DT takes Propecia, a hair loss drug linked with confusion, other cognitive effects.

http://www.huffingtonpost.com/entry/trump-propecia-haiir-loss_us_58936376e4b06f344e4058a6

In a snicker-worthy disclosure by President Donald Trump’s longtime personal physician, readers of The New York Times learned Thursday that the leader of the free world takes a small daily dose of the drug finasteride ― otherwise known as Propecia ― which is used to treat male-pattern baldness.

The revelation by Dr. Harold N. Bornstein that the president uses a prostate-related drug to grow scalp hair was not previously known publicly, according to the Times story, and appears to explain why Trump has a very low level of prostate specific antigen, or PSA, a marker sometimes used to diagnose prostate cancer. The newspaper said it had four telephone conversations with Bornstein, whose office is in Manhattan, about Trump’s overall health.

SNIP

“The FDA-approved pill has been called into question, with emerging research and a slew of lawsuits suggesting that finasteride may be more dangerous than previously believed,” reported Men’s Journal. “Users report that its side effects — inability to orgasm, painful erections, chronic depression, insomnia, brain fog, and suicidal thoughts — can last long after patients stop taking the pill.”

Since 2011, at least 1,245 lawsuits have been filed against Propecia’s manufacturer, Merck, alleging that the company didn’t sufficiently warn users of sexual and cognitive side effects. Patients and physicians reportedly call the effects “Post-Finasteride Syndrome” because, they say, symptoms often persist after discontinuing the drug. The National Institutes of Health has added PFS to its rare-diseases database. Merck told Men’s Journal the the company “stands behind the demonstrated safety and efficacy profile of Propecia.”

SNIP


http://abcnews.go.com/Health/baldness-drug-propecia-long-lasting-possibly-permanent-sexual/story?id=16758123

Abdulmaged Traish, a professor of biochemistry and urology at Boston University School of Medicine, said scientists are just beginning to investigate finasteride's effects on the brain and nervous system.

"We are just beginning to venture in that direction. It might be in the next five to 10 years that we may find there's more to this story than we know now," Traish said.

He said he would not advise men to take this drug to treat a cosmetic problem like hair loss.




https://www.ncbi.nlm.nih.gov/pubmed/24928450

Persistent sexual, emotional, and cognitive impairment post-finasteride: a survey of men reporting symptoms.
Ganzer CA1, Jacobs AR2, Iqbal F2.
Author information


Abstract
Finasteride is a synthetic 5-? reductase inhibitor, which prevents the conversion of testosterone to dihydrotestosterone and has been used for more than 20 years in the treatment of male pattern hair loss. Randomized, controlled trials have associated finasteride with both reversible and persistent adverse effects. In this pilot study, we sought to characterize sexual and nonsexual adverse effects that men reported experiencing at least 3 months after stopping the medication. Based on previous research on persistent side effects of finasteride, we constructed an Internet survey targeting six domains: physical symptoms, sexual libido, ejaculatory disorders, disorders of the penis and testes, cognitive symptoms, and psychological symptoms and was e-mailed to patients who reported experiencing symptoms of side effects of finasteride. Responses from 131 generally healthy men (mean age, 24 years) who had taken finasteride for male pattern hair loss was included in the analysis. The most notable finding was that adverse effects persisted in each of the domains, indicating the possible presence of a "post-finasteride syndrome."

https://www.nytimes.com/2017/02/01/us/politics/trump-prostate-drug-hair-harold-bornstein.html

About a month ago, Dr. Bornstein said he told Mr. Trump’s secretary, Rhona Graff, “You know, I should be the White House physician.” Past presidents like Ronald Reagan and George H. W. Bush brought their own doctors to the White House, but others have used a White House physician.

Dr. Bornstein was invited to Mr. Trump’s inaugural, although he said it was not as pleasant an experience as he expected. He had to walk a long way to a spot where he thought there would be a chair — he said he has a painful back ailment and nerve damage to a leg — but when he got there, there was no chair.

He stood behind a tree and “never heard anyone speak because I was so uncomfortable from my back and being cold.” He felt, he said, “absolutely miserable.” It seemed to take forever to leave because of the heavy security, he said. The situation was the same at an inaugural ball where there were no tables and chairs. So, he said, unable to chat comfortably with others, he and his wife, Melissa, returned to their hotel early.