Welcome to DU! The truly grassroots left-of-center political community where regular people, not algorithms, drive the discussions and set the standards. Join the community: Create a free account Support DU (and get rid of ads!): Become a Star Member Latest Breaking News General Discussion The DU Lounge All Forums Issue Forums Culture Forums Alliance Forums Region Forums Support Forums Help & Search

Gravitycollapse

(8,155 posts)
Fri Sep 6, 2013, 03:42 AM Sep 2013

Prions scare the the hell out of me in ways I could never have imagined...

http://en.wikipedia.org/wiki/Prion




They are protein mutations that are not identified as intrusive by the immune system. For an indefinite amount of time, the brain can produce totally correct proteins. But one prion causes a chain reaction that leads to destruction of part or all of the brain.

Mad cow disease is a bovine example of a prion disease. Fatal familial insomnia is a human example where the thalamus is utterly destroyed by prions over the course of several months. In that time, those afflicted lose the ability to sleep. They eventually go through phases of psychosis and coma that always lead to death.

Prion diseases can be inherited. They can also be transmitted through direct contact with prion infected tissue.

I don't know how I would react if I found out I suffered from a prion disease.
15 replies = new reply since forum marked as read
Highlight: NoneDon't highlight anything 5 newestHighlight 5 most recent replies
Prions scare the the hell out of me in ways I could never have imagined... (Original Post) Gravitycollapse Sep 2013 OP
This is rather terrifying.... MADem Sep 2013 #1
Ice-nine. mn9driver Sep 2013 #6
What is "ice-nine," and how does that work? MADem Sep 2013 #7
It's a reference to a Kurt Vonnegut novel: mn9driver Sep 2013 #10
Ahhhh!!! MADem Sep 2013 #11
Has anyone seen MFM lately? pinboy3niner Sep 2013 #2
K&R nt Mnemosyne Sep 2013 #3
One of my Aunts just died from CJD Gothmog Sep 2013 #4
Surgical instruments not cleaned of prions with normal autoclaving. mainer Sep 2013 #5
I believe these are the same instruments that were sent to Cape Cod Hospital... MADem Sep 2013 #8
And it's not the first time this has happened. mainer Sep 2013 #13
OK, I'll be the first to say I thought you misspelled 'prisons'.. Tikki Sep 2013 #9
o jesus I haven't thought of that in a long time and now I'm scared too. Whisp Sep 2013 #12
A relative of mad cow disease. Can also get it from eating elk meat. mainer Sep 2013 #14
No evidence Crepuscular Sep 2013 #15

MADem

(135,425 posts)
1. This is rather terrifying....
Fri Sep 6, 2013, 06:42 AM
Sep 2013
http://www.capecodonline.com/apps/pbcs.dll/article?AID=/20130906/NEWS/309060341

HYANNIS — Five Cape Cod Hospital patients have been told they are at low risk of having been exposed to a rare, fatal brain disease that may have been transferred to them from a surgical instrument.

The case of Creutzfeldt-Jakob disease was first identified by the New Hampshire Department of Health and Human Services after the instrument was used on a patient who had brain surgery there in May, according to a statement from Cape Cod Hospital.

That patient died in August, and doctors believe he had the deadly degenerative brain disease.

Health officials warn that the proteins that cause the disease may have been present on the instrument, which is shared among a number of hospitals....The instrument went through at least four sterilization procedures before arriving at Cape Cod Hospital from New Hampshire, said Georgia Dash, director of infection prevention for Cape Cod Healthcare. It is very difficult to get rid of every trace of the prions (infectious proteins) that can cause Creutzfeldt-Jakob disease during sterilization, but Cape Cod Hospital performed an extra cleaning procedure upon acquiring the instrument, Dash said. This "double process" makes it very unlikely anyone was exposed, she added.

mn9driver

(4,426 posts)
6. Ice-nine.
Fri Sep 6, 2013, 09:15 AM
Sep 2013

"Sterilization" does nothing to prions. They are not alive. Any cleaning process has to be able to physically break the proteins apart by either chemical or thermal methods. We're talking a lot of heat, or very strong chemicals.

MADem

(135,425 posts)
7. What is "ice-nine," and how does that work?
Fri Sep 6, 2013, 11:36 AM
Sep 2013

How much heat would be needed? Boil 'em for an hour? Irradiate?

I wonder what kinds of chemicals would do it?

It is scary--I think if I were a patient I'd want to buy my own equipment, new, if I could afford it!!!

mn9driver

(4,426 posts)
10. It's a reference to a Kurt Vonnegut novel:
Fri Sep 6, 2013, 12:04 PM
Sep 2013

Cats Cradle. Ice-nine was a form of ice that water liked better than regular ice, so any water that touched it immediately became ice-nine. Not good for living things; it's a very creepy yet allegorical story, like a lot of his work.

I don't know exactly how much heat it would take to break one of these things up.

MADem

(135,425 posts)
8. I believe these are the same instruments that were sent to Cape Cod Hospital...
Fri Sep 6, 2013, 11:38 AM
Sep 2013

Who knew that hospitals shared stuff like that? I guess the manufacturer "rents 'em out" instead of selling them...?

mainer

(12,022 posts)
13. And it's not the first time this has happened.
Fri Sep 6, 2013, 12:15 PM
Sep 2013

I've seen reports of other neurosurgical tools that have spread prions around. Scary indeed.

 

Whisp

(24,096 posts)
12. o jesus I haven't thought of that in a long time and now I'm scared too.
Fri Sep 6, 2013, 12:15 PM
Sep 2013

again.

hair on my arms is standing up, I kid you not.

ackkkkk!

mainer

(12,022 posts)
14. A relative of mad cow disease. Can also get it from eating elk meat.
Fri Sep 6, 2013, 12:17 PM
Sep 2013

And squirrel brains.

Chickens and pigs, however, seem not to get prion diseases.

Crepuscular

(1,057 posts)
15. No evidence
Fri Sep 6, 2013, 12:55 PM
Sep 2013

to support your claim that humans can contract a prion-based disease from eating Elk meat. The Cervid version of transmissible spongiform encephalopathy is chronic wasting disease and there is no credible evidence that humans can contract CWD or a CJD varient, from consuming the meat from CWD positive deer and elk.

Latest Discussions»General Discussion»Prions scare the the hell...