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LiberalArkie

(15,716 posts)
Wed Jun 24, 2020, 08:01 PM Jun 2020

Type of ultraviolet light kills airborne coronavirus; effect on platelets helps explain blood clot i

Type of ultraviolet light kills airborne coronavirus; effect on platelets helps explain blood clot issues

-Snip-

Safe form of ultraviolet light kills airborne coronavirus

Ceiling fixtures emitting a safe form of ultraviolet light called far-UVC would be very efficient at killing airborne coronaviruses, according to a study by researchers at Columbia University. "A very low exposure to far-UVC light killed well over 99.9% of the exposed virus," lead researcher Dr. David Brenner told Reuters. The researchers put coronavirus particles into little droplets and floated them in the air in front of far-UVC lights, then collected the viruses and tested them to see how many were still active. The study, published on Wednesday in Scientific Reports, used coronaviruses that cause common colds. "But in our subsequent ongoing studies we have found that the coronavirus that causes COVID-19 is killed in just the same way by far-UVC light," Brenner said. The idea would be to install overhead far-UVC lights in public locations, where they would be "continuously killing microbes, including the COVID-19 virus - and so limiting the spread of the virus," Brenner said, adding that far-UVC manufacturers are already ramping up production. "We don't see far-UVC light as an alternative to masks and social distancing," Brenner said. "We see it as a new extra weapon that we can use in the battle against COVID-19." (go.nature.com/3hYdWYA)

https://www.nature.com/articles/s41598-020-67211-2
=Snip

Cells that help blood to clot over-activated by the coronavirus

The effect of the new coronavirus on platelets in the blood may help explain the excessive blood clotting that has led to serious complications and strokes in some COVID-19 patients. It is the job of platelets to recognize wounds and prevent bleeding by forming clots. They also recruit immune cells and generate inflammation. On Tuesday, researchers reported in the journal Blood that the new coronavirus drastically changes platelet gene expression and function. The inflammatory proteins generated by the virus cause platelets to become "hyperreactive" and form clots more easily and more often, coauthor Robert Campbell of the University of Utah told Reuters. The effect was correlated with patient illness severity, his team found. In a separate not-yet-peer-reviewed study, researchers found that platelets in 20% of COVID-19 patients contain molecules with the genetic code of the coronavirus. It is not clear yet whether the virus actually targets the platelets, or if the platelets contain the full virus, said study coauthor Eric Boilard of Universitaire de Québec. "What was very obvious was the impressive level of platelet activation in COVID-19," Boilard said. The findings may open up new avenues to treat clot related complications in COVID-19. (bit.ly/2Z3pj8Z; bit.ly/2B6Zmx9)

https://ashpublications.org/blood/article/doi/10.1182/blood.2020007214/461106/Platelet-Gene-Expression-and-Function-in-COVID-19
https://www.medrxiv.org/content/10.1101/2020.06.23.20137596v1

