Painkiller may cut dementia risk (BBC) {Ibuprofen vs Alzheimer's}

Long-term use of ibuprofen may reduce the risk of developing Alzheimer's disease, a large US study reports.

Data from almost 250,000 veterans showed those who used the painkiller for more than five years were more than 40% less likely to develop Alzheimer's.

The study in Neurology reported that some other similar painkillers may also have a protective effect.

Dementia experts said the results were interesting but warned against people taking ibuprofen to reduce their risk.

It is not the first time an association between non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, and Alzheimer's disease has been reported but results have been conflicting.
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more: http://news.bbc.co.uk/1/hi/health/7380064.stm

...it's my go-to drug of choice

Ibuprofen seems to also dramatically cut the risk of various cancers - breast, lung, and colon are the ones that (I think) I recall.

It is very hard on the kidneys. If you have impaired kidney function, stay away from it, as well as Aleve.