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eridani

(51,907 posts)
Sun Mar 10, 2013, 10:04 AM Mar 2013

New Study: Vaporized Marijuana is a Safe and Effective Pain Treatment

Another in the growing pile of studies.

http://www.nationofchange.org/new-study-vaporized-marijuana-safe-and-effective-pain-treatment-1362844519

This latest study was conducted by researchers at the University of California Davis Medical Center and was published in The Journal of Pain. It was a double blind, placebo-controlled, crossover study that looked at the effectiveness of using vaporized, inhaled cannabis in 39 participants. These participants were experiencing neuropathic pain despite having tried traditional treatments (like opiate drugs). All participants continued to take their prescribed medications throughout the four-week study period.

Researchers gave participants doses of cannabis with moderate THC levels (3.53 percent) or low THC levels (1.29 percent). (THC, or tetrahydrocannabinol, is the plant’s primary psychoactive chemical). Some also received a placebo with no THC. They found both doses of cannabis to be effective in reducing pain significantly.

“Both the low and medium doses proved to be salutary analgesics for the heterogeneous collection of neuropathic pain conditions studied. Both active study medications provided statistically significant 30percent reductions in pain intensity when compared to placebo,” stated the researchers.
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New Study: Vaporized Marijuana is a Safe and Effective Pain Treatment (Original Post) eridani Mar 2013 OP
odd that the article mentions only mentions thc levels independentpiney Mar 2013 #1
Perhaps the author of this article Cirque du So-What Mar 2013 #5
I don't think that's the case though I'm not an expert but Voice for Peace Mar 2013 #8
I think you must be correct. sofa king Mar 2013 #14
No, I think there's an inverse relationship. Comrade Grumpy Mar 2013 #18
THC and CBD levels rise or fall proportionate to the other cannabinoid RainDog Mar 2013 #19
I think they made the point that low THC levels made no difference to the eridani Mar 2013 #24
That's good news alfredo Mar 2013 #2
Interesting. I wish it had worked for me. kag Mar 2013 #3
it's possible you just didn't have the right strains Voice for Peace Mar 2013 #10
I thought of that. kag Mar 2013 #12
Did you try eating it-especially good for sleep. roody Mar 2013 #22
Pay attention to Voice for Peace. The strain matters eridani Mar 2013 #25
Well, I'm certainly willing to try it again... kag Mar 2013 #30
Unfortunately, no medication works for everyone. mucifer Mar 2013 #26
But if it's not made by a large pharmaceutical company can it really work? mountain grammy Mar 2013 #4
"Vaporized marijuana"? But, smokin' pot'll turn you into a sex maniac. leveymg Mar 2013 #6
Sounds good to me... formercia Mar 2013 #9
DU Rec Tuesday Afternoon Mar 2013 #7
Vaporized as in 'pass the bong?' tinrobot Mar 2013 #11
Not exactly. kag Mar 2013 #13
NO, vapor as in heat until you create *steam* eggplant Mar 2013 #15
Like an e-cig, it sounds like... Buns_of_Fire Mar 2013 #21
And some look like that, too. eggplant Mar 2013 #23
Vaporized like asthma medicine in a nebulizer: mucifer Mar 2013 #27
Pharmaceutical corporates head seen exploding all over the country Smilo Mar 2013 #16
Opiates libodem Mar 2013 #17
antiseizure meds often work well for neuropathic pain and methadone works mucifer Mar 2013 #28
That is where the Lyrica comes in libodem Mar 2013 #29
Opiates as 'traditional treatment'... RedCappedBandit Mar 2013 #20

independentpiney

(1,510 posts)
1. odd that the article mentions only mentions thc levels
Sun Mar 10, 2013, 10:29 AM
Mar 2013

when cbd and other cannabinoids provide more of the pain relieving effects from what I've read.

Cirque du So-What

(25,939 posts)
5. Perhaps the author of this article
Sun Mar 10, 2013, 10:51 AM
Mar 2013

wanted to keep it simple for readers who may not be aware of the other cannabinoids that play a role in pain relief. I'm just shooting from the hip here, but is it possible that the level of other cannabinoids rises in proportion to higher levels of THC?