Snip

https://www.reuters.com/article/us-health-coronavirus-science/type-of-ultraviolet-light-kills-airborne-coronavirus-effect-on-platelets-helps-explain-blood-clot-issues-idUSKBN23V2VP
48 replies = new reply since forum marked as read
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Type of ultraviolet light kills airborne coronavirus; effect on platelets helps explain blood clot i (Original Post) LiberalArkie Jun 2020 OP
Very Good Article ProfessorGAC Jun 2020 #1
Very good news.. Once those lamps are every where, colds and the flu may be a thing of the past LiberalArkie Jun 2020 #2
Far uV Is Pretty Innocuous ProfessorGAC Jun 2020 #8
But for how long can a human be subjected to it without having problems? LisaL Jun 2020 #13
It's Exponential To MEv ProfessorGAC Jun 2020 #23
I have a 4ft fixture with 2 black light bulbs. safeinOhio Jun 2020 #20
It Might ProfessorGAC Jun 2020 #24
No, black lights are UV; any visible light is "leakage" due to the spectral width of the source. lagomorph777 Jun 2020 #30
Belaboring The Obvious ProfessorGAC Jun 2020 #42
A Vaseline collection under black lights? Do tell? lagomorph777 Jun 2020 #31
LOL...I second that! n/t OneGrassRoot Jun 2020 #32
Vaseline glass, or uranium glass fluoresces under UV light. aidbo Jun 2020 #37
I don't know but StarryNite Jun 2020 #34
It was pretty cool. safeinOhio Jun 2020 #39
They're using 222 nm UV, shorter wavelenghth than UVA, UVB, and most UVC n/t sl8 Jun 2020 #26
That's Not Very Far uV ProfessorGAC Jun 2020 #41
A few corrections lagomorph777 Jun 2020 #33
I Didn't See uVc In The Article ProfessorGAC Jun 2020 #40
Far UV is 122 nm to 200 nm. sl8 Jun 2020 #44
My understanding of "near" and "far" is the same as yours. lagomorph777 Jun 2020 #45
"A very low exposure to far-UVC light killed well over 99.9% of the exposed virus," lagomorph777 Jun 2020 #46
Thank you, LA! SheltieLover Jun 2020 #3
These are both fascinating articles. Thanks for sharing them. n/t CaliforniaPeggy Jun 2020 #4
As an aspie, it is thing in life to get over obsessive in researching topics LiberalArkie Jun 2020 #9
it is happening LiberalArkie Jun 2020 #5
Note that these lights are not the "human safe" ones referenced in your OP. sl8 Jun 2020 #28
I think the ones they currently make are the powerful ones. LiberalArkie Jun 2020 #29
Quick...! UncleTomsEvilBrother Jun 2020 #6
Do we have any idea Sgent Jun 2020 #7
No ill effects at all according to experts LiberalArkie Jun 2020 #10
Even for those with lupus? Did they say? marybourg Jun 2020 #12
I think a person would have to test themselves LiberalArkie Jun 2020 #17
Thanks. I may have to go into permanent shelter in place. marybourg Jun 2020 #18
No direct mention of lupus, but the wavelength they are talking about doesn't penetrate the dead LiberalArkie Jun 2020 #27
Thanx! marybourg Jun 2020 #35
I don't think so. LisaL Jun 2020 #14
See Post 8 ProfessorGAC Jun 2020 #11
Thanks, LiberalArkie! Very informative articles - good stuff to know! BComplex Jun 2020 #15
Thank you! This is another reason why DU rocks! Buckeye_Democrat Jun 2020 #16
Great info - thanks, LiberalArkie. nt crickets Jun 2020 #19
So: dumb question, perhaps, but could sunlight have a similar effect? Mister Ed Jun 2020 #21
Drumpf's going to propose that light in the body thing again soothsayer Jun 2020 #22
Why they think this type of UVC is safer (for humans) than currently used germicidal UVC: sl8 Jun 2020 #25
But if sunlight can cause sunburn ... Tennessee Hillbilly Jun 2020 #36
Yes sunlight does kill it, very fast from what I have read. That is why so far not that many LiberalArkie Jun 2020 #38
Shipments of both butt plugs and mouth gag versions shipping to 1600.... SOONISH? Brainfodder Jun 2020 #43
Kick Uv burrowowl Jun 2020 #47
The journal "Blood." Maru Kitteh Jun 2020 #48

ProfessorGAC

(65,057 posts)
8. Far uV Is Pretty Innocuous
Wed Jun 24, 2020, 08:09 PM
Jun 2020

It's only 20 to 60 nanometers shorter wavelength than purple light.
It won't, except in very specific conditions, cause free radical formation, except for ozone.
It doesn't absorb into the skin much differently than visible light.
And, it's not hard on the eyes like uVa or uVb.
I hope this study pans out.

LisaL

(44,973 posts)
13. But for how long can a human be subjected to it without having problems?
Wed Jun 24, 2020, 08:22 PM
Jun 2020

I don't think they know. They are already using UV-C robots to clean hospital rooms, but humans have to leave first.

ProfessorGAC

(65,057 posts)
23. It's Exponential To MEv
Thu Jun 25, 2020, 05:51 AM
Jun 2020

Far uV is more than 10x lower photon intensity than uVb, nearly 1.25th of uVa.
Exposure goes up on a quadratic curve as photon intensity goes down.
I think they know more about the safety of far uV than you suggest.

safeinOhio

(32,686 posts)
20. I have a 4ft fixture with 2 black light bulbs.
Wed Jun 24, 2020, 09:03 PM
Jun 2020

Use to display a Vaseline glass collection. Would it work?

ProfessorGAC

(65,057 posts)
24. It Might
Thu Jun 25, 2020, 05:55 AM
Jun 2020

Black light, by definition, is visible light. We can see it, right?
The uV present is very far uV. Just the non visible wavelengths down from purple.
It's basically ranging from blue to slightly ultraviolet.
I don't know that it's true uVc. Not only the photon energy state, but percentage of very far uV might be very low.
Overall intensity may not be enough.

lagomorph777

(30,613 posts)
30. No, black lights are UV; any visible light is "leakage" due to the spectral width of the source.
Thu Jun 25, 2020, 11:06 AM
Jun 2020

The physicist's definition of "light" includes everything from extremely low frequency radio waves to high energy gamma rays.

