 CIN3 or worse, 25 (29%) of 87 cancers, and 17 (63%) of 27 adenocarcinomas."
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Odin2005 Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Jun-17-11 07:25 PM
Response to Original message
5. Hey Anti-Vaxers: EAT CROW.
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Viva_La_Revolution Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Jun-17-11 09:19 PM
Response to Original message
6. big K and R from this survivor. nt
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Sen. Walter Sobchak Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Jun-18-11 05:10 PM
Response to Original message
7. I couldn't feel more strongly about this,
Two women in my family have suffered from cervical cancer, one had been a full throttle Haight-Ashbury hippie and the other was a virgin on her wedding day and contracted HPV from her husband who attempted suicide over it.

All the young women in my family received Gardasil more or less immediately, and to the vaxxers all I can say is "Yes, I trust big-pharma more than the men they will fuck."
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