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Related: Editorials & Other Articles, Issue Forums, Alliance Forums, Region ForumsItalian doctor may have found surprisingly simple cure for Multiple Sclerosis
more. faster. please.
this could help millions of people
An Italian doctor has been getting dramatic results with a new type of treatment for Multiple Sclerosis, or MS, which affects up to 2.5 million people worldwide. In an initial study, Dr. Paolo Zamboni took 65 patients with relapsing-remitting MS, performed a simple operation to unblock restricted bloodflow out of the brain and two years after the surgery, 73% of the patients had no symptoms. Dr. Zambonis thinking could turn the current understanding of MS on its head, and offer many sufferers a complete cure.
Multiple sclerosis, or MS, has long been regarded as a life sentence of debilitating nerve degeneration. More common in females, the disease affects an estimated 2.5 million people around the world, causing physical and mental disabilities that can gradually destroy a patients quality of life.
ts generally accepted that theres no cure for MS, only treatments that mitigate the symptoms but a new way of looking at the disease has opened the door to a simple treatment that is causing radical improvements in a small sample of sufferers.
Italian Dr. Paolo Zamboni has put forward the idea that many types of MS are actually caused by a blockage of the pathways that remove excess iron from the brain and by simply clearing out a couple of major veins to reopen the blood flow, the root cause of the disease can be eliminated.
Dr. Zambonis revelations came as part of a very personal mission to cure his wife as she began a downward spiral after diagnosis. Reading everything he could on the subject, Dr. Zamboni found a number of century-old sources citing excess iron as a possible cause of MS. It happened to dovetail with some research he had been doing previously on how a buildup of iron can damage blood vessels in the legs could it be that a buildup of iron was somehow damaging blood vessels in the brain?
He immediately took to the ultrasound machine to see if the idea had any merit and made a staggering discovery. More than 90% of people with MS have some sort of malformation or blockage in the veins that drain blood from the brain. Including, as it turned out, his wife.
He formed a hypothesis on how this could lead to MS: iron builds up in the brain, blocking and damaging these crucial blood vessels. As the vessels rupture, they allow both the iron itself, and immune cells from the bloodstream, to cross the blood-brain barrier into the cerebro-spinal fluid. Once the immune cells have direct access to the immune system, they begin to attack the myelin sheathing of the cerebral nerves Multiple Sclerosis develops.
He named the problem Chronic Cerebro-Spinal Venous Insufficiency, or CCSVI.
Zamboni immediately scheduled his wife for a simple operation to unblock the veins a catheter was threaded up through blood vessels in the groin area, all the way up to the effected area, and then a small balloon was inflated to clear out the blockage. Its a standard and relatively risk-free operation and the results were immediate. In the three years since the surgery, Dr. Zambonis wife has not had an attack.
http://thesecrets.info/italian-doctor-may-have-found-surprisingly-simple-cure-for-multiple-sclerosis-2/
merrily
(45,251 posts)rhett o rick
(55,981 posts)SoLeftIAmRight
(4,883 posts)please please please - is right - this time
merrily
(45,251 posts)Fairgo
(1,571 posts)would that it be true!
Warpy
(111,339 posts)because improving cerebral blood flow wouldn't explain or affect the damage to the myelin sheath in peripheral nerves. It would still be good if it improved the lesions within the brain. I just doubt it will cure the whole disease.
merrily
(45,251 posts)KT2000
(20,587 posts)hemochromotosis - build-up of iron in the blood. This could account for the high incidence of MS in Scotland. It would be interesting to figure out the genetic background of most MS sufferers.
The cure for Celtic Disease is giving blood.
eniwetok
(1,629 posts)Viva_La_Revolution
(28,791 posts)While ms patients do have excess iron in certain parts of the brain, you cannot just drain it out! Either the cells die from accumulated iron, or the dying cells leave iron behind, they don't know yet. No reports of this in any journals, and my mom suffered 30 years from ms, so i keep up with the research. I wish it were true
CountAllVotes
(20,878 posts)Sadly. Another scam just like the rest of the "treatments" out there I am very sorry to have to write as I, yes I, know this crap disease only too well.