ProfessorGAC

(65,057 posts)
42. Belaboring The Obvious
Thu Jun 25, 2020, 01:59 PM
Jun 2020

Do you see it?
Yes.
Then there's visible light. Leakage or not, it's still visible light.
I don't need anybody to tell there are different frequencies of light.
Ridiculous of you to presume so.
We were talking about two different phenomena.
If I misinterpreted the original information, that's on me.
But, we are talking about different things

ProfessorGAC

(65,057 posts)
41. That's Not Very Far uV
Thu Jun 25, 2020, 01:50 PM
Jun 2020

I misinterpreted the device. Because they mentioned "no I'll effects" I incorrectly assumed very far uV.
Not sure I agree 222nm can be said to have no I'll effects.

lagomorph777

(30,613 posts)
33. A few corrections
Thu Jun 25, 2020, 11:16 AM
Jun 2020
https://www.researchgate.net/profile/Patrick_Rochette/publication/235385802/figure/fig2/AS:299636834226181@1448450396234/Emission-spectrum-of-the-di-ff-erent-UV-lamps-UVA-UVB-and-UVC-irradiations-were.png

UVC is about 150 nanometers shorter than violet visible light. The energy in each photon is inversely proportional to its wavelength, so a UVC photon is 1.4x as energetic as a UVA photon, or 1.5x as energetic as a violet photon.

Though sunlight at Earth's surface has most UVC photons filtered out by the ozone layer, mercury lamps (i.e. a fluorescent tube, minus the white coating) generate copious UVC photons; these are used as germicidal lamps and tanning bed lamps, and they do cause skin cancer and eye damage if exposure is high.

ProfessorGAC

(65,057 posts)
40. I Didn't See uVc In The Article
Thu Jun 25, 2020, 01:48 PM
Jun 2020

Maybe I missed it. It mentions distant ultraviolet. I don't think they're the same thing.
Very far uV is in the 300s nanometers. Violet light is 400-410nm.
It's used in various multiband chemical analyses because water is more transparent to very far uV than for midband uV which is VERY common in chromatography. That's 254nm. Industry standard for organic analysts.
I don't think we're talking about the same thing.
On Edit:
Visible light is about 1.25 EV. Near ultraviolet is 12.4eV. How is that 1.8x?

sl8

(13,781 posts)
44. Far UV is 122 nm to 200 nm.
Thu Jun 25, 2020, 02:15 PM
Jun 2020

Near UV, adjacent to the visible spectrum, is from 300 nm to 400 nm.

http://www.spacewx.com/pdf/SET_21348_2004.pdf

On edit:

The researchers in the OP link must be using a slghtly different definition than the ISO 21348 d.efinitions. According to the latter, 222 is not far UV, although it's close.

Neither is close to the visible spectrum, that would be near UV.

lagomorph777

(30,613 posts)
45. My understanding of "near" and "far" is the same as yours.
Thu Jun 25, 2020, 02:40 PM
Jun 2020

"Nearly visible" and "far from visible" are the way I think of it.

lagomorph777

(30,613 posts)
46. "A very low exposure to far-UVC light killed well over 99.9% of the exposed virus,"
Thu Jun 25, 2020, 02:49 PM
Jun 2020

I calculate 3.1eV for 400nm violet light and 6.2eV for 200nm UVc

sl8

(13,781 posts)
28. Note that these lights are not the "human safe" ones referenced in your OP.
Thu Jun 25, 2020, 10:52 AM
Jun 2020

One of the companies even specifically ruled them out:


[..]

One technology that Osram has ruled out, however, is “far UV-C”, which is even shorter-wavelength UV light. Some believe it can be a safer light than UV-C while still killing viruses, and are examining it in particular at 222 nm. Its technology includes discharge sources as well as lasers. LESA’s Karlicek maintained that it won’t be suitable for LEDs.

[...]

LiberalArkie

(15,716 posts)
29. I think the ones they currently make are the powerful ones.
Thu Jun 25, 2020, 10:59 AM
Jun 2020

I am hoping that the 222nm LED's are possible to make cheaply..

Sgent

(5,857 posts)
7. Do we have any idea
Wed Jun 24, 2020, 08:09 PM
Jun 2020

what the long term effects of UV-C are? Its usually 100% blocked by the earth's atmosphere so we aren't exposed to it normally.

LiberalArkie

(15,716 posts)
17. I think a person would have to test themselves
Wed Jun 24, 2020, 08:37 PM
Jun 2020

Studies used to suggest that UVB rays -- the rays responsible for burning -- were most dangerous to people with lupus. But more recent research shows that UVA rays -- those responsible for wrinkling the skin -- can also aggravate lupus. With that in mind, you should look for broad-spectrum protection sunscreen that blocks both UVA and UVB rays.

LiberalArkie

(15,716 posts)
27. No direct mention of lupus, but the wavelength they are talking about doesn't penetrate the dead
Thu Jun 25, 2020, 10:47 AM
Jun 2020

skin layer of the body or even the layer of tears in the eye. Seems pretty safe. Here is a link to the latest in plain English.

https://www.democraticunderground.com/100213651055

ProfessorGAC

(65,057 posts)
11. See Post 8
Wed Jun 24, 2020, 08:11 PM
Jun 2020

Long wave uV has been used as a lab sanitizer for a while because it's safe.
The free radical formation piece is a big deal.

