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Henrietta Lacks’ ‘Immortal’ Cells

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Blue_Tires Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-02-10 12:42 AM
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Henrietta Lacks’ ‘Immortal’ Cells
Medical researchers use laboratory-grown human cells to learn the intricacies of how cells work and test theories about the causes and treatment of diseases. The cell lines they need are “immortal”—they can grow indefinitely, be frozen for decades, divided into different batches and shared among scientists. In 1951, a scientist at Johns Hopkins Hospital in Baltimore, Maryland, created the first immortal human cell line with a tissue sample taken from a young black woman with cervical cancer. Those cells, called HeLa cells, quickly became invaluable to medical research—though their donor remained a mystery for decades. In her new book, The Immortal Life of Henrietta Lacks, journalist Rebecca Skloot tracks down the story of the source of the amazing HeLa cells, Henrietta Lacks, and documents the cell line's impact on both modern medicine and the Lacks family.

Who was Henrietta Lacks?
She was a black tobacco farmer from southern Virginia who got cervical cancer when she was 30. A doctor at Johns Hopkins took a piece of her tumor without telling her and sent it down the hall to scientists there who had been trying to grow tissues in culture for decades without success. No one knows why, but her cells never died.

Why are her cells so important?
Henrietta’s cells were the first immortal human cells ever grown in culture. They were essential to developing the polio vaccine. They went up in the first space missions to see what would happen to cells in zero gravity. Many scientific landmarks since then have used her cells, including cloning, gene mapping and in vitro fertilization.

There has been a lot of confusion over the years about the source of HeLa cells. Why?
When the cells were taken, they were given the code name HeLa, for the first two letters in Henrietta and Lacks. Today, anonymizing samples is a very important part of doing research on cells. But that wasn’t something doctors worried about much in the 1950s, so they weren’t terribly careful about her identity. When some members of the press got close to finding Henrietta’s family, the researcher who’d grown the cells made up a pseudonym—Helen Lane—to throw the media off track. Other pseudonyms, like Helen Larsen, eventually showed up, too. Her real name didn’t really leak out into the world until the 1970s.

How did you first get interested in this story?
I first learned about Henrietta in 1988. I was 16 and a student in a community college biology class. Everybody learns about these cells in basic biology, but what was unique about my situation was that my teacher actually knew Henrietta’s real name and that she was black. But that’s all he knew. The moment I heard about her, I became obsessed: Did she have any kids? What do they think about part of their mother being alive all these years after she died? Years later, when I started being interested in writing, one of the first stories I imagined myself writing was hers. But it wasn’t until I went to grad school that I thought about trying to track down her family.

Read more: http://www.smithsonianmag.com/science-nature/Henrietta-Lacks-Immortal-Cells.html#ixzz0eM2NwIur
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quiet.american Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-02-10 04:08 PM
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1. What an absolutely amazing story. The profiteering makes me mad as hell, though.
I saw red when I read this:

"Deborah’s brothers, though, didn’t think much about the cells until they found out there was money involved. HeLa cells were the first human biological materials ever bought and sold, which helped launch a multi-billion-dollar industry. When Deborah’s brothers found out that people were selling vials of their mother’s cells, and that the family didn’t get any of the resulting money, they got very angry. Henrietta’s family has lived in poverty most of their lives, and many of them can’t afford health insurance. One of her sons was homeless and living on the streets of Baltimore. So the family launched a campaign to get some of what they felt they were owed financially. It consumed their lives in that way.

A *multi-billion dollar industry" was launched from this, and the family has lived in poverty all these years. All this time, Henrietta's family has been in a financial wilderness while others became rich off her cells that were taken for use without her permission. Ugh! :grr:







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Fire1 Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Feb-04-10 01:18 PM
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3. "Deborah's brothers, though, didn't think much about the cells
until they found out there was money involved." HA! Nevermind, that they were taken advantage of by a multi-billion dollar industry but in the same instance degrade the brothers, implying that they didn't care about anything but the money.

Kinda hard to take the moral high ground after you've scammed a family for decades. Will wonders never cease. Sad.

Glad you posted that segment. I didn't read the Smithsonian article until now. Thanks.
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Fire1 Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-02-10 07:25 PM
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2. Another chapter in AA history. Thanks much. n/t
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