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Quixote1818

(28,950 posts)
Wed Jan 23, 2019, 11:25 PM Jan 2019

The Cause of Alzheimer's Could Be Coming From Inside Your Mouth, Study Claims

PETER DOCKRILL 24 JAN 2019
In recent years, a growing number of scientific studies have backed an alarming hypothesis: Alzheimer's disease isn't just a disease, it's an infection.

While the exact mechanisms of this infection are something researchers are still trying to isolate, a litany of papers argue the deadly spread of Alzheimer's goes way beyond what we used to think.

Now, scientists are saying they've got one of the most definitive leads yet for a bacterial culprit behind Alzheimer's, and it comes from a somewhat unexpected quarter: gum disease.

In a new paper led by senior author Jan Potempa, a microbiologist from the University of Louisville, researchers report the discovery of Porphyromonas gingivalis – the pathogen behind chronic periodontitis (aka gum disease) – in the brains of deceased Alzheimer's patients.

More: https://www.sciencealert.com/new-evidence-reveals-an-unexpected-culprit-behind-alzheimer-s-disease?fbclid=IwAR1ESD82Mur95KENttl-Nw1j8EVYWWMCYAZvU6UFG11B9lZCrRi4EkGbRwA

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The Cause of Alzheimer's Could Be Coming From Inside Your Mouth, Study Claims (Original Post) Quixote1818 Jan 2019 OP
So how do people with no teeth get Alzheimer's? dhol82 Jan 2019 #1
It's probably 2naSalit Jan 2019 #2
Each tooth has a tendon. If not taken out then it causes cpamomfromtexas Jan 2019 #7
So how does that necrosis have any bearing on Alzheimer's? dhol82 Jan 2019 #8
Necrosis is infection from the way it was explained to me cpamomfromtexas Jan 2019 #12
Yes, but which bacteria are involved? dhol82 Jan 2019 #17
Necrosis is actually tissue death. Dave Starsky Jan 2019 #22
Necrosis can lead to infection but is not itself, infection Maru Kitteh Jan 2019 #38
Biological dentistry MattBaggins Jan 2019 #21
Evidently not. dhol82 Jan 2019 #32
Teeth have no tendons. Tendons connect muscle to bone. LakeSuperiorView Jan 2019 #28
Maybe confused with ligament Tree-Hugger Jan 2019 #33
I think you are correct. I got them mixed up. cpamomfromtexas Jan 2019 #36
Yes. Removing teeth removes the infection. dhol82 Jan 2019 #11
My mom itcfish Jan 2019 #30
As the poster child for periodontal disease all I can say is dflprincess Jan 2019 #3
That hereditary gum disease might be from contact insemination. dhol82 Jan 2019 #9
Interesting... BigmanPigman Jan 2019 #4
Does your mom use a toothpaste with malaise Jan 2019 #24
I don't know which toothpaste she uses BigmanPigman Jan 2019 #34
My mother had perio disease from age 19. marybourg Jan 2019 #29
Some day, researchers will conclude that Alzheimer's is one symptom with many causes question everything Jan 2019 #5
My money is on inflammation as the root cause of many, if not most, diseases dhol82 Jan 2019 #10
That's actually been demonstrated, to a certain extent. Dave Starsky Jan 2019 #23
Bingo. PoindexterOglethorpe Jan 2019 #13
You mean... you don't believe in... SUPERFOODS!? Dave Starsky Jan 2019 #25
+1 Auggie Jan 2019 #26
Or.... people with Alzheimer's have gum disease due to worsening brushing habits? NightWatcher Jan 2019 #6
This! Phoenix61 Jan 2019 #15
If you read further, it says that that possibility was explored, but seems less likely pnwmom Jan 2019 #20
wouldn't this be pretty apparent by looking at a map.... IcyPeas Jan 2019 #14
Thanks. I just sent this to our Supervisor who is championing help and research into Alzheimer's. Liberty Belle Jan 2019 #16
You bring up a good point, area51 Jan 2019 #18
Most people lose dental coverage when they retire SoCalDem Jan 2019 #19
Dental care is more important than is realized. And it's one thing NOT covered by Medicare. Liberal In Texas Jan 2019 #27
Touche McCamy Taylor Jan 2019 #31
Dental care in this country Tree-Hugger Jan 2019 #35
Did the numbers and decided dental insurance I had to pay for wasn't worth it. Liberal In Texas Jan 2019 #37
Dental care from a general health care perspective... Dave Starsky Jan 2019 #39

2naSalit

(86,664 posts)
2. It's probably
Wed Jan 23, 2019, 11:32 PM
Jan 2019

what caused them to lose their teeth in the first place. I wonder if removing your teeth actually ends the infection.

cpamomfromtexas

(1,247 posts)
7. Each tooth has a tendon. If not taken out then it causes
Wed Jan 23, 2019, 11:44 PM
Jan 2019

Necrosis. Just had to fix a lot of my husband’s issues. Biologic dentists have a whole other way of practicing dentistry. Much more cautious than traditional dentists.


