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Related: Editorials & Other Articles, Issue Forums, Alliance Forums, Region ForumsThe Cause of Alzheimer's Could Be Coming From Inside Your Mouth, Study Claims
PETER DOCKRILL 24 JAN 2019
In recent years, a growing number of scientific studies have backed an alarming hypothesis: Alzheimer's disease isn't just a disease, it's an infection.
While the exact mechanisms of this infection are something researchers are still trying to isolate, a litany of papers argue the deadly spread of Alzheimer's goes way beyond what we used to think.
Now, scientists are saying they've got one of the most definitive leads yet for a bacterial culprit behind Alzheimer's, and it comes from a somewhat unexpected quarter: gum disease.
In a new paper led by senior author Jan Potempa, a microbiologist from the University of Louisville, researchers report the discovery of Porphyromonas gingivalis the pathogen behind chronic periodontitis (aka gum disease) in the brains of deceased Alzheimer's patients.
More: https://www.sciencealert.com/new-evidence-reveals-an-unexpected-culprit-behind-alzheimer-s-disease?fbclid=IwAR1ESD82Mur95KENttl-Nw1j8EVYWWMCYAZvU6UFG11B9lZCrRi4EkGbRwA
dhol82
(9,353 posts)2naSalit
(86,664 posts)what caused them to lose their teeth in the first place. I wonder if removing your teeth actually ends the infection.
cpamomfromtexas
(1,247 posts)Necrosis. Just had to fix a lot of my husbands issues. Biologic dentists have a whole other way of practicing dentistry. Much more cautious than traditional dentists.
dhol82
(9,353 posts)cpamomfromtexas
(1,247 posts)dhol82
(9,353 posts)Dave Starsky
(5,914 posts)It is not infection, although an infection can lead to it.
Maru Kitteh
(28,341 posts)It is simply the death of tissue. Dead tissue can facilitate an infection by providing pathogens with a nourishing medium (food).
MattBaggins
(7,904 posts)Is there no quackery too far out for DU?
dhol82
(9,353 posts)LakeSuperiorView
(1,533 posts)Perhaps you were thinking of nerves? Either that or you have been misinformed - either way, there are no tendons connected to teeth.
Tree-Hugger
(3,370 posts)Periodontal ligament. People mix up tendon and ligament.
cpamomfromtexas
(1,247 posts)dhol82
(9,353 posts)Unless you are some whackadoodle holistic practitioner.
had false teeth, no teeth at all, and she had Alzheimer's. I guess it depends on the type of dementia.
dflprincess
(28,080 posts)"isn't this just ducky?"
On the other hand, periodontal disease can be herititary as can Alzheimer's. There are others in the family with gum diesease, but there has not been any Alzheimer's for at least 2 generations, though one of my great-grandmothers was said to get "childish" in her 90s.
But it is also a risk for heart diesease (I notice my annual "health risk assessment" has asked about it for a couple years now) and that runs rampant through the family.
Of course, there may also be the issue that people with dementia, in fact people in nursing homes in general, tend not to get access to good dental care. Many seniors don't, it isn't covered by Medicare.
dhol82
(9,353 posts)Mom has perio issues. She has rampant bacteria. She has baby food on a spoon - yum, yum, lick, lick to get baby to eat.
Voila! Bacterial insemination.
Seems as though there might be a familial predisposition to allow this.
BigmanPigman
(51,613 posts)My mother, 84, is as sharp as a tack. Her mother died when she was 103 and didn't have any dementia until she was over 95. Both had gum disease.
malaise
(269,087 posts)peroxide?
BigmanPigman
(51,613 posts)but she uses stuff (mini bottle brushes and floss thingies) to get in between her teeth throughout the day.
marybourg
(12,633 posts)Lost her last tooth at 59. Sharp as a tack at 78.
question everything
(47,494 posts)and pathways.
Once they, and the pharmaceutical companies that pour millions into this research, accept this, instead of ditching a study that shows only 10% improvement, will concentrate on this 10% subset.