Omaha Steve
(99,714 posts)No way to stop it from getting there.
LiberalLoner
(9,762 posts)CountAllVotes
(20,878 posts)Nice to see you again.
Lonely journey isn't it?
LiberalLoner
(9,762 posts)greiner3
(5,214 posts)Be unethical and maybe against the law
CTyankee
(63,912 posts)so bad for him. He lives alone and we've told him he needs to get a LifeAlert device to summon help if he falls and can't get up. We worry about him...
Viva_La_Revolution
(28,791 posts)Response to Viva_La_Revolution (Reply #6)
Duppers This message was self-deleted by its author.
Joe Chi Minh
(15,229 posts)he obtained that data, if not by empirical trials.
Viva_La_Revolution
(28,791 posts)This was announced 6 years ago, and has not been duplicated
Viva_La_Revolution
(28,791 posts)Joe Chi Minh
(15,229 posts)jtuck004
(15,882 posts)CountAllVotes
(20,878 posts)Have noticed that the doctors RX'ing the various drugs really cater to the patients taking them. Money does talk!
Those that are not taking these drugs receive poor care at best.
A woman I know is getting those infusions and she relocated to another state and she needed that monthly infusion (that can cause a fatal brain diease btw). She called up a local neurologist and got right in (cannot get in here or a six month wait) and they hooked her up and infused her and said to her, "You aren't in any pain or anything are you honey?".
She does not have pain as a symptom (lucky her!) and told them no.
If you are not on one of these costly treatments, they simply give you no care or minimal care at best.
My new "doctor" is a nurse as no one would have me being I don't want the infusions or injections. However, I live in chronic pain but hey, that doesn't matter now does it "honey".
What a sickening reality eh?
Joe Chi Minh
(15,229 posts)do have many very committed, altruistic doctors here still, as well as a probably normal quota of the more venal and ambitious worldlings that such a cerebral profession will inevitably attract. Indeed, did so as a large majority, prior to the setting up of the National Health Service, primarily by Labour's Aneurin Bevan.
Look at the marvellous work done by Doctors without Borders. I should imagine there are some British doctors among them. My wife used to trot out what her grandfather used to say about avoiding doctors, but she came to rely on them increasingly, contributing mightily to her living some thirty years loner than she was expected to. There are even good, altruistic lawyers, too, some of whom help to staff the free Citizens' Advice Bureaus we have here in the UK. We benefited from their generosity on a couple of occasions.
In the US, I believe, there was a time, not so long ago, when there was a massive number of completely unwarranted surgical operations performed, simply to enhance the incomes of the doctors.
Response to Viva_La_Revolution (Reply #4)
cyberpj This message was self-deleted by its author.
eniwetok
(1,629 posts)mr blur
(7,753 posts)Still, it makes a change from the usual Woo-inspired fake cures people try to sell us.
30 years here and in that time so many breakthroughs that did not materialize. I hope after testing this may be one.that works.
ismnotwasm
(42,011 posts)I read about this a few years ago. It's nonsense. My husband had MS for over 20 years, and we've seen far more than our share of snake oil cures.
Codeine
(25,586 posts)CountAllVotes
(20,878 posts)People become so desperate w/this illness they'll do anything to overcome it. However, no such luck seems to be the sad reality IMO.
It sickens me the way drug companies and parasites like this guy prey on the sick. M.S. patients are real money makers for the medical industry and frauds pushing bogus "treatments", special diets, etc.
Joe Chi Minh
(15,229 posts)CountAllVotes
(20,878 posts)What is CCSVI?
Some studies have indicated that a phenomenon called CCSVI (chronic cerebrospinal venous insufficiency), a reported abnormality in blood drainage from the brain and spinal cord, may contribute to nervous system damage in MS. This hypothesis was put forth by Dr. Paolo Zamboni from the University of Ferrara in Italy in 2009, and is now being pursued by other investigators as well.
Based on the results of initial preliminary findings, Dr. Zamboni and others state that this pilot study warrants a subsequent larger and better controlled study to definitively evaluate the possible impact of CCSVI on the disease process in MS. There have been additional studies published, some of which showing results that conflict with the original findings. This amplifies the need for larger, well-controlled studies that can quickly provide answers regarding next steps.
