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TheBlackAdder

(28,209 posts)
Tue Aug 16, 2016, 03:55 PM Aug 2016

New Pharma Bros Strike: This time it's the EpiPen. . . Up 450%, from $50 to $600 for a 2-pack.

Last edited Tue Aug 16, 2016, 04:37 PM - Edit history (1)

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I wondered why my copay started at nothing and then slowly climbed to $90 last year. Here's the culprit:


https://thinkprogress.org/life-saving-allergy-treatment-is-becoming-too-expensive-for-families-to-afford-4fe5dd9aab39#.aszdm6jbx


But Mylan has priced this life-saving medication, which can keep airways open during severe allergic reactions, far out of reach for many families. Over the past nine years, since Mylan bought the rights to the EpiPen, the price for the easy-to-use injectors has quintupled — increasing about 450 percent, from around $50 for one injector to $600 for a pack of two.

The only way the device can be purchased is in packs of two — a move made after an FDA recommendation that allergy sufferers carry two doses just in case. Selling EpiPens in packs of two, however, means that if one is lost or used, to replace it, people must buy an extra (essentially doubling their cost) they may not need. The actual dose of the hormone epinephrine (also known as adrenaline) delivered by the device costs approximately $1.
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For Mylan, the strategy appears to be paying off. The medication is a cash-cow for the company: According to Bloomberg Business, EpiPens provide about 40 percent of Mylan’s operating profits, accounting for billions of dollars.



More at the link.


(Please K&R for exposure. Thanks)


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53 replies = new reply since forum marked as read
Highlight: NoneDon't highlight anything 5 newestHighlight 5 most recent replies
New Pharma Bros Strike: This time it's the EpiPen. . . Up 450%, from $50 to $600 for a 2-pack. (Original Post) TheBlackAdder Aug 2016 OP
Have to wonder -- madamesilverspurs Aug 2016 #1
who dat? SheriffBob Aug 2016 #21
Google "punchable" and you'll find out. Orrex Aug 2016 #43
Hello SEC? FBI? Where are you? Initech Aug 2016 #2
What should the SEC and FBI do? Travis_0004 Aug 2016 #36
Isn't the FBI the one who busted Shkreli? Initech Aug 2016 #38
For an unrelated crime dsc Aug 2016 #44
I have to pay the full $600.00 Elwood P Dowd Aug 2016 #3
Can you go for syringes? sharp_stick Aug 2016 #9
I will talk to the Doc about it when this one starts approaching exp. date. Elwood P Dowd Aug 2016 #13
Unfortunately, it's a difficult proposition for someone in the middle of an attack dhol82 Aug 2016 #35
My doctor says if kept out of hot places, such as cool cabinet and not in a car, it lasts longer. TheBlackAdder Aug 2016 #10
OMG . My son has a peanut allergy and annabanana Aug 2016 #4
Well that's it...I'm going to sell my sons. ileus Aug 2016 #5
More profiteering off the vulnerable Calculating Aug 2016 #6
And Trump supporters see nothing wrong with that. Dark n Stormy Knight Aug 2016 #18
I wish the FTC still had some teeth Warpy Aug 2016 #7
It's the antitrust laws. They're being ignored. Why? elehhhhna Aug 2016 #30
Repukes defund the antitrust division of the DOJ meow2u3 Aug 2016 #33
Generics was my first thought too, but from the article: Ruby the Liberal Aug 2016 #31
Oohh, good information, thank you Warpy Aug 2016 #34
I second that warning Ruby the Liberal Aug 2016 #37
As someone who works for a pharma sharp_stick Aug 2016 #8
Token offer. Meanwhile, this costs ALL taxpayers across the country, especially with EMT services. TheBlackAdder Aug 2016 #16
Like in that Travolta Tarantino film? Ooh ouch. elehhhhna Aug 2016 #29
seeing stuff like this makes you kinda think maybe we should nationalize it dembotoz Aug 2016 #11
It's a no brainer Calculating Aug 2016 #12
That's right they should charge for medical products and services, just like Jesus did. Volaris Aug 2016 #45
Just imagine the bill that he would have hit Lazarus with. n/t whopis01 Aug 2016 #48
I just refilled mine, not sure if this was before the hike in price but redstatebluegirl Aug 2016 #14
Yep, you have no choice but to buy a 2-pack. Elwood P Dowd Aug 2016 #15
Same here - Pharmacist said they can't split them Ruby the Liberal Aug 2016 #26
Let's see, should I (a) buy groceries, (b) pay the rent or (c) buy medication to save my child... Still In Wisconsin Aug 2016 #17
That's disgusting and inhuman. nt SusanCalvin Aug 2016 #19
They have got to open the Med Market up to worldwide Producers,,, Cryptoad Aug 2016 #20
disgusting SheriffBob Aug 2016 #22
I worked with children in after school program HockeyMom Aug 2016 #23
Sons of bitches! Now it makes sense Ruby the Liberal Aug 2016 #24
"Pay up... NOW." Wednesdays Aug 2016 #25
this should be criminal. spanone Aug 2016 #27
Yep. nt SusanCalvin Aug 2016 #39
148.00 for 2 with a legit prescription online from Canada. elehhhhna Aug 2016 #28
Even that sounds like lesser highway robbery. SusanCalvin Aug 2016 #40
About a year and half ago, there was no Tolinase available REP Aug 2016 #32
Metformin is actually dirt cheap Ms. Toad Aug 2016 #42
I'm Stage III and insulin is far safer REP Aug 2016 #47
As to kidney disease - it depends on the stage and disease duration. Ms. Toad Aug 2016 #49
Maintaining normal HbA1c isn't enough REP Aug 2016 #53
It's unconscionable, but try this: Ms. Toad Aug 2016 #41
Thanks, but please see my reply to #16. TheBlackAdder Aug 2016 #46
nose/face - most people prefer to have their nose intact if there is an option to save it Ms. Toad Aug 2016 #50
I've used the coupon in the past, when they first offered it. TheBlackAdder Aug 2016 #51
Inhuman bloodsucking bloodsuckers stage left Aug 2016 #52

