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no financial incentive to develop ebola vaccine...the fact that people are dying isn't enough (Original Post) spanone Oct 2014 OP
Not strange - sick PumpkinAle Oct 2014 #1
You nuts? Warpy Oct 2014 #2
not my words...watch the video. spanone Oct 2014 #4
And, another example of the benefits of capitalism. Tierra_y_Libertad Oct 2014 #3
More. proverbialwisdom Oct 2014 #5
that's despicable. but even if it weren't skipped due to greed, drugs like that take a long time to dionysus Oct 2014 #6
It's bad that money has anything to do with it, but money alone does not create a vaccine Bluenorthwest Oct 2014 #7
There are a bunch of them. Hepatitis C is a good example. MineralMan Oct 2014 #9
Hep C is a very good answer, MM. HIV also. About 35 million people have died from HIV related causes Bluenorthwest Oct 2014 #11
And we have one Ebola death in the US and a few thousand in West Africa. MineralMan Oct 2014 #13
I can understand the urge for some to use fear as a sort of talisman when they feel lacking in Bluenorthwest Oct 2014 #14
The Reagan years were a wasteland of indifference. MineralMan Oct 2014 #15
Ebola vaccine research has been going on for years. MineralMan Oct 2014 #8
As always, MM, you take the time to develop an informed opinion . . . Journeyman Oct 2014 #21
Cure?!? No ongoing ca$h from that but if enough folks with enough money get it TheKentuckian Oct 2014 #10
A vaccine is preventative, it is not a cure. Bluenorthwest Oct 2014 #12
Some years ago congress had a bill regarding "orphan drugs" to address this. Does anyone know jwirr Oct 2014 #16
The NIH was working one one. ColesCountyDem Oct 2014 #17
It's quite likely we could have had one years ago, if there had been $ in it. Warren DeMontague Oct 2014 #18
Pharmeceutical companies are in business to make money, not to make people healthier. hedgehog Oct 2014 #19
This is nonsense Yo_Mama Oct 2014 #20
Apropos of this... Princess Turandot Oct 2014 #25
The article in Bloomberg was mentioning the government really is the only customer davidpdx Oct 2014 #22
The saying is that the second pill cost 15 cents to make. The first cost $2 billion (nt) Recursion Oct 2014 #24
Malaria kills 3x as many Africans, HIV-AIDS an order of magnitude more Recursion Oct 2014 #23
We need to pitch the idea to them in bomb form. Jamastiene Oct 2014 #26
Ginning up fear Turbineguy Oct 2014 #27
That's normally where governments step in. Kablooie Oct 2014 #28
So why doesn't the US government offer a huge prize (say half a billion dollars) Nye Bevan Oct 2014 #29
The government needs to fund it. nt Logical Oct 2014 #30
Update. proverbialwisdom Oct 2014 #31

PumpkinAle

(1,210 posts)
1. Not strange - sick
Sun Oct 19, 2014, 02:44 PM
Oct 2014

because this disease is so predominantly in Africa, there will be nothing done by big pharma - disgusting, true and immoral.

Warpy

(111,359 posts)
2. You nuts?
Sun Oct 19, 2014, 02:44 PM
Oct 2014

This disease is so scary that every suburbanite with zero chance of exposure is going to line up for the jab just because there are a handful of cases in the country.

They'll be hard pressed to make enough to get to a few people in West Africa.

proverbialwisdom

(4,959 posts)
5. More.
Sun Oct 19, 2014, 03:07 PM
Oct 2014
MEET THE PRESS
Author Laurie Garrett says the development pipeline for producing a Ebola vaccine was slowed by lack of financial incentive.
Published October 19th 2014, 9:46 am


http://www.cfr.org/experts/global-health-hiv-aids-bioterrorism/laurie-garrett/b1781



Laurie Garrett
Senior Fellow for Global Health


Expertise
Global health systems; chronic and infectious diseases; bioterrorism; public health and its effects on foreign policy and national security...