Maru Kitteh

(28,341 posts)
38. Necrosis can lead to infection but is not itself, infection
Fri Jan 25, 2019, 03:23 AM
Jan 2019

It is simply the death of tissue. Dead tissue can facilitate an infection by providing pathogens with a nourishing medium (food).

 

LakeSuperiorView

(1,533 posts)
28. Teeth have no tendons. Tendons connect muscle to bone.
Thu Jan 24, 2019, 10:01 AM
Jan 2019

Perhaps you were thinking of nerves? Either that or you have been misinformed - either way, there are no tendons connected to teeth.

dhol82

(9,353 posts)
11. Yes. Removing teeth removes the infection.
Thu Jan 24, 2019, 12:06 AM
Jan 2019

Unless you are some whackadoodle ‘holistic’ practitioner.

itcfish

(1,828 posts)
30. My mom
Thu Jan 24, 2019, 10:47 AM
Jan 2019

had false teeth, no teeth at all, and she had Alzheimer's. I guess it depends on the type of dementia.

dflprincess

(28,080 posts)
3. As the poster child for periodontal disease all I can say is
Wed Jan 23, 2019, 11:33 PM
Jan 2019

"isn't this just ducky?"

On the other hand, periodontal disease can be herititary as can Alzheimer's. There are others in the family with gum diesease, but there has not been any Alzheimer's for at least 2 generations, though one of my great-grandmothers was said to get "childish" in her 90s.

But it is also a risk for heart diesease (I notice my annual "health risk assessment" has asked about it for a couple years now) and that runs rampant through the family.

Of course, there may also be the issue that people with dementia, in fact people in nursing homes in general, tend not to get access to good dental care. Many seniors don't, it isn't covered by Medicare.

dhol82

(9,353 posts)
9. That hereditary gum disease might be from contact insemination.
Thu Jan 24, 2019, 12:03 AM
Jan 2019

Mom has perio issues. She has rampant bacteria. She has baby food on a spoon - yum, yum, lick, lick to get baby to eat.
Voila! Bacterial insemination.
Seems as though there might be a familial predisposition to allow this.

BigmanPigman

(51,613 posts)
4. Interesting...
Wed Jan 23, 2019, 11:36 PM
Jan 2019

My mother, 84, is as sharp as a tack. Her mother died when she was 103 and didn't have any dementia until she was over 95. Both had gum disease.

BigmanPigman

(51,613 posts)
34. I don't know which toothpaste she uses
Thu Jan 24, 2019, 01:38 PM
Jan 2019

but she uses stuff (mini bottle brushes and floss thingies) to get in between her teeth throughout the day.

question everything

(47,494 posts)
5. Some day, researchers will conclude that Alzheimer's is one symptom with many causes
Wed Jan 23, 2019, 11:41 PM
Jan 2019

and pathways.

Once they, and the pharmaceutical companies that pour millions into this research, accept this, instead of ditching a study that shows only 10% improvement, will concentrate on this 10% subset.

But, no pharmaceutical companies want a "jackpot" that will treat all five million patients (in the U.S.) to generate billions of profit.

Dave Starsky

(5,914 posts)
23. That's actually been demonstrated, to a certain extent.
Thu Jan 24, 2019, 09:23 AM
Jan 2019

Inflammation releases bad chemicals that are just not good for you in the long run.

PoindexterOglethorpe

(25,865 posts)
13. Bingo.
Thu Jan 24, 2019, 12:19 AM
Jan 2019

People keep on wanting to reduce something complex to a simple cause. Alzheimer's is from gum disease is simply the most recent example.

Early onset Alzheimer's seems to be a counter example. I know a woman who was diagnosed with early onset Alzheimer's at age 50. That was about three years ago. I'm not particularly close to her or her family, but do know she's now in an Alzheimer's care unit. It's genuinely tragic. Meanwhile, her parents, now in their early 80s, are struggling to manage her. I suppose it's possible she did a crappy job of caring for her teeth and they did a good job, but somehow that seems stupidly simplistic.

