Within minutes of Hillary Clinton’s announcement Sunday that she will seek the 2016 Democratic nomination for U.S. president, her already-declared Republican rivals pounced. Sens. Ted Cruz of Texas and Rand Paul of Kentucky tweeted their attacks on Clinton to their hundreds of thousands of followers. Reaction also poured in from the Democratic and GOP political establishment, which had anticipated Clinton’s announcement for days before her top aide broke the news Sunday afternoon.

“We’re ready for Hillary,” Cruz said in a video tweeted on his official Twitter account. “We know exactly what to expect. Hillary Clinton represents the failed policies of the past. Does America want a third Obama term? Or are we ready for strong conservative leadership to make America great again?”

Cruz, who officially launched his White House bid nearly three week ago, also asked for campaign donations. Paul tweeted an animated image that plays up the former secretary of state’s email scandal. The words “Liberty, not Hillary” are revealed at the end of the animation. To the same effect, Paul also released a video attack ad that includes snippets from his official launch last week.

Other likely Republican and Democratic contenders quickly released statements on Clinton’s announcement. In an email to his supporters, Jeb Bush wrote it ”isn’t going to be easy” to defeat Clinton. Bush, who has yet to officially declare his candidacy, asked for donations to the Right to Rise PAC. “This is going to be a long fight, but together, we will stop her,” Bush wrote. “Thank you for your help, you’ll be hearing from me again soon.” Sen. Marco Rubio of Florida did not release a statement Sunday, but was expected to announce his candidacy Monday.