Bio
Since 2004, Laurie Garrett has been a senior fellow for global health at the Council on Foreign Relations (CFR) in New York. Ms. Garrett is the only writer ever to have been awarded all three of the Big "Ps" of journalism: the Peabody, the Polk, and the Pulitzer. Her expertise includes global health systems, chronic and infectious diseases, and bioterrorism.

Ms. Garrett is the best-selling author of The Coming Plague: Newly Emerging Diseases in a World Out of Balance (Farrar, Straus, and Giroux, 1994) and Betrayal of Trust: The Collapse of Global Public Health (Hyperion Press, 2000). Over the years, she has also contributed chapters to numerous books, including AIDS in the World (Oxford University Press, 1993), edited by Jonathan Mann, Daniel Tarantola, and Thomas Netter, and Disease in Evolution: Global Changes and Emergence of Infectious Diseases (New York Academy of Sciences, 1994), edited by Mary E. Wilson. Her latest book is I Heard the Sirens Scream: How Americans Responded to the 9/11 and Anthrax Attacks.

She graduated with honors in biology from the University of California, Santa Cruz. She attended graduate school in the Department of Bacteriology and Immunology at University of California, Berkeley, and did laboratory research at Stanford University with Dr. Leonard Herzenberg. During her PhD studies, she started reporting on science news at KPFA, a local radio station. The hobby soon became far more interesting than graduate school, and she took a leave of absence to explore journalism. At KPFA, Ms. Garrett worked on a documentary, coproduced with Adi Gevins, that won the 1977 George Foster Peabody Award.

<>

heney headed CFR for two 2-year terms (see Wikipedia). Is CFR regarded as objective or agenda driven?

dionysus

(26,467 posts)
6. that's despicable. but even if it weren't skipped due to greed, drugs like that take a long time to
Sun Oct 19, 2014, 03:09 PM
Oct 2014

create, and a long time to test and approve.

 

Bluenorthwest

(45,319 posts)
7. It's bad that money has anything to do with it, but money alone does not create a vaccine
Sun Oct 19, 2014, 03:29 PM
Oct 2014

Can you think of any virus feared for years by rich Westerners that still has no vaccine? I sure can.

MineralMan

(146,333 posts)
9. There are a bunch of them. Hepatitis C is a good example.
Sun Oct 19, 2014, 03:56 PM
Oct 2014

It kills more people each year in the U.S. than Ebola ever will. There's a treatment now, but it's unaffordable for most people who have Hep C. And then there's HIV? No vaccine for that yet, either. How many has HIV killed now? Ebola is a minor risk in the United States. It will continue to be such.

 

Bluenorthwest

(45,319 posts)
11. Hep C is a very good answer, MM. HIV also. About 35 million people have died from HIV related causes
Sun Oct 19, 2014, 04:14 PM
Oct 2014

And forget the US, HIV is the number one cause of death in Africa, more than 70% of the people living with HIV are in Africa and 2011 shows 1.2 million HIV deaths in Africa, 12,000 in North America.

MineralMan

(146,333 posts)
13. And we have one Ebola death in the US and a few thousand in West Africa.
Sun Oct 19, 2014, 04:24 PM
Oct 2014

It's good to have some scale here. Vaccines are difficult to create, difficult to test, and difficult to produce in quantities that would be sufficient. Since we haven't succeeded with Hep C and HIV, what makes people think an Ebola vaccine is some sort of easy job?

Personally, I find it upsetting when people make assumptions about why there is no vaccine for certain diseases. While they blame a lack of money as the reason, they appear to be forgetting that anyone who comes up with a viable HIV vaccine or one for Hepatitis C will find a marketplace that is eager to buy those. That seems obvious. And yet, no vaccine that works is available, despite major efforts to develop vaccines for both of those viruses.

Ebola, too. People have been trying to find a working vaccine for Ebola for a long time. Frankly the team that develops a vaccine for any of the three viruses I mentioned will end up with a Nobel Prize in medicine and the company that makes any of those vaccines will make a pantload of money.

