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My mom has been diagnosed with myeloprodysplastic/myeloproliferative hyperplasia unclassifiable (Original Post) peacebird Nov 2012 OP
Sounds like leukemia/pre-leukemia to me, but not a doc marybourg Nov 2012 #1
Well - I'm a middle-aged guy who just got a nursing degree and then passed the RN exam ... codjh9 Nov 2012 #2
Bone marrow abnormality. Pre-leukemia. Laffy Kat Nov 2012 #6
Mom is 84 and has a white blood cell count of 93, when about 10 is normal.... peacebird Nov 2012 #9
Yeah, the high white blood cell count would fit. However, although I can't remember which codjh9 Nov 2012 #10
I wonder if the drug was Imatinib? Science Geek Nov 2012 #17
I don't think so - I think if you'd said the one his mom is on, I'd recognize it ... but then again, codjh9 Nov 2012 #18
Mom was given the drug hydroxyurea (hydrea) peacebird Nov 2012 #19
IDK, but my prayers are with you and her panAmerican Nov 2012 #3
If it's leukemia, I'm so sorry. But my stepmother (age 70ish) has leukemia.... Honeycombe8 Nov 2012 #4
That's actually wonderful to hear! peacebird Nov 2012 #20
Yes, take heart. She actually feels okay. Honeycombe8 Nov 2012 #21
according to google BlueToTheBone Nov 2012 #5
A tumor in a muscle from what I can locate,,, I am sorry benld74 Nov 2012 #7
What were her symptoms? What persuaded her to go to the doctor? nt Laffy Kat Nov 2012 #8
The high white blood cell count was found in hospital last Januarynafter her bout with bronchitis peacebird Nov 2012 #11
Incidental finding, so the pneumonia might have been a blessing in disguise. Laffy Kat Nov 2012 #15
Peacebird, no medical knowledge, but sending prayers/good thoughts for both of you. PATXgirl Nov 2012 #12
Sorry to hear your news 2theleft Nov 2012 #13
Ok just went to the medical online dictionary nadinbrzezinski Nov 2012 #14
My 84 yr old dad has something similar...low platelet production. cry baby Nov 2012 #16

codjh9

(2,781 posts)
2. Well - I'm a middle-aged guy who just got a nursing degree and then passed the RN exam ...
Mon Nov 5, 2012, 09:59 PM
Nov 2012

so I know a fair amount, but a doctor or an experienced RN would know more. In any case, a quick lookup showed that you can probably leave the 'pro' off of the first word/term. It appears to be some type of unusual pre-leukemia state, but again, I say 'appears' since you didn't include another word I found in searching, which was 'erythropoetic' before the hyperplasia. Erythropoetin is involved in the formation of red blood cells, and hyperplasia usually means an abnormal rate or size of growth.

(Correct me or add to this, anyone else?)

And let me just add that a) I hope it doesn't go into leukemia, and b) either way, I wish your mom a full recovery.

peacebird

(14,195 posts)
9. Mom is 84 and has a white blood cell count of 93, when about 10 is normal....
Mon Nov 5, 2012, 10:08 PM
Nov 2012

The oncologist said he had never seen a case where this happened... As I understand it, normally one of three would be low; either white blood cells, red, pllatelets.

In moms case none were true. She has normal red and platelets, plus exceedingly high white blood cells.
Heres hoping UVA can find a solution.

codjh9

(2,781 posts)
10. Yeah, the high white blood cell count would fit. However, although I can't remember which
Mon Nov 5, 2012, 10:11 PM
Nov 2012

type of leukemia this was, nor the drug, but a friend's mother benefited from a drug that was released from testing just in time to save her life, literally, several years ago, and she's still on it, and still doing well. 'They' can cure or push into remission (for years) some types of leukemia now that were previously not curable. Again, hoping for the best.

Science Geek

(161 posts)
17. I wonder if the drug was Imatinib?
Mon Nov 5, 2012, 11:39 PM
Nov 2012

The FDA has approved imatinib for use in adult patients with relapsed or refractory Ph-positive ALL, myelodysplastic/myeloproliferative diseases associated with platelet-derived growth factor receptor gene re-arrangements, aggressive systemic mastocytosis (ASM) without or an unknown D816V c-KIT mutation, hypereosinophilic syndrome (HES) and/or chronic eosinophilic leukemia (CEL) who have the FIP1L1-PDGFR? fusion kinase (CHIC2 allele deletion) or FIP1L1-PDGFR? fusion kinase negative or unknown, unresectable, recurrent and/or metastatic dermatofibrosarcoma protuberans.[

http://en.wikipedia.org/wiki/Imatinib

codjh9

(2,781 posts)
18. I don't think so - I think if you'd said the one his mom is on, I'd recognize it ... but then again,
Mon Nov 5, 2012, 11:50 PM
Nov 2012

I can't remember everything. :^)

peacebird

(14,195 posts)
19. Mom was given the drug hydroxyurea (hydrea)
Tue Nov 6, 2012, 06:17 AM
Nov 2012

It is supposed to bring her WBC down. Is that the drug she used?

