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babylonsister

(171,074 posts)
Sat Aug 6, 2016, 08:25 AM Aug 2016

Florida cleared to release genetically modified mosquitoes in Zika fight

Florida cleared to release genetically modified mosquitoes in Zika fight

US Food and Drug Administration finds ‘no significant’ environmental impact of experimental release of insects after 15 Zika infections were reported in Miami

Jessica Glenza
Friday 5 August 2016 15.35 EDT
Last modified on Friday 5 August 2016 17.25 EDT


A release of mosquitoes genetically engineered to produce dead offspring and thus combat the spread of the Zika virus has been approved in Florida by the US Food and Drug Administration (FDA).
Florida mobilizes to control mosquitos causing 'unprecedented' Zika outbreak

On Thursday, Florida officials said the same species of mosquito had transmitted 15 Zika infections in the Wynwood neighborhood of Miami, the first cases to be caused by mosquitoes in the mainland US.

Hadyn Parry, chief executive of Oxitec, the company that created the genetically altered insects, said he was “really pleased” by the FDA approval of the experimental release, and called on authorities to grant Oxitec emergency authorization to release the insects in Miami as a control measure.

“We’re really pleased today,” said Parry. “Aedes aegypti is public enemy No 1. It is exclusively a human vector, it lives in and around the home, if you go into the center of town that’s where it is.”

Oxitec, a spinoff from a project at Oxford University, was recently purchased by Intrexon, the corporation that produces non-browning “Arctic” apples and fast-fattening “AquaBounty” salmon. The FDA announcement nearly clears the way for it to release the mosquitoes in an experimental trial on Key Haven, a small island in the Florida Keys. One obstacle remains, however: the voters of Monroe County.

In November, roughly 52,000 voters will decide if they want the trial to go forward. The referendum will not be legally binding, but most members of the elected Florida Keys mosquito control board have said they will abide by voters’ wishes. The trial has been hotly contested, with many residents vocally opposed to the mosquitoes’ release.

more...

https://www.theguardian.com/world/2016/aug/05/florida-genetically-modified-mosquitoes-zika?CMP=fb_us#link_time=1470432099

14 replies = new reply since forum marked as read
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Florida cleared to release genetically modified mosquitoes in Zika fight (Original Post) babylonsister Aug 2016 OP
Aedes aegypti is an invasive species. longship Aug 2016 #1
As a Floridian, no one is against this. FLPanhandle Aug 2016 #2
Dry Season in Florida HockeyMom Aug 2016 #4
The release now will lower the population until the dry season takes care of them. Warpy Aug 2016 #13
They are not being released now HockeyMom Aug 2016 #14
That's somewhat simplified jberryhill Aug 2016 #3
Yes, you are essentially correct. longship Aug 2016 #8
Wouldn't this affect just one generation? Il_Coniglietto Aug 2016 #5
How long before someone starts a rumor that these genetically modified mosquitoes... Buckeye_Democrat Aug 2016 #6
Congratulations! RapSoDee Aug 2016 #9
You mean like this: Baitball Blogger Aug 2016 #11
Noooooo!! Buckeye_Democrat Aug 2016 #12
Good news. Vattel Aug 2016 #7
The genetically engineered mosquitoes will be easy to identify. lpbk2713 Aug 2016 #10

longship

(40,416 posts)
1. Aedes aegypti is an invasive species.
Sat Aug 6, 2016, 08:36 AM
Aug 2016

And these genetically modified males will only mate with aedes aegypti females since mosquitos do not interbreed. There is no danger with this release since males don't bite -- they only mate -- and the genetic modification gives them a very short life anyway, which after all is the whole point.

When they mate with females, her offspring share the genetic modification, and they die before they mature. Problem solved.

Note: aedes aegypti also spreads dengue!

So who would be against this?

FLPanhandle

(7,107 posts)
2. As a Floridian, no one is against this.
Sat Aug 6, 2016, 08:40 AM
Aug 2016

Unless they don't understand science and have watched too many Hollywood movies.

