with Gupta - sanity prevails. Ganja will soon be legal and ganja for medical use has gained significant ground.

Your OP needs to be seen - get thee to the greatest page.

gave me faith in the FDA.

She presented her findings - that you would need to sit in a bathtub full of hemp oil for three days for it to even register in a blood test were not met with happy faces from the GWB team that wanted to be able to ban it.

She then said, "You know that poppy seed bagel you're eating? That will show up in your bloodwork today. You'd need to ban those before cosmetic hemp oil."

They told her to edit her research to make it more acceptable to them, and she refused. She said, "Here's my research. YOU edit it. I'm a scientist, not a lawyer."

"Here's my research. YOU edit it. I'm a scientist, not a lawyer."

Perfect. We need more folks like her.

seizures. I'm very glad they are doing this.

And the finding that doesn't have abuse potential even at high doses is very important, and will squelch much of the political ammuntion against it.

last year. I hope they approve it Federally.

Many states are selling it. I take a smaller measure to help with sleep.

Mahalo, ehrnst

While it's great news the FDA is recognizing thew medical benefits of CBD, this is NOT good news.

CBD is simply a plant extract from hemp and cannabis plants. It's very easy to isolate, even in a near pure form, but it is MOST effective when combined with THC. So it's pure form isn't necessarily the best form overall, but it may be for very young children, that's not the issue.

The issue is that once a drug is controlled by the FDA, they quickly move to regulate it's availability and distribution. This will likely lead to having only a few sources available, under pharma giant control.

So an easy to extract plant compound, completely safe even when combined with thc and other plant terpines, becomes highly regulated and priced accordingly. Any doctor who wants to prescribe cbd for these conditions, will have to prescribe this one approved drug source.

While purity and standards to manufacture are great things to have, are they necessary in this case?

Again, it's great the fda is recognizing the benefits of cannabis compounds, but this is where the battle for medical availability will be. Big Pharma will control the market and pricing. Not a good thing.

so access won't be a problem

Last edited Fri Apr 20, 2018, 09:47 AM - Edit history (1)

In the case of Mifepristone (which is the first part of the regimen in RU486) my friend was also on the panel testing it.

They made strict recommendations as to how it could be used (orally only, not vaginally - which was also a common and effective way to adminster it especially with patients with nausea), and the first dose had to be given by a health provider in an office setting.

While that appears to be restricting the drug and making it less available, it actually was protective of a drug that they knew would be challenged the minute someone had a reaction to it.

If someone who was taking it "off label" had a reaction, the drug itself could be defended against the throngs of anti-choicers, because of the off-use label of it. If the first dose is required to be taken in a doctor's office, there is no way that the claims of anti-choicers that "it could be slipped into a woman's drink without her knowing it" are accurate.

In a scientific setting, they need certain metrics on controls, and the purity of the oil is one of them. Otherwise the data isn't good.

Also, dosage is absolutely important, and impurity - not matter if it's harmful or not - affects dosage.

The job of this panel is to do scientific research, using good scientific methods, so there is no question about the efficacy of a particular substance. They did their job.

End of story.

Snake oil salesmen will always try to make a buck off people who are suffering, and need to be held accountable by a professional body that answers only to the public.


https://en.wikipedia.org/wiki/Pure_Food_and_Drug_Act

and supplements being capsules filled with sand. Until someone investigates for fraud, there is no oversight:

https://www.cbsnews.com/news/herbal-supplements-targeted-by-new-york-attorney-general/

But they are out of the FDA jusrisdiction, unless they make claims that a supplement will treat or cure a condition.

Hence the "This product is not intended to diagnose, treat, cure, or prevent any disease;" or. plural: "These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease" disclaimer, so they can avoid the FDA inspection and verification requirements for drugs. They are considered food, not drugs.

then it's an improvement. Certainly there are problems in the pharmaceutical industry, and yes "they" will control the supply of an approved drug by definition. But it's unlikely to be controlled by a single company since CBD cannot be patented.

Which implies that at the very least medical use around children can be considered as benign as drinking a glass of wine or taking one's regular medicine around children at dinner - it's not "child endangerment" to have it at home with kids around if stored and used appropriately.

I only agree with you somewhat on Big Pharma.
Luckily, research and studies on unadulterated CBD safety and effectiveness will not be as complex as the research and studies on synthetics and complex biologics - and universities will probably be ready to start much of the groundwork research on the taxpayer dime. From research I was doing for my spouse when he was contemplating medical MJ, there's already been final studies on effective dosages and deployment of CBD for pain done in Europe and with the NIH - two years ago.
I used those studies to figure out how much CBD oil (from a reliable source) I needed to use to make and "dose" his edibles to be effective on a daily and not impact his cognitive and reactive awareness. (He had to go with edibles because I work in a field where drug-testing is always a possibility.)

CBD studies will probably be closer in complexity to studies on salicylic acid. Compounding pharmacies will be able to replicate much of the components at a reasonable cost - especially since politicians like Weld and Boehner are already getting involved in Cannabis products.

So I don't think CBD-based products would end up being outrageously expensive, either from a manufacturer or from a compounding source. It's the specialty synthetics and genetically designed drugs that burden the patient.

Haele

It isn't helping me.

There was a review of studies done a few years ago that concluded that it was effective in some cases.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2503660/

Spouse has fibromyalgia and arthritis. CBD oil works for him in a cream form with a few other components that a trusted source created for her mother who has the same issues. He also takes methotrexate and Humira (a bi-weekly injection that costs $2800 a shot if you don't have insurance and a discount plan...) to keep the physical deterioration at bay, so there's several things going on there.
But CBD oil has never worked for his muscle pain, nor for sprains or other strain or tension type pain. A prescription cream called Voltarin and a TENS machine works better for those.

Haele

My neurologist would prescribe any cannabis product, if it were legal in my state. She's a believer! However, instead of cannabis, she's "forced" to administer Botox treatments....30 shots of poison around the hairline and other points, every 3 months, no proven success rate and $3,000. a pop! No thanks....

I would not want to try to verify the purity, or ingredients in regular, unlicensed mail order CBD sources, but the Canadian government inspects any drug that comes into Canada that is intended for dispensing to Canadians, and licenses sources.

trying to take CBD oil across the border!

prescription or not. I was told if one wanted to vacation in Colorado to check out the dispensaries you should NOT say anything at customs or you could be refused entry!

I'll send her an email asking....

Thank you, ehrnst!

It was horrible I must have outgrown them as I rarely get a headache anymore. Both parents suffered with them. To get to my point my niece also has them, she said she called some cbd oil and instantly her headache was gone. Can you order it online?

Migraines are very hereditary but unpredictable. Unfortunately, mine were passed down from both sides. My son started getting them at age 8, my daughter has never had one. My 8 year grandson has had 2 episodes.

So glad yours have gone away! And that your niece has found some relief! I will look online and also in the "head" shops in my college city.

Thanks so much!

That was new info for me; I'm just happy this is helping. (I don't think pot is legal for her in her state.)

Our next door neighbor smokes pot for his migraines, and has for years, long before it was legal here in California -- I'm sorry this is not accessible for you to at least try.

I've been on them, also meds for epilepsy, Alzheimer's, seizures, anxiety, etc. We've tried everything.... currently my neuro has me on just supplements. At least they aren't poison. Barometric pressure is my biggest trigger and I have no control over that.

I take advantage of local sources for the natural relief, if you catch my drift....

The migraines are something I just live with and tell myself it could be so much worse. Still, if this alternative was available, my life could be so much more productive.

Thanks for the info, I'm glad your sister and neighbor have found relief!