Honeycombe8

(37,648 posts)
4. If it's leukemia, I'm so sorry. But my stepmother (age 70ish) has leukemia....
Mon Nov 5, 2012, 10:01 PM
Nov 2012

stage 4. Doctor says it's manageable, and she'll die of old age before the leukemia does her in.

Honeycombe8

(37,648 posts)
21. Yes, take heart. She actually feels okay.
Tue Nov 6, 2012, 07:35 AM
Nov 2012

She has to stay away from a lot of people, since her immune systsem is weakened, and she can't risk picking up an illness.

She goes out of town occasionally for some sort of treatment (is it radiation? I forget), but the treatment does NOT make her sick, thank goodness.

She is religious, so there's that. But she has the attitude that it could be worse. She could be in pain, or it could be the kind of cancer that would kill her soon. I don't know what my father would do if she passed away. I was suprised when she told me that it wouldn't kill her. That's probably because of her age....she'll die from other things, incl. natural causes, before the leukemia gets her. The dr told her she could live easily for 20 years with the cancer and manage it. It may depend on the particular KIND of leukemia she has. I don't know. But medicine has made such advances in the treatment of cancer.

She's lucky, most of all, to have YOU!

BlueToTheBone

(3,747 posts)
5. according to google
Mon Nov 5, 2012, 10:02 PM
Nov 2012

preleukemia and hodgkins disease. Serious stuff. Sorry to be the bearer of this unhappy news.

These bodies are so temporary and such traitors...just as we become comfortable in them, they change and decay. May we all become enlightened in our lifetime.
Om Mani Padme Hum

peacebird

(14,195 posts)
11. The high white blood cell count was found in hospital last Januarynafter her bout with bronchitis
Mon Nov 5, 2012, 10:15 PM
Nov 2012

And pneumonia.

Laffy Kat

(16,383 posts)
15. Incidental finding, so the pneumonia might have been a blessing in disguise.
Mon Nov 5, 2012, 11:23 PM
Nov 2012

My positive thoughts your mom's way, peacebird.

2theleft

(1,136 posts)
13. Sorry to hear your news
Mon Nov 5, 2012, 10:32 PM
Nov 2012

But, I do have high hopes for her at UVA. My good friends mom was there last year this time for a very scary illness and she is now on in recovery. The hospital was wonderful to both her and the family, so I hope you have all have a similar experience.

Your family is in my thoughts. Sending good vibes to you!!

 

nadinbrzezinski

(154,021 posts)
14. Ok just went to the medical online dictionary
Mon Nov 5, 2012, 10:41 PM
Nov 2012

here is a good link you might want to read.

Essentially these are bone marrow issues, that lead to

Myelodysplastic syndromes (MDS) represent a group of myeloid (bone marrow) stem cell disorders that gradually affect the ability of a person's bone marrow to produce normal red blood cells, white blood cells, and platelets.


http://www.myelodysplastic-info.com/2009/landinge.php?gid=HM017&?a=a&assoc=Google&keyword=myelodysplasticsyndromes

Good luck to your mom and you. It is a hard road to hoe. My aunt had one of those many decades ago, I hope research and science has improved all that.

cry baby

(6,682 posts)
16. My 84 yr old dad has something similar...low platelet production.
Mon Nov 5, 2012, 11:34 PM
Nov 2012

Bone marrow, pre-leukemia type disease. He is doing 5 straight days every month of chemo. I've left family in Tn to live with him and my 85 yr old mother in Tx. Chemo weeks are bad, but his numbers are up. After 4 months of chemo, he is stable in a normal range of platelets.

I hope your mom has as good a result with her treatment as my dad has! Hang in...and tell your mom to do the same! Keep smiling, it can get better. From the bottom of my heart, I wish your mom the very best of luck!

I did come home to Tn to vote!! I go back to Tx on Thursday.

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