Sugar rush

http://www.economist.com/blogs/dailychart/2011/06/diabetes

The progress of a disease over thirty years

THE number of adults with diabetes more than doubled between 1980 and 2008, according to a new study led by Professor Majid Ezzati of Imperial College London and Goodarz Danaei at Harvard University and published in the Lancet. This jump is not quite as horrific as the numbers might initially suggest, because ageing helped push up rates. But a good 30% of the increase was caused by higher prevalence of diabetes across age groups. Obesity seems to be a main culprit; the authors found a high correlation between rising rates of diabetes and a rise in body mass index. The global leap masks considerable variation between the sexes and among regions. Across the world the rate of diabetes rose by 18% for men and by 23% for women, to 9.8% and 9.2% respectively. In some countries the gap between the sexes was more dramatic. In Pakistan, for example, rates jumped by 46% for men and by 102% for women. The highest incidence of all is found in the Marshall Islands, where more than a quarter of all adults had diabetes in 2008. America has lived up to its hefty reputation. Women’s rate of diabetes jumped 79%, something that has contributed to a decline in life expectancy among some groups. And once again, French women are the envy of the world. Rates there fell by 11.2%.

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The liver turns excessive carbs into fat.

http://www.diabetes.org/diabetes-basics/diabetes-myths/

Myth: If you are overweight or obese, you will eventually develop type 2 diabetes.

Fact: Being overweight is a risk factor for developing this disease, but other risk factors such as family history, ethnicity and age also play a role. Unfortunately, too many people disregard the other risk factors for diabetes and think that weight is the only risk factor for type 2 diabetes. Most overweight people never develop type 2 diabetes, and many people with type 2 diabetes are at a normal weight or only moderately overweight.


Myth: Eating too much sugar causes diabetes.

Fact: No, it does not. Type 1 diabetes is caused by genetics and unknown factors that trigger the onset of the disease; type 2 diabetes is caused by genetics and lifestyle factors. Being overweight does increase your risk for developing type 2 diabetes, and a diet high in calories, whether from sugar or from fat, can contribute to weight gain. If you have a history of diabetes in your family, eating a healthy meal plan and regular exercise are recommended to manage your weight.

Excess sugars (fructose, lactose, glucose) in the blood stream IS diabetes. And it is much more prevalent in people who are 30% overweight or more.

What constitutes "too much sugar" varies between people and over time. Once your pancreas is max'd out (or cancerous) you are diabetic.

those 'myths' were clipped from their website.

The evidence is that dietary items per se are not linked to diabetes.

As the clips say, being overweight is a contributing factor to type II diabetes. The confounding evidence suggesting overweight does not cause diabetes by itself is that a majority of overweight people don't get diabetes.

I think it's a rather over-narrow view to think that pancreatic insulin insufficiency is the whole story on type II diabetes. It is probably the case that hyperglycemia can be the outcome of any of multiple metabolic pathways.

Examples of evidence for more than pancreatic failure is suggested by the activity of a non-insulin diabetes drug. Metformin (Glucophage)--a long standing oral medication for type II diabetes--acts on sites OUTSIDE the pancreas. Metform's effects both lower sugar production in the liver, and increases uptake of sugar and apparently glyconeogenesis in skeletal muscle.

And have continued to keep them within normal range.

So the American Diabetes Assn can keep on saying it's just more calories and not what kind of calories. It's the sugar calories. For me it is, anyway.

the huge increase in diabetes.

http://www.france24.com/en/20110621-high-dose-anti-cholesterol-drugs-linked-diabetes

http://www.reuters.com/article/2010/09/29/us-antidepressant-diabetes-idUSTRE68S57X20100929