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weakens the immune system; etc.
is documented to be a factor in several chronic children's conditions
Fluoroquinolone antibiotics have been found to cause peripheral neuropathy(13). This study found that many cases are severe and long term, with some cases affecting many organs. Of the cases followed in this study, 70% lasted more than 3 months and 58% more than one year. Examples of fluoroquinolones causing PN are levofloxacin, ciprofloacin,afloxa
Most cases of acute generalized exanthematic pustulosis(AGEP) are drug induced, and get better after cesation of drug use. amoxicillin, pristinamycin, hydroxychloroquine, ampicillin, diltiazem, co-trimoxazole, terbinafine, carbamazepine and spiramycin have most cases. (14)
Studies have found pharmaceutical use to be a leading cause of hospitalizations and the third leading cause of deaths(1). In 1998 an extensive study published in the Journal of the American Medical Association (JAMA) showed that 106,000 people die each year in American hospitals from medication side effects (1). But studies also show that less than 5% of hospitalizations and deaths due to pharmaceuticals are identified as such so the actual total is much higher.
13. J.S. Cohen, Peripheral Neuropathy Associated with Fluoroquinolones, The Annuls of Pharmacology, 2001, Vol 35, Dec. 14. Saissi EH, Drugs associated with acute generalized exanthematic pustulosis. Ann Dermatol Venereol. 2003 Jun-Jul; 130(6-7): 612-8.
1. Journal of the American Medical Association(JAMA) 2000;284:483-485; &. Lazarou J; Pomeranz BH; Corey PN. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA, 1998 Apr 15, 279(15):1200-5; & Angell, "Is Academic Medicine for Sale?", p.128; & www.healingdaily.com/conditions/pharmaceutical companies.htm; &(b) J. Lyle Bootman, PhD,Dean and Professor, College of Pharmacy, The University of Arizona,1703 E. Mabel, Tucson, Arizona 85721; & Johnson/Bootman Arch Intern. Med Vol 155 Oct 9, 1995; www.who.int/dap icium/posters/4f1_Text.html; & Bootman@elixir.pharm.arizona.edu; & (c) Weinberger M, Murrary MD, Marrero DG, Brewer N, Lykens M, Harris LE et al. Effectiveness of pharmacist care for patients with reactive airways disease: A randomized controlled trial. JAMA 2002;288(13):1594-1602. www.uic.edu/pharmacy/services/di/jamapharm.htm
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