Short answer to the question: no.
If you had a Canadian-citizen parent, you might have Canadian citizenship. That, and being born in Canada, are the only way to acquire citizenship by birth.
It is also unlikely that many USAmericans have any family in Canada who could assist them in immigrating. Basically, to be "sponsored", one must be young and dependent, if the sponsor is a parent, or have an adult child or grandchild here.
Other relations -- parents of adult children, aunts, uncles, cousins -- really don't help much, unless the would-be immigrant already qualifies in terms of job skills.
Yer average Canadian doesn't know much more about immigrating to Canada than yer average USAmerican knows about immigrating to the US. I happen to know quite a lot, having worked in the field, but I've been out of the loop for a few years and am not in a position to answer specific questions any more.
USAmericans seriously wanting to find out their prospects need to start by going to
http://www.cic.gc.ca/english/index.html(You'll see a notice there about strike activity. Yes, Cdn federal public servants are entitled to strike, and do so from time to time. There were rotating strikes last month, and at present a ratification vote is being held on the employer's proposal, which I believe union leadership recommended that the members reject:
http://www.psac.com/home-e.shtml And oh yay; we may have another postal strike for Xmas ...)
The "Skilled Workers" link on that page at the CIC site (Citizenship and Immigration Canada) will provide all the basic information you need to assess your immigration potential.
If someone who has done that thinks s/he qualifies, and is serious and ready to start paying money, wants to contact me by PM, I could probably provide referrals to lawyers in Canada; having an application checked over first is probably a good investment.
The net can also be used to find immigration lawyers in Canada. The bar is much smaller here than in the US, and if you find a lawyer at a site where s/he is associated with Canadian Bar Association immigration law activities, or Law Union activities (similar to National Lawyers Guild), or other professional organizations or activities, you're probably quite safe. Big-name immigration lawyers will have cheaper, reliable juniors in their firms to handle simple matters like this.
Whatever you do, do NOT go to an "immigration consultant" in the US, because it is doubtful that they will be sufficiently knowledgable and experienced with Canadian law; and be very wary of immigration consultants in Canada. There are a very few reputable firms, and a lot of very shady and incompetent consultants, because that industry has just never been properly regulated here.