Cannabinoids as antioxidants and neuroprotectants

Abstract

Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism. This new found property makes cannabinoids useful in the treatment and prophylaxis of wide variety of oxidation associated diseases, such as ischemic, age-related, inflammatory and autoimmune diseases. The cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease and HIV dementia. Nonpsychoactive cannabinoids, such as cannabidoil, are particularly advantageous to use because they avoid toxicity that is encountered with psychoactive cannabinoids at high doses useful in the method of the present invention. A particular disclosed class of cannabinoids useful as neuroprotective antioxidants is formula (I) wherein the R group is independently selected from the group consisting of H, CH.sub.3, and COCH.sub.3. ##STR1##

http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=6630507.PN.&OS=PN/6630507&RS=PN/6630507

Prohibition is a failed public policy and cannabis and hemp can save the world.

I am sure that further studies will prove many more uses and benefits of drugs derived from marijuana. Even straight off the plant marijuana could replace many high priced medications for a wide variety of conditions and do so with fewer negative side effects and risks. This is indisputable. The facts don't matter. Nor does it matter that most Americans favor decriminalization or legalization. What matters is how much money you can throw at an election to direct the outcome. Pharmaceuticals are flush with cash. Do you think Obama or even the Democratic "leadership" (and I use that term loosely) will risk the wrath of Big Pharma before a major election? No. That isn't going to happen.

in the marketplace.
Take pills for example.
there are those that use them for illness and treatment and some people take them for recreation

most of them medicinal in nature and owned by big pharma and the US Gov.

She's it in spades!

OTC sleeping pills make me groggy the whole next day, and I have heard horror stories about Ambien.

A few months ago I made a tincture with weed, catnip, and chamomile and I have never slept better in my life. I wake up the next morning and feel actually refreshed. I don't go through the day in a burned out haze like I did before.

I am going through the cheerios awfully fast though.

it sounds very calming--and you made me look up cannabis tinctures. I have been making my own cannabis oil for lymphoma, which is in my digestive system (so I think of eating it as treating the cancer topically). It is still helping me keep it under control, and I am very grateful for this plant.

I want to look up which cannabinoids are freed up with alcohol and which ones need oil to be released.Somehow i got it stuck in my head that oil was needed to free up the cancer fighting components, but I am open to new research. Perhaps both methods are beneficial!

Good Dreams XemaSab!

and especially the work of Dr. William Courtney.

I just heard about this concept--and it sounds very promising and interesting!! I have been juicing a lot and making green milkshakes

Ok--I'm off to look up Dr Courtney!!!

on his official website <www.cannabisinternational.org>

Especially informative is the interviews with him and his wife in "The New Settler" newsletter (issue 148).

Also look for a paper he wrote titled "Cannabis as a Unique Functional Food".

and know you have done a good thing today waddirum!!!! I can't believe I haven't heard of this. I hope no one minds if I post this video here:

I was pretty blown away when I first came across this information. And to think of all of the fan leaf that I used to just throw away, because I didn't know better.

What I've gathered from my research is that there are so many more cannabinoids in the plant than just the THC which gets you high. Just as important is the THC-acid (from the raw plant), CBD, CBD-acid (again raw), CBN, CBG, and many others.

Best of luck with your health (and happiness).

Now is not the time to be pushing alternatives to GSK's proven track record of valuable prescription pharmaceuticals. We must rally and support them in this time of need by keeping the devils weed illegal and trusted new chemical compounds that are brought to market in four months that make your toenails fall off the law of the land. You know, for the kids.

I just want to say that--there are some really cool people here.

Hope you are having a great 4th!! and To kpete and everybody!!