Common drugs hasten decline in elderly: study

CHICAGO (Reuters) - Elderly people who took commonly prescribed drugs for incontinence, allergy or high blood pressure walked more slowly and were less able to take care of themselves than others not taking the drugs, U.S. researchers said on Saturday.

They said people who took drugs that block acetylcholine -- a chemical messenger in the nervous system critical for memory -- functioned less well than their peers.

"These results were true even in older adults who have normal memory and thinking abilities," said Dr. Kaycee Sink of Wake Forest University School of Medicine in North Carolina, who led the study of 3,000 people of whom 40 percent were taking more than one anticholinergic drug.

"The effect is essentially that of a three- to four-year increase in age. So someone who is 75 in our study and taking at least one moderately anticholinergic medication is at a similar functional level to a 78 to 79-year-old," Sink said in an e-mail.

Sink's findings, presented at American Geriatrics Society Meeting in Washington, add to a growing body of research that suggests these so-called anticholinergic medications can hasten functional and cognitive declines in elderly people.

Yahoo