National MS Society research leaders first met with Dr. Zamboni in February 2010 at New York Universitys Society-funded MS Center of Excellence and again in April when the Society hosted, along with the American Academy of Neurology, a live Web forum on CCSVI. Based on the results of preliminary research which has been published in respected peer journals, Dr. Zamboni and others have recommended larger scale studies to determine if CCSVI may be treated through an endovascular surgical procedure, which involves inserting a tiny balloon or stent into blocked veins in order to improve the flow of blood out of the brain and spinal cord.
Dr. Zamboni suggests that if further evidence supports the link between MS and CCSVI, that its treatment may ultimately add to the arsenal of therapies available for MS. He emphasized the need for more research on his hypothesis, and noted that people with MS should remain on their immunomodulatory therapies as has his wife after her endovascular surgical procedure.
http://www.nationalmssociety.org/Research/Research-News-Progress/Research-News/CCSVI/About-CCSVI
*****
As for the rest of it, I refuse to grease the palms of big pharma like Novartis who just got busted the other day for their lies.
They can rot in hell with their torturous treatments and infusions.
As far as Zamboni goes, knew of one person who had this done and felt better for one day was the result. Big deal.
Downwinder
(12,869 posts)Blow right through the donut hole.
Response to Downwinder (Reply #24)
cyberpj This message was self-deleted by its author.
Response to cyberpj (Reply #36)
cyberpj This message was self-deleted by its author.
Downwinder
(12,869 posts)I had been on Patient Assistance until then. Think the price was $1,250/mo. That's when it got screwy. Must be the high cost of Chinese Hamster ovaries.
Downwinder
(12,869 posts)The whole system is so muddled you don't know what is happening.
I know they have an active Patient Assistance Program.
I have gone through four Part "D" providers. Every year it seems something changes and I have little or no say in the matter.I just ride along making sure I have a stock on hand. I go on catastrophic coverage in March and then worry about what the next January will bring.
ProfessorGAC
(65,168 posts)Total cost is $1600 per month. My share is $70.
BCBS pays the other $1530.
I've been on it for nearly 20 years and at no time was the retail cost anywhere close to $6k. Who's reporting that, downwinder?
Downwinder
(12,869 posts)My share is $7.50 and PANF picks that up.
ProfessorGAC
(65,168 posts)I'm on Betaseron, so now i see that we're on two very different meds. That might be the whole reason, because those are two different interferons. So, the patent may be up on one and not on the other.
Downwinder
(12,869 posts)Rebif was introduced they switched me over. Did not notice any difference. Skipped the ramp up. Just went from 48hrs. to 60 hrs.
CountAllVotes
(20,878 posts)Heard the price of one of the other ones, Copaxone, has doubled and then some this past year. Infusions of Tysabri (yet another one) costs $10K a month.
How do you make a go of it?
Best of luck is about all I can say.
Downwinder
(12,869 posts)With our system, sometimes it is better to be indigent.
I was forced onto Social Security early retirement which turned out to be a blessing though I complained at the time. If I made $500 more a year I would not qualify for the Extra help.
When someone asks how are we going to pay for free tuition,n I ask them why they are paying $72,000 a year to keep me around. There is no cost benefit for it. Tuition for two or more, on the other hand makes sense.
CountAllVotes
(20,878 posts)You are right about that. A person I know with M.S. is on Medicare, Medicaid, etc. etc. etc.
That's what happens if you get sick after working for 25 years, you don't qualify for jack unless you are there already IMO.
Downwinder
(12,869 posts)you will end up indigent.
blm
(113,091 posts)Would hate for this to be untrue since so many families are suffering.
CountAllVotes
(20,878 posts)She's in a better place is what I'm always told.
I think there is a better place and yep, she is there.
She is no longer suffering so all is good eh?
again.
dorkzilla
(5,141 posts)I got to the article because I was trying to justify a plan to wander around Tuscany because the weather is better.
http://www.nytimes.com/2012/10/28/magazine/a-controversial-cure-for-multiple-sclerosis.html?_r=0
ETA Have to read more - he's been doing this surgery since 2009 and has had limited success with small groups. I know he started researching MS when his wife was diagnosed.
