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Swine Flu Question: Will this vaccine protect you if the flu mutates?

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Junkdrawer Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Oct-17-09 04:02 PM
Original message
Swine Flu Question: Will this vaccine protect you if the flu mutates?
And I'm guessing this is not a yes or no question, but a "how much" question.
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Ezlivin Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Oct-17-09 04:07 PM
Response to Original message
1. What if I mutate?
Will you be safe?

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TwilightGardener Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Oct-17-09 04:15 PM
Response to Reply #1
7. *snicker*
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Contrary1 Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Oct-17-09 04:09 PM
Response to Original message
2. Good question. I found this info:
"At this stage, it is impossible to predict if or how the H1N1 swine flu virus will mutate (change). However, experiences with the H5N1 bird flu vaccine would suggest that an H1N1 vaccine would also provide a high level of immunity against closely related strains. The level of cross-protection is expected to be greatest for more closely related strains."

http://www.nhs.uk/conditions/pandemic-flu/pages/qa.aspx#stillprovideprotection


"Typically each year, one or two of the viruses in the flu shot are updated to anticipate mutations. However, if a major “shift” occurs, or the virus mutates to a different form than what researchers anticipated, the shot may not cover some of the circulating viruses. If there are viruses circulating that are not covered by the flu shot, you may still get the flu even if you had a flu shot.
The good news is that the antibodies your body produces to fight the viruses in the flu shot are typically able to provide some resistance to mutated versions of that virus. Even if it does not prevent the illness, you are more likely to have a less severe case of the illness if you have had a flu shot."

http://coldflu.about.com/od/fluvaccinequestions/a/07-08flushot.htm
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Ruby the Liberal Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Oct-17-09 04:23 PM
Response to Reply #2
10. Thanks for the link. I am still trying to decide also.
Leaning toward no, but still trying to learn.
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dbonds Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Oct-17-09 04:11 PM
Response to Original message
3. It depends on the mutation.
If it mutates where the antibodies can't recognize it signature and destroy it then the vaccine won't help. But I think the odds of that are very very low.
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old mark Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Oct-17-09 04:11 PM
Response to Original message
4. No. It won't protect you from being hit by a bus, either.....nt
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cynatnite Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Oct-17-09 04:12 PM
Response to Original message
5. You do know there are two different kinds of vaccines, don't you?
One with thimerosal and one without. My daughter is pregnant and getting the one without.
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betharina Donating Member (313 posts) Send PM | Profile | Ignore Sat Oct-17-09 04:25 PM
Response to Reply #5
11. can i ask from where? i am trying to locate the mercury free vaccine. nt
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cynatnite Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Oct-17-09 04:37 PM
Response to Reply #11
13. Well, the doctors here will only give them to select patients...
such as my pregnant daughter. I've been told that supplies are very limited. I'm guessing you'll have to ask your doctor about it. We're in NE TN.
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betharina Donating Member (313 posts) Send PM | Profile | Ignore Sun Oct-18-09 08:44 PM
Response to Reply #13
19. thanks. nt
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Name removed Donating Member (0 posts) Send PM | Profile | Ignore Sat Oct-17-09 04:13 PM
Response to Original message
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derby378 Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Oct-17-09 04:17 PM
Response to Original message
8. I already have swine flu, so I'm developing antibodies as I type this
As for mutations, the most difficult thing about being an epidemiologist is that you have to prove yourself to be smarter than the pathogen you're trying to contain. Back in the late 80s and early 90s, the AIDS virus mutated so often it had researchers pulling out their hair.
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Junkdrawer Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Oct-17-09 04:30 PM
Response to Reply #8
12. I found this Googling around:
Swine flu could protect against deadly mutation: experts

That is what happened in 1918, when most people who fell ill with a mild Spring flu were effectively inoculated from the far more lethal strains that roared back a few months later and killed at least 40 million worldwide, according to recent and upcoming studies.

The death rate among those infected during the first wave was 70 percent lower, according to groundbreaking research published in November in the Journal of Infectious Diseases.

The findings suggest that going all-out to prevent exposure to the kind of non-seasonal flu sweeping across the world today may turn out to be counter-productive in the fight to reduce mortality.

Health officials around the world have taken decisive measures to halt the flu's spread, including closing schools and quarantining travellers.

Mexico City, the epidemic's epicentre, was essentially shuttered for five days until Wednesday.

"In 1918, with the benefit of 20/20 hindsight, it would have been better to allow a first wave of infection in order to build immunity to the merging virus while it was still mild," said Lone Simonsen, an epidemiologist at George Washington University and a co-author of the November study.

...


http://www.physorg.com/news160896138.html
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derby378 Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Oct-17-09 04:50 PM
Response to Reply #12
16. Yay! *cough*
It'll be interesting to see if this is really a blessing in disguise.
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tblue Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Oct-17-09 04:18 PM
Response to Original message
9. The tests to determine if you even have H1N1 are largely inaccurate, so WTH knows?
I'm gonna get the vaccination if it becomes available where I live. I already wash my hands a lot and do what I usually do to try to stay healthy. Otherwise, I'm not gonna think about it. I've really got Terror Fatigue. Do they have a shot for that?
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stray cat Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Oct-17-09 04:47 PM
Response to Reply #9
15. The rapid swab test is inaccurate; however, the PCR tests are very good
as is DNA sequencing. (those are the tests people use if they are actually confirming infection or studying the virus)
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tblue Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Oct-17-09 10:02 PM
Response to Reply #15
17. Okay. Thanks. I talked to a friend just today whose son may have it, and she
said the doctor did not advise testing, citing its inaccuracy, and saying the treatment would be the same either way. I'm sure you are right. There's some reason they don't do the other test. It's expensive, I think I heard.

Poor kid looks like he has pneumonia now. He already has some other disability. Not sure what exactly cuz I've never inquired what it is (hard to ask). I feel so bad for him. He's been sick for almost a week now.
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uppityperson Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Oct-17-09 10:05 PM
Response to Reply #15
18. I've done rapid test on 2 people, both were neg, still sure 1 had it though
classic symptoms but neg on rapid test. We didn't do the longer test since treating presumptively on symptoms, but it made me more leery of trusting the test. Nice there is a rapid test, but still.
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stray cat Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Oct-17-09 04:45 PM
Response to Original message
14. Good news - first H1N1 surprisingly is not mutating so the vaccine match remains excellent
even if it did at least this year the vaccine is sufficiently targeted that it would still be signficantly protective.
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Fire_Medic_Dave Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Oct-18-09 09:28 PM
Response to Reply #14
20. Now that it is being widely challenged by anti-virals it will mutate much faster.
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girl gone mad Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Oct-18-09 09:36 PM
Response to Original message
21. Maybe, but..
there is also a good chance that it won't. To get the vaccine out in time, only 1 virus profile was used. Typical flu vaccines use at least 2, more recently 3 to improve the chances of a match.
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