General Discussion

SheltieLover

(57,073 posts) Wed Aug 12, 2020, 01:44 PM Aug 2020

Scientists Think They Found the Coronavirus' Weak Spot

https://futurism.com/found-coronavirus-weak-spot/amp

Scientists think they’ve identified a weak point in SARS-CoV-2, the coronavirus that causes COVID-19. And just like shooting torpedoes down the Death Star’s exhaust shaft, they think they can exploit this critical weakness to make new treatments.

It all comes down to a tiny region right next to the virus’s spike proteins, which latch onto new host cells, according to research published last week in the journal ACS Nano. Explaining the weakness requires a little bit of a primer on biochemistry, so bear with us, but the Northwestern University scientists suggest targeting this weak point could render the virus inert.

Much more at link. 🤞🤞🤞🤞🤞

26 replies

= new reply since forum marked as read

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Scientists Think They Found the Coronavirus' Weak Spot (Original Post) SheltieLover Aug 2020 OP

This message was self-deleted by its author Sherman A1 Aug 2020 #1

I sure hope so, Sherman! SheltieLover Aug 2020 #2

Wrong concept. Will lead to treatments. Vaccines teach the immune system to recognize. Bernardo de La Paz Aug 2020 #17

Gosh, I'm sorry. Sherman A1 Aug 2020 #18

No you are not stupid. Don't play the victim just because you got corrected. Learn & move on. Bernardo de La Paz Aug 2020 #19

Bye Sherman A1 Aug 2020 #23

Don't feel stupid, Sherman SheltieLover Aug 2020 #26

Sounds promising Bayard Aug 2020 #3

Yes, of course! SheltieLover Aug 2020 #4

Cool! Should work for all types of coronavirus then? soothsayer Aug 2020 #5

Dunno, but we can hope! SheltieLover Aug 2020 #6

Probably not. progressoid Aug 2020 #11

Ah. Still could lead to future solutions maybe soothsayer Aug 2020 #15

If Digger Aug 2020 #7

King of Orange,... see,... see,... see,... I told you it would just disappear,... magicarpet Aug 2020 #8

Corona virus has certainly found humanity's weak point. Midnight Writer Aug 2020 #9

It sure has! SheltieLover Aug 2020 #12

Republicans Mr.Bill Aug 2020 #16

👍 SheltieLover Aug 2020 #24

The last sentence was a bummer. ananda Aug 2020 #10

Ikr? SheltieLover Aug 2020 #13

May the force be with them. dbonds Aug 2020 #14

I won't accept anything trump suggests. rickyhall Aug 2020 #20

Ain't it odd Politicalgolfer Aug 2020 #21

Yup SheltieLover Aug 2020 #25

I love the Starwars analogy... Short and sweet.. nt mitch96 Aug 2020 #22

Response to SheltieLover (Original post)

Sherman A1 This message was self-deleted by its author.

SheltieLover

(57,073 posts)

2. I sure hope so, Sherman!

Reply to Sherman A1 (Reply #1)

Wed Aug 12, 2020, 01:48 PM

Aug 2020

🤞🤞🤞🤞🤞🤞

Bernardo de La Paz

(49,043 posts)

17. Wrong concept. Will lead to treatments. Vaccines teach the immune system to recognize.

Reply to Sherman A1 (Reply #1)

Wed Aug 12, 2020, 04:09 PM

Aug 2020

If the immune system could exploit such a weakness, it would be exploiting it already and Covid would truly be less than influenza and more like a cold.

The trick for vaccines is to have the immune system primed so that as soon as virus particles show up the immune system says "I know you! I know what to do about you!"

This would be more exploitable for treatment.

The article mentions treatment but not vaccine.

Sherman A1

(38,958 posts)

18. Gosh, I'm sorry.

Reply to Bernardo de La Paz (Reply #17)

Wed Aug 12, 2020, 04:12 PM

Aug 2020

I will remove my comment as I am stupid.

Bernardo de La Paz

(49,043 posts)

19. No you are not stupid. Don't play the victim just because you got corrected. Learn & move on.

Reply to Sherman A1 (Reply #18)

Wed Aug 12, 2020, 04:16 PM

Aug 2020

Gosh, we all make mistakes!

Sherman A1

(38,958 posts)

23. Bye

Reply to Bernardo de La Paz (Reply #19)

Wed Aug 12, 2020, 04:22 PM

Aug 2020

SheltieLover

(57,073 posts)

26. Don't feel stupid, Sherman

Reply to Sherman A1 (Reply #18)

Wed Aug 12, 2020, 04:26 PM

Aug 2020

I don't understand a lot of this either.

Bayard

(22,153 posts)

3. Sounds promising

Reply to SheltieLover (Original post)

Wed Aug 12, 2020, 01:48 PM

Aug 2020

But a long time making it viable.