I'm reminded of the crap we see all the time on the interwebs that suggest that if only you eat this one magical food, or avoid this other deadly one, you'll be protected from cancer. Bullshit.

NightWatcher

(39,343 posts)
6. Or.... people with Alzheimer's have gum disease due to worsening brushing habits?
Wed Jan 23, 2019, 11:41 PM
Jan 2019

Plus gum disease gets worse over time and effects more older than young people.

Maybe the relationship of gum disease and Alzheimer's is strictly correlation and not causation?

Phoenix61

(17,006 posts)
15. This!
Thu Jan 24, 2019, 12:37 AM
Jan 2019

The only way to prevent gum disease is regular dental cleanings which are not going to happen once Alzheimer's really hits.

pnwmom

(108,980 posts)
20. If you read further, it says that that possibility was explored, but seems less likely
Thu Jan 24, 2019, 03:33 AM
Jan 2019

because these pathogens were found in people who had not yet developed symptoms of Alzheimers. So it wasn't related to dementia patients neglecting their gums.

IcyPeas

(21,894 posts)
14. wouldn't this be pretty apparent by looking at a map....
Thu Jan 24, 2019, 12:26 AM
Jan 2019

dentistry differs from country to country (or differs between rich or poor..) So wouldn't this be more obvious when mapping out who gets it?

Are there Alzheimer clusters like there are cancer clusters?

It's interesting, but seems too simplistic to me. (but I am not a doctor).

Liberty Belle

(9,535 posts)
16. Thanks. I just sent this to our Supervisor who is championing help and research into Alzheimer's.
Thu Jan 24, 2019, 12:43 AM
Jan 2019

She just lost her husband to the disease, but led efforts before that to get funding her in San Diego to help search for a cure for Alzheimer's at our prestigious research institutions, and also get help for families caring for a loved one with the disease.

I suggested the county should start providing insurance or other help to enable people to get dental care to prevent infections that may lead to Alzheimer's and that we already know can lead to heart failure, death or heart transplant.

I think health insurance should have to cover dental care too for all non-cosmetic procedures-- especially if there is an infection or risk of one.

SoCalDem

(103,856 posts)
19. Most people lose dental coverage when they retire
Thu Jan 24, 2019, 03:26 AM
Jan 2019

and vision care.. You can pay extra , but many people who only get SS and a small pension, cannot afford it, so they do without.. Not surprising that dental issues have other consequences.. Heart disease is sometimes connected to dental issues..

Liberal In Texas

(13,559 posts)
27. Dental care is more important than is realized. And it's one thing NOT covered by Medicare.
Thu Jan 24, 2019, 09:43 AM
Jan 2019

...and should be.

Poor dental hygiene can cause:
Cardiovascular Disease.
Dementia. Poor oral health can affect the brain. ...
Respiratory Infections. ...
Diabetes. ...
Pregnancy Complications. ...
Infertility. ...
Erectile Dysfunction. ...
Cancer.

https://www.absolutedental.com/blog/10-health-issues-caused-by-bad-oral-health/

Tree-Hugger

(3,370 posts)
35. Dental care in this country
Thu Jan 24, 2019, 01:44 PM
Jan 2019

.....is very messed up. Your dental health affects your overall health, but dental insurance in America is an absolute joke.

This morning I just had one tooth worked on. It has a temp crown right now as I await a root canal in a few weeks. Between today's appointment, the root canal, and the permanent crown, I will have used up 95% of my dental insurance allotment for the year. And it doesn't even cover anything (other than basic cleaning and dad's)100%. I still have $700 out of pocket for one tooth.

I could go on and on about everything wrong with the system. Also, fuck Trump.

Liberal In Texas

(13,559 posts)
37. Did the numbers and decided dental insurance I had to pay for wasn't worth it.
Thu Jan 24, 2019, 06:50 PM
Jan 2019

And I also just had to have a root canal and a crown. Cost a fortune, but the insurance wouldn't have paid much anyway.

If one has it through employment it's bad enough.

Dave Starsky

(5,914 posts)
39. Dental care from a general health care perspective...
Thu Jan 31, 2019, 07:04 PM
Jan 2019

Is vastly underrated . It should be more focused on.

There are veins and sinuses in the head that are difficult to
treat.

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