Elwood P Dowd

(11,443 posts)
3. I have to pay the full $600.00
Tue Aug 16, 2016, 04:09 PM
Aug 2016

since I just have regular Medicare w/o any other supplemental or drug plan. Also, the box says the expiration date is May 2017. It's tough trying to survive on Social Security and just the regular Medicare plan with no extra policies.

sharp_stick

(14,400 posts)
9. Can you go for syringes?
Tue Aug 16, 2016, 04:16 PM
Aug 2016

I know a couple of people on Medicare that have switched to syringe and vial to save costs.

Elwood P Dowd

(11,443 posts)
13. I will talk to the Doc about it when this one starts approaching exp. date.
Tue Aug 16, 2016, 04:41 PM
Aug 2016

So far, I haven't had to use one, but it's scary not to have one just in case.

dhol82

(9,353 posts)
35. Unfortunately, it's a difficult proposition for someone in the middle of an attack
Tue Aug 16, 2016, 08:03 PM
Aug 2016

to go find the vials and syringe, alcohol the top of the vial, pull up the proper dosage and then inject. It's hard enough for a doctor who doesn't do it often to be adept at this. One can do it, but it ain't easy.
That's the reason epi-pens are so valuable.
The price increase is unconscionable.

TheBlackAdder

(28,209 posts)
10. My doctor says if kept out of hot places, such as cool cabinet and not in a car, it lasts longer.
Tue Aug 16, 2016, 04:22 PM
Aug 2016

.


He said with proper storage it could last two or more years.


But, like with anything on the web... ask your own personal doctor for their advice.


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annabanana

(52,791 posts)
4. OMG . My son has a peanut allergy and
Tue Aug 16, 2016, 04:10 PM
Aug 2016

has to keep one handy. There are SO MANY people dependent on these things in a life or death emergency.

Calculating

(2,955 posts)
6. More profiteering off the vulnerable
Tue Aug 16, 2016, 04:14 PM
Aug 2016

These companies know they can get away with it because they sell a specialized product that most people don't need. The small segment of the population in need of these epi-pens aren't influential enough to bring about change.

The people responsible for this are simply despicable and have no conscience. They simply see human lives as a means to enrich their bank accounts. They'll happily squeeze people for all they're worth.

