Protein found in brain cells may be key to autism (BBC)

Scientists have shown how a single protein may trigger autistic spectrum disorders by stopping effective communication between brain cells.

The team from Duke University in North Carolina created autistic mice by mutating the gene which controls production of the protein, Shank3.

The animals exhibited social problems, and repetitive behaviour - both classic signs of autism and related conditions.

The Nature study raises hopes of the first effective drug treatments.
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While hundreds of genes linked to the condition have been found, the precise combination of genetics, biochemistry and other environmental factors which produce autism is still unclear.
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more: http://www.bbc.co.uk/news/health-12759587

Of course it's partially genetic and I guess I'm happy they're even looking, but goodness, how long can you miss the elephant stinking up the room? Take genetics, add environment and shake. Presto, voila. And in case you think I'm being callous, my 15 year old is severely autistic.