But, no pharmaceutical companies want a "jackpot" that will treat all five million patients (in the U.S.) to generate billions of profit.
dhol82
(9,353 posts)Dave Starsky
(5,914 posts)Inflammation releases bad chemicals that are just not good for you in the long run.
PoindexterOglethorpe
(25,865 posts)People keep on wanting to reduce something complex to a simple cause. Alzheimer's is from gum disease is simply the most recent example.
Early onset Alzheimer's seems to be a counter example. I know a woman who was diagnosed with early onset Alzheimer's at age 50. That was about three years ago. I'm not particularly close to her or her family, but do know she's now in an Alzheimer's care unit. It's genuinely tragic. Meanwhile, her parents, now in their early 80s, are struggling to manage her. I suppose it's possible she did a crappy job of caring for her teeth and they did a good job, but somehow that seems stupidly simplistic.
I'm reminded of the crap we see all the time on the interwebs that suggest that if only you eat this one magical food, or avoid this other deadly one, you'll be protected from cancer. Bullshit.
Dave Starsky
(5,914 posts)Every time I hear that term, I want to laugh out loud.
Auggie
(31,174 posts)NightWatcher
(39,343 posts)Plus gum disease gets worse over time and effects more older than young people.
Maybe the relationship of gum disease and Alzheimer's is strictly correlation and not causation?
Phoenix61
(17,006 posts)The only way to prevent gum disease is regular dental cleanings which are not going to happen once Alzheimer's really hits.
pnwmom
(108,980 posts)because these pathogens were found in people who had not yet developed symptoms of Alzheimers. So it wasn't related to dementia patients neglecting their gums.
IcyPeas
(21,894 posts)dentistry differs from country to country (or differs between rich or poor..) So wouldn't this be more obvious when mapping out who gets it?
Are there Alzheimer clusters like there are cancer clusters?
It's interesting, but seems too simplistic to me. (but I am not a doctor).
Liberty Belle
(9,535 posts)She just lost her husband to the disease, but led efforts before that to get funding her in San Diego to help search for a cure for Alzheimer's at our prestigious research institutions, and also get help for families caring for a loved one with the disease.
I suggested the county should start providing insurance or other help to enable people to get dental care to prevent infections that may lead to Alzheimer's and that we already know can lead to heart failure, death or heart transplant.
I think health insurance should have to cover dental care too for all non-cosmetic procedures-- especially if there is an infection or risk of one.
area51
(11,913 posts)and it's yet another reason why we need single-payer/comprehensive Medicare for All.
SoCalDem
(103,856 posts)and vision care.. You can pay extra , but many people who only get SS and a small pension, cannot afford it, so they do without.. Not surprising that dental issues have other consequences.. Heart disease is sometimes connected to dental issues..
Liberal In Texas
(13,559 posts)...and should be.
Poor dental hygiene can cause:
Cardiovascular Disease.
Dementia. Poor oral health can affect the brain. ...
Respiratory Infections. ...
Diabetes. ...
Pregnancy Complications. ...
Infertility. ...
Erectile Dysfunction. ...
Cancer.
https://www.absolutedental.com/blog/10-health-issues-caused-by-bad-oral-health/
McCamy Taylor
(19,240 posts)Tree-Hugger
(3,370 posts).....is very messed up. Your dental health affects your overall health, but dental insurance in America is an absolute joke.
This morning I just had one tooth worked on. It has a temp crown right now as I await a root canal in a few weeks. Between today's appointment, the root canal, and the permanent crown, I will have used up 95% of my dental insurance allotment for the year. And it doesn't even cover anything (other than basic cleaning and dad's)100%. I still have $700 out of pocket for one tooth.
I could go on and on about everything wrong with the system. Also, fuck Trump.
Liberal In Texas
(13,559 posts)And I also just had to have a root canal and a crown. Cost a fortune, but the insurance wouldn't have paid much anyway.
If one has it through employment it's bad enough.
Dave Starsky
(5,914 posts)Is vastly underrated . It should be more focused on.
There are veins and sinuses in the head that are difficult to
treat.