PS - MS SUCKS THE BIG ONE so good on him for even trying.
djean111
(14,255 posts)dorkzilla
(5,141 posts)I have MS so I'm thankful to anyone who would attempt to help. It's doubtful to my mind that Dr Zamboni would try and scam patients who are experiencing what his own wife has endured. I could be wrong, but it seems that the man is in earnest.
djean111
(14,255 posts)And I sorry you are going through this. Hopefully someday something will prove effective.
dorkzilla
(5,141 posts)Tomorrow I go back to see them...I had MRIs in the past week that show bigger and new lesions in my brains so I may be eligible for some of their trials.
You might find this interesting:
http://www.ny1.com/nyc/all-boroughs/health-and-medicine/2016/03/23/trial-study-looks-at-stem-cells--ability-to-reverse-ms-damage.html
djean111
(14,255 posts)regenerating retinas from stem cells. I was thinking that's cool, because one of my retinas started to detach about 20 years ago, and it was tacked back into place with lasers, just in time. Plus I will soon need cataract surgery, and have wondered whether that is also open to this kind of science.
Thanks again for the link!
Response to dorkzilla (Reply #32)
cyberpj This message was self-deleted by its author.
dorkzilla
(5,141 posts)I'm 50 so I am not surprised since only 3% of MS patients are diagnosed after 40 and it progresses quickly. Hopefully I'll get in!
Response to dorkzilla (Reply #38)
cyberpj This message was self-deleted by its author.
dorkzilla
(5,141 posts)And I agree about the stem cell research. They're also doing stem cell clinicals in England and Israel, plus they're doing studies on the relationship between gut bacteria and MS in Ireland. It all seems promising!
Will check in tomorrow on the health board if they're considering me for any of their trials (they have a few going with Weill Cornell).
ETA-thank you for the prayers!
brush
(53,869 posts)Is there a Nobel Prize for something like this?
uriel1972
(4,261 posts)but I don't think it will be a Novel Prize...
Jitter65
(3,089 posts)Chelation removes heavy and trace minerals from the blood.
Downwinder
(12,869 posts)He took a blood sample and after a while he showed me a picture of the parasites. I came home and found the exact same picture on the web. Never went back.
SheilaT
(23,156 posts)Meaning the body has mysteriously started to attack some organ or system. That's a long, long way from blood vessel blockages, or too much iron in the blood.
The skeptic in me wants to see this replicated.
Response to SheilaT (Reply #26)
cyberpj This message was self-deleted by its author.
SheilaT
(23,156 posts)so I tend to pay attention to all of them.
MS is far, far worse than mere baldness. But I expect the people who fall for quack cures is the same everywhere.
Hope you are doing as well as you can be.
allan01
(1,950 posts)littlewolf
(3,813 posts)and if I posted garbage I am so sorry ..
I read some of the replies. I did not mean
to do any harm
it sounded like
so hopeful. if I harmed anyone by
posting this. I am so very sorry.
djean111
(14,255 posts)are finding out new things in other areas. it's all good, and always good to hope, IMO, unless one turns down something that actually works. So, thank you!
Response to littlewolf (Reply #31)
cyberpj This message was self-deleted by its author.
progressoid
(49,999 posts)eniwetok
(1,629 posts)It was an interesting theory... and I believe this 2006 paper was his first http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1633548/
Maybe there's some truth that excess free iron creates a storm of free radicals that destroys myelin.
Two of my friends have MS. One was diagnosed with progressive MS about 10 years ago and had the procedure done 3-4 years ago and while he felt better for a short time, the MS has only increased in severity since then. But if liberation surgery helps some people... then that's great. MS is an insidious disease.
jonks2746
(41 posts)Hope more progress is made very soon.
greymouse
(872 posts)Excess iron is easily removed by filtering blood. And easily detected by a blood test.
I hate it when some off the wall very preliminary result is trumpeted as a wonder advance, raising hopes falsely.
LiberalArkie
(15,728 posts)diseases that are related to iron buildup.