No research? That's nonsense. The research continues and has continued for quite a long time on all of those and many other deadly or epidemic viral diseases.

Some use incorrect information to blame one reason or another for the failure to develop these life-saving vaccines. If those people would actually go and look to see how many people are working on such vaccines, they wouldn't speak so quickly.

 

Bluenorthwest

(45,319 posts)
14. I can understand the urge for some to use fear as a sort of talisman when they feel lacking in
Sun Oct 19, 2014, 04:38 PM
Oct 2014

knowledge. Fear and denial were very popular in the days when many were dying of HIV/AIDS and our science knew almost nothing and our government utterly ignored it. But at that time we had actual lack of knowledge, thousands of deaths and actual government apathy and inaction. By comparison, the US reaction to ebola has been pretty great, even in Africa, where, by comparison, we did nothing with HIV for many extra years because Reagan did nothing at home.

MineralMan

(146,333 posts)
8. Ebola vaccine research has been going on for years.
Sun Oct 19, 2014, 03:38 PM
Oct 2014

See this link:
http://www.niaid.nih.gov/topics/ebolamarburg/research/pages/default.aspx

Also, Google Ebola Vaccine Research for information on actual research that is going on.

A Canadian effort is about to ship an experimental vaccine right now. Link:
http://www.bbc.com/news/health-29680393

See, the thing is that if you rely on advocacy websites for information, you may not get actual facts, but advocacy.

Go do the Google search, and then look at actual information rather than opinion. People have been working on a vaccine for Ebola, along with the Marburg virus and one for Lassa fever. You can find actual information if you actually search for it. Or you can find claims by advocacy websites that say no research is happening. It's up to you to decide whether you want biased opinion or fact.

Me? I prefer factual information.

Journeyman

(15,041 posts)
21. As always, MM, you take the time to develop an informed opinion . . .
Mon Oct 20, 2014, 12:57 AM
Oct 2014

I wish there were more like you on this site. Far too many are content to find any wild opinion and run with it, rather than take the time to check it out.

Thanks for the effort you put into providing useful information.

TheKentuckian

(25,029 posts)
10. Cure?!? No ongoing ca$h from that but if enough folks with enough money get it
Sun Oct 19, 2014, 04:09 PM
Oct 2014

we may see advances toward treatments.

 

Bluenorthwest

(45,319 posts)
12. A vaccine is preventative, it is not a cure.
Sun Oct 19, 2014, 04:20 PM
Oct 2014

A vaccine, the world is your customer stock and a constantly refreshing stock at that. A vaccine never stops selling.

jwirr

(39,215 posts)
16. Some years ago congress had a bill regarding "orphan drugs" to address this. Does anyone know
Sun Oct 19, 2014, 05:04 PM
Oct 2014

what happened to that bill?

ColesCountyDem

(6,943 posts)
17. The NIH was working one one.
Sun Oct 19, 2014, 05:16 PM
Oct 2014

Until the Teabaggers and other GOP-ers cut their funding, that is. Had they not done so, it would likely be in production by now.

hedgehog

(36,286 posts)
19. Pharmeceutical companies are in business to make money, not to make people healthier.
Sun Oct 19, 2014, 05:43 PM
Oct 2014

That's just the nature of the Capitalist system. The situation won't change unless and until we develop alternate methods. For example, what if the Veteran's Administration and/or Medicare contracted to have some of the vital generics made whenever they're n short supply?

Yo_Mama

(8,303 posts)
20. This is nonsense
Sun Oct 19, 2014, 06:02 PM
Oct 2014

There have been pre-attempts, but the reality is that no vaccine could be tested, because there were so few human cases. So the research was just taken to a certain level and then kind of held.

You really can only prepare and test vaccines for illnesses that have a certain residual level of human infections. When "large" outbreaks occur years and perhaps a decade apart, and consist of under 500 cases, there's no way to even test a vaccine. When they occur sporadically, from different viruses, and in different geographic settings, there's no way to predict an outbreak to test efficacy. Any attempt to do so would be unethical.

