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OOPSIE! H1N1 flu vax will require 2 shots, 3 weeks apart?!!

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elehhhhna Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Sep-03-09 04:52 PM
Original message
OOPSIE! H1N1 flu vax will require 2 shots, 3 weeks apart?!!
Swine Flu Immunity May Be Delayed by Vaccine Choice (Update1)
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By Tom Randall

Sept. 3 (Bloomberg) -- Americans may need two vaccine doses instead of one to be immunized against swine flu because officials plan to exclude ingredients used to boost immune responses in shots made by Novartis AG and GlaxoSmithKline Plc.

Novartis AG today reported that a single dose of its vaccine, which relies on a shot-boosting ingredient known as an adjuvant, safely provoked a strong immune response in a trial of 100 healthy volunteers. The formulation favored by the U.S. doesn’t use an adjuvant, and a second vaccine dose is more likely to be required, said Thomas Frieden, director of the U.S. Centers for Disease Control and Prevention.

The U.S. paid Novartis, based in Basel, Switzerland, and London-based Glaxo more than $415 million for emergency stockpiles of adjuvant, which isn’t approved by the Food and Drug Administration. Vaccines are slated to arrive in mid- October, a time that health officials say could be the peak of outbreaks. A second dose would need to be given three weeks after the first, delaying immunity.

“We expect that the likelihood of needing two doses of vaccine that’s not adjuvanted is higher than with an adjuvanted vaccine,” Frieden said today in a conference call. “We don’t anticipate that we’ll be using adjuvanted vaccine in most of the scenarios that we anticipate now, though that could change.”

http://www.bloomberg.com/apps/news?pid=20601124&sid=aiU_.gJY53E8
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Chemisse Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Sep-03-09 05:04 PM
Response to Original message
1. Better to have to get it twice than to have questionable adjuvant
Nevertheless, I don't expect a stellar turnout for this.

My workplace is preparing to give the regular flu vaccine. Well, I never get a flu shot anyway, but I sure wouldn't get one after reading that the swine flu dominates the others.
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kumbaya Donating Member (53 posts) Send PM | Profile | Ignore Sat Sep-05-09 09:45 PM
Response to Reply #1
11. I am with you...They pushed the panic on us last spring
and it's baaack! And so many are on auto pilot. They just don't think for themselves.

There are so many variations of the flu that it is ludricrous to think one is protected by a particular shot. What is worse, it seems like the viruses are mutating and turning into super strains. I get colds and rarely flus, but in the last year, I have had two bouts of the flu and a nasty-ass respiratory thing which I NEVER got when I stopped taking stuff for colds and the flu!:mad:
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Warpy Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Sep-03-09 05:08 PM
Response to Original message
2. Don't panic yet. Articles out today said one shot is possible
Novartis: One-dose H1N1 flu vaccine a possibility

BARCELONA, Spain – A third company signaled today that its H1N1 flu vaccine may protect people with just one shot instead of two – another hopeful sign for flu prevention efforts.

Swiss drugmaker Novartis joins two Chinese companies that say the vaccine can be produced in one dose.

In early results from human tests on one of its H1N1 flu vaccine candidates, Novartis AG said one shot of its vaccine provided enough protection against the virus, as set out by criteria by U.S. and European drug regulators.

“The pilot results are encouraging,” Andrin Oswald, CEO of Novartis Vaccines and Diagnostics, said in a statement. “This is important information for public health authorities who prepare for vaccination in the coming months with limited vaccine supply.”

More at http://www.argusleader.com/article/20090903/UPDATES/90903024
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elehhhhna Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Sep-04-09 02:42 PM
Response to Reply #2
5. Oh great! The Chinese say only one dose...is that with melamine or without?
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Warpy Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Sep-05-09 11:31 AM
Response to Reply #5
7. If you'd read the article, or even the whole post,
Edited on Sat Sep-05-09 11:31 AM by Warpy
you'd realize that this particular company is in Switzerland, not China.
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kimmerspixelated Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Sep-03-09 05:31 PM
Response to Original message
3. No thanks, I pass.
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undeterred Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Sep-03-09 05:33 PM
Response to Original message
4. Who is paying for uninsured people to be vaccinated?
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elehhhhna Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Sep-04-09 02:59 PM
Response to Reply #4
6. hardee-har-har! NOBODY!
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Fire_Medic_Dave Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Sep-05-09 11:32 AM
Response to Reply #4
9. Local health departments.
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yost69 Donating Member (131 posts) Send PM | Profile | Ignore Sat Sep-05-09 11:28 PM
Response to Reply #4
14. You are. Isn't that great?
Just like the health plan proposed you are paying for the uninsured with your tax dollars.
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Fire_Medic_Dave Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Sep-05-09 11:32 AM
Response to Original message
8. That's what been slated to be used in the US the entire time. Where is the oopsie?
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BlooInBloo Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Sep-05-09 11:34 AM
Response to Original message
10. Requires *no* shots for me.
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WeDidIt Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Sep-05-09 09:46 PM
Response to Original message
12. That's because unlike standard flu strains
Edited on Sat Sep-05-09 09:47 PM by WeDidIt
there is no pre-existing immunity levels within humans for H1N1.

You require a single standard flu shot beause you already have some immunity.

Thi9s is standard immunology, not some conspiracy or profit motive.
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crazylikafox Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Sep-05-09 09:48 PM
Response to Original message
13. Two shots. Guess that means we have to pay twice. Extra money for Novartis.
Who woulda thunk it?
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kentuck Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Sep-05-09 11:37 PM
Response to Original message
15. Does anyone know?
If you are working in a place with about 100 people and only one person has decided to take the flu shot, can he pass that flu on to the other 99 people, since the flu shot is just a small dose of the same flu, we are told?
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