Dark n Stormy Knight

(9,771 posts)
18. And Trump supporters see nothing wrong with that.
Tue Aug 16, 2016, 06:24 PM
Aug 2016

Which shows how very much is wrong with them. Fatcats, Like Trump, making money at any cost is just fine with them. (Unless of course it affects them directly, then they whine, sue, bear arms, etc.)

Warpy

(111,277 posts)
7. I wish the FTC still had some teeth
Tue Aug 16, 2016, 04:15 PM
Aug 2016

and would take on extortionate drug pricing. They're toothless, just like all the other government agencies that have been systematically underfunded, positions left vacant, and laws gutted.

Have your doc write for a generic. There are other brands out there that might not have ridiculous pricing.

 

elehhhhna

(32,076 posts)
30. It's the antitrust laws. They're being ignored. Why?
Tue Aug 16, 2016, 07:26 PM
Aug 2016

In the 80's we had some damned good antitrust prosecution going on. Where's the AG for fucks sake?

meow2u3

(24,764 posts)
33. Repukes defund the antitrust division of the DOJ
Tue Aug 16, 2016, 07:34 PM
Aug 2016

This way, there's not enough resources to go after the profiteers and monopolists.

Ruby the Liberal

(26,219 posts)
31. Generics was my first thought too, but from the article:
Tue Aug 16, 2016, 07:26 PM
Aug 2016
Like Kleenex or Q-tips, the brand has become nearly eponymous with the object. EpiPen prescriptions account for the vast majority of prescriptions for epinephrine— 85 percent in the first quarter of 2015, a number that has likely increased as Mylan’s dominance of the market has increased. There is virtually no alternative: EpiPen’s one major competitor, Auvi-Q, was pulled from the market in October 2015 due to a malfunction that sometimes delivered a suboptimal dose of medication, and the FDA rejected a bid from Teva Pharmaceuticals to produce a generic version.


Lovely, right? I wonder how that 85% market share looks now, now that their competition is out.

Warpy

(111,277 posts)
34. Oohh, good information, thank you
Tue Aug 16, 2016, 07:54 PM
Aug 2016

That was their closest competitor.

I honestly don't suggest getting multidose vials of epinephrine and syringes because in a panic situation, when you are having trouble breathing, it's just going to be too difficult to draw up accurately to inject.

Ruby the Liberal

(26,219 posts)
37. I second that warning
Tue Aug 16, 2016, 08:24 PM
Aug 2016

Anaphylaxis is terrifying and the panic can be really frightening. Especially if its quick reaction like from a bee sting. Having a vial of epinephrine lying around for self-dosing in an emergency is a really really bad idea.

sharp_stick

(14,400 posts)
8. As someone who works for a pharma
Tue Aug 16, 2016, 04:15 PM
Aug 2016

company this disgusts the hell out of me.

I can also say, after talking with a lot of other scientists in my company and in the industry as a whole it disgusts damn near all of them too.

Most of these companies aren't "pharma" as we use the term in that they don't actually make medicine, at least not new medicine. They can't use the "R&D is expensive" line because they don't have R&D. Generics used to be all about saving money and producing in quantity but they figured out that if not enough companies are making a product they have a captive audience. Scumbags plain and simple. It's not enough to make money, they have to always make more money.

This is marketing and business departments run amok. I know it's been brought up at a couple of our company wide meetings and the bosses at least know that we don't want to be in the same field as these dirtbags.

Now, that being said, you might be able to help yourself if you use the savings card. I haven't looked into this one specifically but I use one for a different medicine and it's reduced my copay to zero.

https://www.epipen.com/copay-offer/

TheBlackAdder

(28,209 posts)
16. Token offer. Meanwhile, this costs ALL taxpayers across the country, especially with EMT services.
Tue Aug 16, 2016, 05:09 PM
Aug 2016

.


Nonetheless, some states increasingly alarmed by the high cost of supplying EpiPens to emergency medical response teams — including Colorado, Maryland, and South Carolina — are pushing to train EMTs to administer syringes of epinephrine instead of EpiPens. Replacing the auto-injectors with syringes could potentially save taxpayers thousands; a county in Seattle where first-responders use generic kits of epinephrine instead of branded EpiPens reported savings of more than $150,000 in one year.