Buckeye_Democrat

(14,855 posts)
16. Thank you! This is another reason why DU rocks!
Wed Jun 24, 2020, 08:30 PM
Jun 2020

You're certainly not as likely to find helpful scientific information from a bunch of science-denying right-wingers, that's for sure!

Thanks again, LiberalArkie!

Mister Ed

(5,937 posts)
21. So: dumb question, perhaps, but could sunlight have a similar effect?
Wed Jun 24, 2020, 10:41 PM
Jun 2020

Sunlight would include these far UV rays in its spectrum, but would they be of sufficient intensity to match the artificial UV lights in these tests? Maybe someone smart here on DU will know.

sl8

(13,781 posts)
25. Why they think this type of UVC is safer (for humans) than currently used germicidal UVC:
Thu Jun 25, 2020, 07:19 AM
Jun 2020

[...]

Ultraviolet (UV) light exposure is a direct antimicrobial approach4 and its effectiveness against different strains of airborne viruses has long been established5. The most commonly employed type of UV light for germicidal applications is a low pressure mercury-vapor arc lamp, emitting around 254?nm; more recently xenon lamp technology has been used, which emits broad UV spectrum6. However, while these lamps can be used to disinfect unoccupied spaces, direct exposure to conventional germicidal UV lamps in occupied public spaces is not possible since direct exposure to these germicidal lamp wavelengths can be a health hazard, both to the skin and eye7,8,9,10.

By contrast far-UVC light (207 to 222?nm) has been shown to be as efficient as conventional germicidal UV light in killing microorganisms11, but studies to date12,13,14,15 suggest that these wavelengths do not cause the human health issues associated with direct exposure to conventional germicidal UV light. In short (see below) the reason is that far-UVC light has a range in biological materials of less than a few micrometers, and thus it cannot reach living human cells in the skin or eyes, being absorbed in the skin stratum corneum or the ocular tear layer. But because viruses (and bacteria) are extremely small, far-UVC light can still penetrate and kill them. Thus far-UVC light potentially has about the same highly effective germicidal properties of UV light, but without the associated human health risks12,13,14,15. Several groups have thus proposed that far-UVC light (207 or 222?nm), which can be generated using inexpensive excimer lamps, is a potential safe and efficient anti-microbial technology12,13,14,15,16,17,18 which can be deployed in occupied public locations.

The biophysically-based mechanistic basis to this far-UVC approach12 is that light in this wavelength range has a very limited penetration depth. Specifically, far-UVC light (207–222?nm) is very strongly absorbed by proteins through the peptide bond, and other biomolecules19,20, so its ability to penetrate biological materials is very limited compared with, for example, 254?nm (or higher) conventional germicidal UV light21,22. This limited penetration is still much larger than the size of viruses and bacteria, so far-UVC light is as efficient in killing these pathogens as conventional germicidal UV light12,13,14. However, unlike germicidal UV light, far-UVC light cannot penetrate either the human stratum corneum (the outer dead-cell skin layer), nor the ocular tear layer, nor even the cytoplasm of individual human cells. Thus, far-UVC light cannot reach or damage living cells in the human skin or the human eye, in contrast to the conventional germicidal UV light which can reach these sensitive cells7,8,9,10.

In summary far-UVC light is anticipated to have about the same anti-microbial properties as conventional germicidal UV light, but without producing the corresponding health effects. Should this be the case, far-UVC light has the potential to be used in occupied public settings to prevent the airborne person-to-person transmission of pathogens such as coronaviruses

[...]

36. But if sunlight can cause sunburn ...
Thu Jun 25, 2020, 11:47 AM
Jun 2020

and this artificial uv doesn't, then it seems to me that sunlight would be able to kill this virus.

LiberalArkie

(15,716 posts)
38. Yes sunlight does kill it, very fast from what I have read. That is why so far not that many
Thu Jun 25, 2020, 12:04 PM
Jun 2020

protesters have gotten it outside. Maybe in the jail though.

Brainfodder

(6,423 posts)
43. Shipments of both butt plugs and mouth gag versions shipping to 1600.... SOONISH?
Thu Jun 25, 2020, 02:04 PM
Jun 2020

Death Count Donnie needs protection!

Maru Kitteh

(28,340 posts)
48. The journal "Blood."
Fri Jun 26, 2020, 01:40 AM
Jun 2020

I'm a huge medical nerd that reads medical nerd things all day long and I gotta say . . . . . . Blood?

It's a kinda creepy (or at the very least, unimaginative) title.


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