How could any regulatory agency approve a vaccine without proof that it works? What would be the point? Vaccines have to be given to a large group of people to work, and all vaccines carry some risk of adverse effects to their recipients. You are not going to inoculate millions of people for a disease that might kill 200 people in five years, because you'd create more harm to humans than possible benefit. Instead public health measures against Ebola have concentrated on an effective early response to outbreaks.

Obviously now that has changed. There are already experimental vaccines. From WHO:
http://www.who.int/mediacentre/news/ebola/01-october-2014/en/

They'll probably be first tested on HCW, who can knowledgeably assent and are at high risk if working in the affected areas.

Until you had something like we have now, you could never have a commercial vaccine.

Princess Turandot

(4,787 posts)
25. Apropos of this...
Mon Oct 20, 2014, 05:23 AM
Oct 2014

back in July, Sierra Leone's Dr. Sheik Humarr Khan, who was one of the most dedicated experts on hemorrhagic illnesses in Africa, was felled by ebola. At the time, one of the companies working on the Zmapp treatment drug contacted his physicians at Medecins Sans Frontieres (Doctors Without Borders) and offered them some of the very small quantity of the drug that they had hand. (Zmapp is the treatment drug that was eventually given to Dr. Brantly, among a handful of other patients in different countries. Some of the patients who received it lived and some died anyway.)

After extensive discussion, MSF decided not to accept the drug, which had shown promise on monkeys in an early 2014 study. Why? Because it could not have been given to a human up until that point, and they were concerned that it might make things worse.

Science doesn't happen in sound bites.

davidpdx

(22,000 posts)
22. The article in Bloomberg was mentioning the government really is the only customer
Mon Oct 20, 2014, 01:45 AM
Oct 2014

in these types of situations and that the research and funding depended upon funding and approval from within the government. The problem is that the first dose of vaccine is the most expensive because that comes from all the time and energy spent getting it approved. If there is no need for it, then it would sit on a shelf with maybe a limited supply (vaccines I do believe can expire if they are too old).

I agree a vaccine would have probably helped, but I think ebola has been contained enough (outside of Africa) that it is not a problem. We now need to focus on Africa where it is still a problem.

Recursion

(56,582 posts)
23. Malaria kills 3x as many Africans, HIV-AIDS an order of magnitude more
Mon Oct 20, 2014, 02:05 AM
Oct 2014

TB kills twice as many.

The takeaway here isn't that "greedy corporations are sitting on a vaccine" but that "there are finite resources that can be devoted to much more serious problems".

And, anyways, an ebola vaccine would make a ton of money. But a cheap, portable malaria prophylaxis and/or treatment would save a lot more lives.

Jamastiene

(38,187 posts)
26. We need to pitch the idea to them in bomb form.
Mon Oct 20, 2014, 05:52 AM
Oct 2014

Tell the MIC that they can bomb parts of Africa if they make sure to include an Ebola vaccine, then give them free reign to bomb anywhere, as long as it includes an Ebola vaccine. They'll be itching do it then.

No, that wouldn't work. They can already bomb whoever the hell they want without the international community doing anything about it and without any requirements. Just think, the cost of one bomb could probably fund research enough to make a vaccine really quick. There is always enough money for bombs. Health care? Safety and wellbeing of citizens? Nope. They have been siphoning money from the helpful stuff for more bombs than we can ever drop and to line the pockets of the companies attached to the MIC for ages now.

Kablooie

(18,641 posts)
28. That's normally where governments step in.
Mon Oct 20, 2014, 06:38 AM
Oct 2014

they take on needed projects that aren't economically profitable.
Damn Republicans can't seem to grasp this fact.

Nye Bevan

(25,406 posts)
29. So why doesn't the US government offer a huge prize (say half a billion dollars)
Mon Oct 20, 2014, 07:04 AM
Oct 2014

to the first drug company to come up with a working vaccine?

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