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Calculating

(2,955 posts)
12. It's a no brainer
Tue Aug 16, 2016, 04:28 PM
Aug 2016

But you'd have to convince the Jesus following right wingers who are stubbornly sticking to their "if you can't afford medicine you should just die" ideology.

Volaris

(10,272 posts)
45. That's right they should charge for medical products and services, just like Jesus did.
Wed Aug 17, 2016, 09:28 AM
Aug 2016

Oh, wait...

redstatebluegirl

(12,265 posts)
14. I just refilled mine, not sure if this was before the hike in price but
Tue Aug 16, 2016, 04:48 PM
Aug 2016

my out of pocket went from 30 to 100 dollars and I had to buy two.

Ruby the Liberal

(26,219 posts)
26. Same here - Pharmacist said they can't split them
Tue Aug 16, 2016, 07:13 PM
Aug 2016

They wanted $395 from me (last I recall it was like $25 for 1 of them). I told them to cancel it. Good thing I live close to an ER.

 

Still In Wisconsin

(4,450 posts)
17. Let's see, should I (a) buy groceries, (b) pay the rent or (c) buy medication to save my child...
Tue Aug 16, 2016, 06:02 PM
Aug 2016

not a decision I'm personally having to make but many, many are.

 

HockeyMom

(14,337 posts)
23. I worked with children in after school program
Tue Aug 16, 2016, 06:56 PM
Aug 2016

who needed those EpiPens. No School Nurse on Duty after school hours. Nobody there. Yes, we had some Emergency Medical Training but if those kids didn't have those EpiPens because of cost? All we would be able to do was call 911 to help them. How long would that take as opposed to having those EpiPens right there on school premises for an emergency? Call 911 AFTER their use.

Ruby the Liberal

(26,219 posts)
24. Sons of bitches! Now it makes sense
Tue Aug 16, 2016, 07:10 PM
Aug 2016

I had an epipen here that expired about a year back, so asked my Doc for a new prescription last month. WITH my insurance, it was $395.

I told them to cancel it, and when the insurance company called to ask me why I cancelled the prescription, I told them I'd haul it to the ER if I got stung by a bee or ate anything that causes me anaphalaxis.

SusanCalvin

(6,592 posts)
40. Even that sounds like lesser highway robbery.
Tue Aug 16, 2016, 11:10 PM
Aug 2016

Let the exorbitant profits be made on luxuries.

I've no objection to soaking the rich - let's Hoover the $$$ *down*!

REP

(21,691 posts)
32. About a year and half ago, there was no Tolinase available
Tue Aug 16, 2016, 07:27 PM
Aug 2016

Tolinase is an old, inexpensive oral diabetes drug, perfect for people like me, who have steroid-induced diabetes with non-diabetic kidney disease. Metformin, a newer and more expensive drug, is very harmful to the kidneys and I can't take it.

So what happened when the one oral medicine I could take was unavailable? Well, first I could started on another oral agent that gave me pancreatitis. What was left? Insulin.

The cheapest, low-tech insulin is about $120/vial. The one that is right for me, Lantus, is over $200/vial.

Actually this ended up being to my advantage; the Tolinase was causing very mild pancreatitis as well, and I feel much better on insulin ... and though the shortage ended up being a good thing for me, I wonder how many people are paying for insulin when Tolinase is still a good choice for them.

Ms. Toad

(34,076 posts)
42. Metformin is actually dirt cheap
Tue Aug 16, 2016, 11:30 PM
Aug 2016

(a typical dose - 1000 grams/day) ranges from $0 to $10 for 30 days. (In contrst, Tolinase is still available - and costs $85 - $130 at the reasonably priced pharmacies.) [Prices from GoodRX.com, and the Metformin price is in the range I pay - the total cost of my prescription is never as high as my copay.]

Metformin not significanty harmful to healthy kidneys - and recent studies suggest that it may even be safe for people with kidney disease. You might want to check with your doctor, again.

REP

(21,691 posts)
47. I'm Stage III and insulin is far safer
Wed Aug 17, 2016, 12:30 PM
Aug 2016

I get 12 vials of Lantus for $40. Tolinase is now available - it wasn't for awhile - and 100 days cost $20. It's worth the extra $20 per 100 days not to feel like shit I have very good insurance, though; not everyone does.

