Why just one cigarette can hook some smokers

Warpy

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Wed Aug-06-08 05:32 PM
Original message

Why just one cigarette can hook some smokers

CHICAGO - For some people, one cigarette is all it takes to become hooked on nicotine, while others are repelled by it.

Researchers in Canada have found a region in the brains of rats that may be the key to these differences.

By manipulating specific molecular doorways into brain cells called receptors, they were able to control which rats in the study enjoyed their first exposure to nicotine and which were repelled by it.

Much more at http://www.msnbc.msn.com/id/26043695/

This also has the potential for explaining rapid addiction to other substances.

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hedgehog

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Wed Aug-06-08 05:33 PM
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1. It was long ago, a simpler time......

http://www.milkandcookies.com/link/87266/detail/

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Xipe Totec

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Wed Aug-06-08 05:36 PM
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2. Not me

It took hundreds of cartons of cigarrettes to get me hooked.

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Celebration

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Wed Aug-06-08 05:56 PM
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3. "there, but for the grace of God, go I"

Luck of the draw, I guess. I have smoked about 200 cigarettes in my life-- 175 of them were probably decades ago.

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Warpy

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Wed Aug-06-08 08:06 PM
Response to Reply #3

9. I tried every drug I could get my hands on in the 60s

including coke and heroin. Acid was impressive. Coke and heroin were both big yawns to me.

Yet I saw people who did either drug fall in love with it the first time they tried it and not want to do anything else for the rest of their lives but stay high.

I've always thought it was brain chemistry since there was absolutely no way to predict beforehand who it would happen to.

Every bit of research they do on nicotine tachyphylaxis and addiction is a step closer to understanding the whole addiction puzzle for all other substances and perhaps for some behaviors.

It's certainly not morality and it's not personality. It has to be something else.

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elehhhhna

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Wed Aug-06-08 06:02 PM
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4. True. Here's the one that got me started:

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Celebration

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Wed Aug-06-08 06:06 PM
Response to Reply #4

5. pretty sure my mom smoked because of the movies--POST WAR

She quit because of me and my inherent aversion. It probably extended her life a couple of years.

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Jane Austin

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Wed Aug-06-08 06:20 PM
Response to Reply #4

7. Did you ever see Hatari?

It starred some slinky gal with great hair who never stopped smoking.

That's the movie the Baby Elephant Walk came from.

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elehhhhna

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Thu Aug-07-08 08:34 AM
Response to Reply #7

12. Yes!

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Jane Austin

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Wed Aug-06-08 06:18 PM
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6. That happened to me when I was 18

and a counselor at camp.

I couldn't get enough of them.

It took me 23 years to kick 'em for good.

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applegrove

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Wed Aug-06-08 07:10 PM
Response to Reply #6

8. I just quit after 27 years. I had a great aunt who smoked and my friend's

parents both smoked. So my brain was primed to be subseptable to cigarettes. I loved them from the first time I tried them.

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Jane Austin

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Wed Aug-06-08 09:17 PM
Response to Reply #8

10. Good for you for quiting!

The best part about quitting? You'll never have to worry about quitting again. :)

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applegrove

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Thu Aug-07-08 08:07 AM
Response to Reply #10

11. I used Champix so my quit was relatively pain free. Still I am proud.

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