 

Voice for Peace

(13,141 posts)
8. I don't think that's the case though I'm not an expert but
Sun Mar 10, 2013, 11:06 AM
Mar 2013

I've had medical pot that was very high in CBD and low in THC
so there is very little 'high' but much other benefit.

sofa king

(10,857 posts)
14. I think you must be correct.
Sun Mar 10, 2013, 11:24 AM
Mar 2013

The other cannabinoids are effectively construction materials for making more THC, and when the plant is harvested production stops, leaving plenty of the construction materials lying around. I'm pretty sure there is a direct relationship between the level of THC and the proto-chemicals it uses to make THC. So if you have a plant that is very good at making THC, it must also have high levels of THC's attendant chemicals.

Those other cannabinoids are quite obviously powerful in their own right. For the better part of a year "fake weed" was for sale in convenience stores here in VA. It reputedly had no THC, but high concentrations of the other cannabinoids, and it worked astonishingly well, in my opinion, both as a pain reliever and as a euphoric.

As a guy who walks around with steel sutures in his genitals, sutures which expand and contract in the cold and which hold straining, twisting testicles in place so that I don't die, I really, really wish that the palliative effects of marijuana were acknowledged and accepted so that I could enjoy some relief as I did back in 2010 when such things were temporarily legal-like here. It is the only non-narcotic pain reliever I have ever found to actually work, aside from aspirin, which works about one-tenth as well.

 

Comrade Grumpy

(13,184 posts)
18. No, I think there's an inverse relationship.
Sun Mar 10, 2013, 02:20 PM
Mar 2013

The more THC, the less CBD.

For several decades now, people have been breeding for high THC because, well, it gets you high. So now, most pot grown here is high THC/low CBD, usually less than 1% CBD.

In recent years, breeders have begun breeding for higher CBD because of the perceived medical benefits. Now, in the better dispensaries, you can find high CBD products.

RainDog

(28,784 posts)
19. THC and CBD levels rise or fall proportionate to the other cannabinoid
Sun Mar 10, 2013, 03:05 PM
Mar 2013

there are many, many more cannabinoids that are still under study and most of them don't have a lot of info available yet. But if you have more THC, you have less CBD and vice versa. They also work two balance out the effects of one another. Not enough CBD and most people feel paranoid, for instance, for a period of time.

CBD is the cannabinoid that has been studied for many applications in cancer and diseases related to inflammation. IBS, arthritis, etc.

It's also the cannabinoid that was used to shrink brain tumors in studies in both animals and humans (whose brain cancer was most definitely already terminal...but it did shrink those tumors.)

Immediately after cannabis is consumed, the THC begins to break down into another cannabinoid that is the one that tells your brain you'd like to eat something tasty. Two to four hours after consuming cannabis, there is no more THC in your body. Instead, it has metabolized into other cannabinoids - and these are the ones that show up in drug tests - which is why urine tests, etc. are not valid tests for impairment.

eridani

(51,907 posts)
24. I think they made the point that low THC levels made no difference to the
Mon Mar 11, 2013, 06:02 AM
Mar 2013

--pain relief effect. This is relevant for people who don't care for the THC high--they can still use it for the diol content to get pain relief.

kag

(4,079 posts)
3. Interesting. I wish it had worked for me.
Sun Mar 10, 2013, 10:48 AM
Mar 2013

I've been a pain management patient for almost ten years now. When Colorado legalized medical marijuana, I got my "card" and tried it. I tried smoking it, but I don't smoke so it made me cough too much. Then I bought a vaporizer and tried it that way...several times.

I wish it had helped. I really wanted it too, because opiates are such a pain in the ass. Unfortunately, it really just made me feel kind of stupid and lose track of time. It also stunk up the house, and my husband hated it

But it didn't help with the pain. Not even a little. The most I could say is that it did get rid of some nausea when I tried for that, and it probably helped me sleep a little. But as for the pain (radicular nerve pain from my c-spine as well as Trigeminal Neuralgia in the maxillary nerve under my eye), it didn't touch it. I was bummed.

Glad it's working for others, though. Any ammunition to stop this idiotic "war" on drugs is fine with me.

 

Voice for Peace

(13,141 posts)
10. it's possible you just didn't have the right strains
Sun Mar 10, 2013, 11:09 AM
Mar 2013

after I got my card I realized how much variety there
is in effects, and also how people are not yet well
enough informed about what can help, and physicians
aren't either.. not enough time and research yet.

