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Related: Editorials & Other Articles, Issue Forums, Alliance Forums, Region ForumsPrions scare the the hell out of me in ways I could never have imagined...
http://en.wikipedia.org/wiki/PrionThey are protein mutations that are not identified as intrusive by the immune system. For an indefinite amount of time, the brain can produce totally correct proteins. But one prion causes a chain reaction that leads to destruction of part or all of the brain.
Mad cow disease is a bovine example of a prion disease. Fatal familial insomnia is a human example where the thalamus is utterly destroyed by prions over the course of several months. In that time, those afflicted lose the ability to sleep. They eventually go through phases of psychosis and coma that always lead to death.
Prion diseases can be inherited. They can also be transmitted through direct contact with prion infected tissue.
I don't know how I would react if I found out I suffered from a prion disease.
MADem
(135,425 posts)HYANNIS Five Cape Cod Hospital patients have been told they are at low risk of having been exposed to a rare, fatal brain disease that may have been transferred to them from a surgical instrument.
The case of Creutzfeldt-Jakob disease was first identified by the New Hampshire Department of Health and Human Services after the instrument was used on a patient who had brain surgery there in May, according to a statement from Cape Cod Hospital.
That patient died in August, and doctors believe he had the deadly degenerative brain disease.
Health officials warn that the proteins that cause the disease may have been present on the instrument, which is shared among a number of hospitals....The instrument went through at least four sterilization procedures before arriving at Cape Cod Hospital from New Hampshire, said Georgia Dash, director of infection prevention for Cape Cod Healthcare. It is very difficult to get rid of every trace of the prions (infectious proteins) that can cause Creutzfeldt-Jakob disease during sterilization, but Cape Cod Hospital performed an extra cleaning procedure upon acquiring the instrument, Dash said. This "double process" makes it very unlikely anyone was exposed, she added.
"Sterilization" does nothing to prions. They are not alive. Any cleaning process has to be able to physically break the proteins apart by either chemical or thermal methods. We're talking a lot of heat, or very strong chemicals.
MADem
(135,425 posts)How much heat would be needed? Boil 'em for an hour? Irradiate?
I wonder what kinds of chemicals would do it?
It is scary--I think if I were a patient I'd want to buy my own equipment, new, if I could afford it!!!
mn9driver
(4,426 posts)Cats Cradle. Ice-nine was a form of ice that water liked better than regular ice, so any water that touched it immediately became ice-nine. Not good for living things; it's a very creepy yet allegorical story, like a lot of his work.
I don't know exactly how much heat it would take to break one of these things up.
MADem
(135,425 posts)I love DU, I learn something new every day!!!
pinboy3niner
(53,339 posts)Mnemosyne
(21,363 posts)Gothmog
(145,321 posts)The memorial is this weekend and I hope to learn more from my family
mainer
(12,022 posts)MADem
(135,425 posts)Who knew that hospitals shared stuff like that? I guess the manufacturer "rents 'em out" instead of selling them...?
mainer
(12,022 posts)I've seen reports of other neurosurgical tools that have spread prions around. Scary indeed.
Tikki
(14,557 posts)Both scare the hell out of me...
Tikki
Whisp
(24,096 posts)again.
hair on my arms is standing up, I kid you not.
ackkkkk!
mainer
(12,022 posts)And squirrel brains.
Chickens and pigs, however, seem not to get prion diseases.
Crepuscular
(1,057 posts)to support your claim that humans can contract a prion-based disease from eating Elk meat. The Cervid version of transmissible spongiform encephalopathy is chronic wasting disease and there is no credible evidence that humans can contract CWD or a CJD varient, from consuming the meat from CWD positive deer and elk.