 

HockeyMom

(14,337 posts)
4. Dry Season in Florida
Sat Aug 6, 2016, 09:10 AM
Aug 2016

beginning in about November (vote taken) when it may not rain for weeks, even months. Won't be very much standing water around for mosquitoes to breed in. They cannot breed in moving bodies of water like the Ocean or Gulf. Science. Droughts are issued. Don't water your lawns, etc. Will these sterile male mosquitoes find enough local lady friends to mate with? The local mosquito population will go down in the Dry Season.

It gets very dry here in South Florida by January/February. I cannot speak to the Panhandle area, but I would think that the Keys weather is very similar to the mainland south.

Warpy

(111,277 posts)
13. The release now will lower the population until the dry season takes care of them.
Sat Aug 6, 2016, 11:18 AM
Aug 2016

The lifespan of the adult female mosquito is six to eight weeks. Once she mates, she bites. If most of the males she encounters are the GMO males, the offspring will die before they mature enough to mate, causing a relative collapse in the population that will persist into the next wet season. That's the theory, anyway. It will decrease the immediate population and that will decrease the probability of a large Zika outbreak.

There have been 15 symptomatic cases around Miami. Zika can be a subtle disease, some 80% of people exhibiting no symptoms to a few aches and pains they pass off as overexertion. Kids who get it will be immune for life. The problem is with pregnant women, Zika is diabolical enough to be an STD as well as mosquito borne.

The good news is that all four vaccine types in the works are safe and effective in early trials. A dengue vaccine is now being tested widely in Mexico and results should be out in the next year or so.

 

HockeyMom

(14,337 posts)
14. They are not being released now
Sat Aug 6, 2016, 01:16 PM
Aug 2016

FDA is waiting until November so the local residents can vote on the issue. It says so in the article. Non binding vote, but at least the residents deserve a chance to have their say in the matter. By November the fear of being bitten by a mosquito in the majority of the country will be over. Weather alone will take care of mosquitoes.

Of those 15 people identified, 12 were men and 3 were women. 6 had no symptoms at all, but were identified by door to door urine samples in the neighborhood. Possibly could be more than that when you consider that people move around, visit other areas, etc. No way to know who was in that area on any given date. How many people come and go in a big city like Miami?

 

jberryhill

(62,444 posts)
3. That's somewhat simplified
Sat Aug 6, 2016, 09:08 AM
Aug 2016

The released mosquitos are not "all" males. They are mostly males. At the scale needed, it is not possible to separate them by sex with 100% accuracy.

Hence, there is a statistical risk that a released adult female will transmit the virus from an infected individual to an uninfected individual. The point is that there is expected to be a net decrease over time of the mosquitos.

This is not a panacea, as Oxitec mosquitoes had been released in Brazil to combat dengue prior to the Brazilian Zika outbreak.

longship

(40,416 posts)
8. Yes, you are essentially correct.
Sat Aug 6, 2016, 09:41 AM
Aug 2016

But any mosquito with the trait dies quickly. So any messiness has a null effect. The idea is that the offspring die before they reach adulthood, which they do.

And the tests in Brazil (and one presumes other places) show results consistent with smaller aedes aegypti populations, therefore less Zika and dengue spread.

In other words, it works, which is all that is being claimed here.

Thank you for your clarification.

Il_Coniglietto

(373 posts)
5. Wouldn't this affect just one generation?
Sat Aug 6, 2016, 09:24 AM
Aug 2016

At least per release? If offspring are designed not to survive through sexual maturity.

Buckeye_Democrat

(14,855 posts)
6. How long before someone starts a rumor that these genetically modified mosquitoes...
Sat Aug 6, 2016, 09:28 AM
Aug 2016

... contain a "zombie virus" or some such nonsense?

lpbk2713

(42,760 posts)
10. The genetically engineered mosquitoes will be easy to identify.
Sat Aug 6, 2016, 10:00 AM
Aug 2016



They will be the ones with the flip-up sunglasses and they can be observed driving funny.


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