By definition, diabetics don't have healthy kidneys though. Nearly 100% of all diabetics show signs of diabetic nephropathy, either on UA or biopsy.

Ms. Toad

(34,076 posts)
49. As to kidney disease - it depends on the stage and disease duration.
Wed Aug 17, 2016, 02:22 PM
Aug 2016

Yes, kidney disease is common - and far more people with diabetes have undiagnosed kidney disease than are aware of it, acording to recent studies. But it is not universal (or "by definition&quot - particularly among individuals who are able to maintain normal blood glucose levels.

I am very protective of my kidneys - and have substituted fat for protein to provide the calories I'm not getting via carbohydrates because processing fat is easier on kidneys than processing excess protein. That said, multiple tests over the past few months, have confirmed that I have kidney disease. (I also have cancer; since many of the diagnostic tests are dangerous if you have impaired kidney funciton - so the state of my kidneys is well documented.)

You're absolutely right about insulin v. sunfonylurea - I'd make exactly the same choice. I wouldn't take tolinase (or any other sulfonylurea) if you paid me to. If it get to that stage, I will switch immediately to insulin - which will permit the pancreas to continue with its normal function as long as it is able. There is ample research that sulfonylureas accelerate the death (or long term damage) to the beta cells that produce insulin (not to mention the life-threatening side effect of pancreatitis).

(My biggest reaction was to the suggestion that metformin was more expensive - since both my spouse and mother got metformin for years for free - and it is still available for free from at least one vendor. I've never paid more than $10 for a 90 day supply (below my copay, so I'm paying the full cost of the drug).

REP

(21,691 posts)
53. Maintaining normal HbA1c isn't enough
Wed Aug 17, 2016, 05:40 PM
Aug 2016

While anecdote isn't the plural of data, I'm an example. Before being overdosed on steroids, my HbA1c was 4.6; at diagnosis (two weeks after a previous HbA1c, too) 9.3; since diagnosis; 6 (highest 7.1).

I have secondary diabetic nephropathy as well as neuropathy. The good news is my retinas seem okay, knock wood!

If I hadn't undergone a kidney biopsy around the time I became diabetic (for what turned out to be primary idiopathic focal segmental glomerulosclerosis - say that five times fast!), the diabetic nephropathy probably wouldn't have been discovered until years later, when my nephrotic syndrome became less pronounced and albumen was able to be detected in my urine (previously, I was excreting 10+ g/protein so not only did I not have a protein restriction, I had to add protein).

At the time I was OD'd into diabetes, I got transferred to the care of one of the leading diabetes specialists in my region, and my nephrologist's reputation is even better. I'm pretty sure that I'm doing as well as I am with a disease with as dismal a prognosis as FSGS is because of their aggressive management

Best wishes as you treat your cancer. I did that in my 20s, and was very surprised when 5 precancerous polyps were removed from my colon last year - I was in for something completely different. There are few things more frustrating and terrifying.

Ms. Toad

(34,076 posts)
41. It's unconscionable, but try this:
Tue Aug 16, 2016, 11:23 PM
Aug 2016
https://www.epipen.com/copay-offer/

I got into a big fight with the pharmacist, who refused to substitute a generic (pharma nonsense keeps a bio-available equivalent from being treated as a generic because of the delivery mechanism), before I found the coupon for my daughter.

Turns out her allergist had given her one, but she didn't understand what it was. . . . gee, I wonder where her allergist got the coupon from, and why he insisted that she carry epipens for her desensitization therapy in the first place (since she's never - even at the testing phase - come close to needing it). (My personal opinion is that any allergist engaging in desensitisation therapy should keep a supply on hand for administration during the mandatory 20 minute waiting period, rather than demanding that each of his patients carry one (now 2) with them at a throw-away cost of $600 per pair every year or so. If they're used - charge them to the patient, just like they do everything else they keep on hand and charge as used.)

Ms. Toad

(34,076 posts)
50. nose/face - most people prefer to have their nose intact if there is an option to save it
Wed Aug 17, 2016, 02:27 PM
Aug 2016

rather than sacrificing it to punish your face.

I was offering a practical personal solution for anyone personally burned by what I clearly labeled an unconscionable (systemic) practice.

I made no suggestion that it was a systemic solution.

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