SheltieLover

(57,073 posts)

4. Yes, of course!

Reply to Bayard (Reply #3)

Wed Aug 12, 2020, 01:50 PM

Aug 2020

Inspires hope, though. 🤞🤞🤞

soothsayer

(38,601 posts)

5. Cool! Should work for all types of coronavirus then?

Reply to SheltieLover (Original post)

Wed Aug 12, 2020, 01:50 PM

Aug 2020

Bye, common cold!

SheltieLover

(57,073 posts)

6. Dunno, but we can hope!

Reply to soothsayer (Reply #5)

Wed Aug 12, 2020, 01:52 PM

Aug 2020

progressoid

(49,999 posts)

11. Probably not.

Reply to soothsayer (Reply #5)

Wed Aug 12, 2020, 03:48 PM

Aug 2020

Each subunit of the SARS-CoV-2 trimeric spike protein has one polybasic cleavage site (R682RAR685).(1) The polybasic cleavage sites (R682RAR685) have not been reported for SARS-CoV or any other lineage B coronaviruses, and therefore, they are thought to be unique to SARS-CoV-2.(2,15,16) In comparison to the extensive studies carried out on the SARS-CoV-2 RBD, the polybasic cleavage sites have thus far not been widely investigated, and their function remains elusive. They are believed to be related to the viral transmissibility of SARS-CoV-2.(2,16) Moreover, they have been found to be essential for spike protein-driven viral entry into lung cells.(17)

https://pubs.acs.org/doi/10.1021/acsnano.0c04798

soothsayer

(38,601 posts)

15. Ah. Still could lead to future solutions maybe

Reply to progressoid (Reply #11)

Wed Aug 12, 2020, 03:54 PM

Aug 2020

Digger

(478 posts)

7. If

Reply to SheltieLover (Original post)

Wed Aug 12, 2020, 02:13 PM

Aug 2020

If and when a cure is found, trump will take credit for it; and his troglodytes will again wallow in their stupidity.

magicarpet

(14,174 posts)

8. King of Orange,... see,... see,... see,... I told you it would just disappear,...

Reply to SheltieLover (Original post)

Wed Aug 12, 2020, 02:19 PM

Aug 2020

... and no deaths would happen.

If people would only listen to me !

Midnight Writer

(21,802 posts)

9. Corona virus has certainly found humanity's weak point.

Reply to SheltieLover (Original post)

Wed Aug 12, 2020, 03:33 PM

Aug 2020

SheltieLover

(57,073 posts)

12. It sure has!

Reply to Midnight Writer (Reply #9)

Wed Aug 12, 2020, 03:48 PM

Aug 2020

Trumputin virus!

Mr.Bill

(24,325 posts)

16. Republicans

Reply to Midnight Writer (Reply #9)

Wed Aug 12, 2020, 03:56 PM

Aug 2020

SheltieLover

(57,073 posts)

24. 👍

Reply to Mr.Bill (Reply #16)

Wed Aug 12, 2020, 04:22 PM

Aug 2020

ananda

(28,876 posts)

10. The last sentence was a bummer.

Reply to SheltieLover (Original post)

Wed Aug 12, 2020, 03:36 PM

Aug 2020

Figuring all this out wil be "time consuming
and tricky work."

Oh well.

SheltieLover

(57,073 posts)

13. Ikr?

Reply to ananda (Reply #10)

Wed Aug 12, 2020, 03:49 PM

Aug 2020

At least they say they will make it low cost & otc! 🤞🤞🤞

dbonds

(4,793 posts)

14. May the force be with them.

Reply to SheltieLover (Original post)

Wed Aug 12, 2020, 03:51 PM

Aug 2020

rickyhall

(4,889 posts)

20. I won't accept anything trump suggests.

Reply to SheltieLover (Original post)

Wed Aug 12, 2020, 04:16 PM

Aug 2020

But after Mr. Biden takes over I have no problem.

Politicalgolfer

(317 posts)

21. Ain't it odd

Reply to SheltieLover (Original post)

Wed Aug 12, 2020, 04:17 PM

Aug 2020

Ain't it odd that Republicans, who preach that science is a hoax & scientific reports are fake news, are investing in stocks in companies working on a vaccine & pushing for warp speed results to save their unholy asses! They slash funding for scientific research but will bust a gut trying to take the credit for any scientific success.

SheltieLover

(57,073 posts)

25. Yup

Reply to Politicalgolfer (Reply #21)

Wed Aug 12, 2020, 04:23 PM

Aug 2020

Greedy fockers.

mitch96

(13,924 posts)

22. I love the Starwars analogy... Short and sweet.. nt

Reply to SheltieLover (Original post)

Wed Aug 12, 2020, 04:20 PM

Aug 2020

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