At any rate I wouldn't rule it completely out for the
future... good luck, pain sucks.

kag

(4,079 posts)
12. I thought of that.
Sun Mar 10, 2013, 11:22 AM
Mar 2013

But I really know almost nothing about mmj, and my docs were no help at all. They don't want to be. My family doc actually lost his DEA license after the CO law changed because he was handing out too many mmj cards. That's how the feds are "letting Colorado manage it themselves." When it was MMJ, they went after providers who were authorizing the cards, instead of the growers and distributors. Now that it's legal, hopefully he can work on getting his license back. (BTW, they made noises that it was all about something else, but it was really the MMJ.) So the docs are scared to even discuss it with their patients.

I asked the distributors I went to (and I tried a couple), but still didn't get much help from what they recommended.

Maybe now that things are changing, and more research is being done, I can try again with something that is more likely to help.

Thanks for the note and the encouragement. Pain, indeed, sucks.

eridani

(51,907 posts)
25. Pay attention to Voice for Peace. The strain matters
Mon Mar 11, 2013, 06:09 AM
Mar 2013

Nausea relief is a THC effect. There are way too many medical providers who have no clue about the actual THC and diol levels in their products. You want high diols and little THC for pain relief. Researchers are also paying more attention to gamma cannabinoids also.

kag

(4,079 posts)
30. Well, I'm certainly willing to try it again...
Mon Mar 11, 2013, 12:17 PM
Mar 2013

I did try eating it, but oddly, it seemed to upset my stomach. That could have been anomalous, but it still didn't do anything for the pain.

You're probably right about the strain. If I try it again I'll do a little more research. Thanks for the comments.

mucifer

(23,545 posts)
26. Unfortunately, no medication works for everyone.
Mon Mar 11, 2013, 09:38 AM
Mar 2013

Marijuana is just another medications that doctors use in their toolbox.

mountain grammy

(26,621 posts)
4. But if it's not made by a large pharmaceutical company can it really work?
Sun Mar 10, 2013, 10:50 AM
Mar 2013

In other words, if the lobbied interests can't make money off it, how can it possibly be legal?

kag

(4,079 posts)
13. Not exactly.
Sun Mar 10, 2013, 11:23 AM
Mar 2013

Bongs still burn it. Vaporizers heat it to the point of releasing the chemicals, but it doesn't burn. Cuts down on the irritants to the throat.

eggplant

(3,911 posts)
15. NO, vapor as in heat until you create *steam*
Sun Mar 10, 2013, 11:52 AM
Mar 2013

no smoke. none of the bad chemicals from burning it. just hot enough to convert the oils to a gas.

Buns_of_Fire

(17,180 posts)
21. Like an e-cig, it sounds like...
Sun Mar 10, 2013, 03:33 PM
Mar 2013

It always struck me that e-cigs (or "personal vaporizers", if you will) would be a pretty efficient way to administer some medications.

Smilo

(1,944 posts)
16. Pharmaceutical corporates head seen exploding all over the country
Sun Mar 10, 2013, 12:20 PM
Mar 2013

of course, those same heads will be working with their lobbyists and those on the Hill as to (a) how they can stop this, (b) how they can use this, and (c) how they can charge so much that most people won't be able to afford it.

And joining the pharmaceutical industry will be the lobbyists for private prisons.

libodem

(19,288 posts)
17. Opiates
Sun Mar 10, 2013, 01:21 PM
Mar 2013

Don't work all that well, on neuropathic pain. I have sciatica that terminates in the lateral edge of my left foot. It's similar to walking on a hot marble, just under my maleolus, that knob on your ankle. Lyrica tones it down a little. Betcha the wacky tabacky in a vaporized mist would be somewhat equivalent to my current cocktail. And more fun.

I gotsta find a less conservative state in which to reside. Ohhh, baby.

mucifer

(23,545 posts)
28. antiseizure meds often work well for neuropathic pain and methadone works
Mon Mar 11, 2013, 09:43 AM
Mar 2013

better than other narcotics but it's harder to dose and methadone is dirt cheap compared to other opiods.

libodem

(19,288 posts)
29. That is where the Lyrica comes in
Mon Mar 11, 2013, 11:45 AM
Mar 2013

It is similar to neurotin. The combination takes the edge off. I truely need to get back to the pool at the gym. That really improves everything especially my mood.

RedCappedBandit

(5,514 posts)
20. Opiates as 'traditional treatment'...
Sun Mar 10, 2013, 03:22 PM
Mar 2013

It really is absolutely hilarious... or it would be if it weren't so pathetic, that we are even having a discussion about the safety of marijuana while prescribing oxycodone and the like. Marijuana bad, but here's some legal heroin! Ridiculous.

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