Health
Related: About this forumRandomized, double-blind study: CoQ10 cuts all heart related causes of mortality by half.
http://www.sciencedaily.com/releases/2013/05/130525143852.htmThe Q-SYMBIO study (2) randomised 420 patients with severe heart failure (New York Heart Association (NYHA) Class III or IV) to CoQ10 or placebo and followed them for 2 years. The primary endpoint was time to first major adverse cardiovascular event (MACE) which included unplanned hospitalisation due to worsening of heart failure, cardiovascular death, urgent cardiac transplantation and mechanical circulatory support. Participating centres were in Denmark, Sweden, Austria, Slovakia, Poland, Hungary, India, Malaysia and Australia.
CoQ10 halved the risk of MACE, with 29 (14%) patients in the CoQ10 group reaching the primary endpoint compared to 55 (25%) patients in the placebo group (hazard ratio=2; p=0.003). CoQ10 also halved the risk of dying from all causes, which occurred in 18 (9%) patients in the CoQ10 group compared to 36 (17%) patients in the placebo group (hazard ratio=2.1; p=0.01).
CoQ10 treated patients had significantly lower cardiovascular mortality (p=0,02) and lower occurrence of hospitalisations for heart failure (p=0.05). There were fewer adverse events in the CoQ10 group compared to the placebo group (p=0.073).
Professor Mortensen said: "CoQ10 is the first medication to improve survival in chronic heart failure since ACE inhibitors and beta blockers more than a decade ago and should be added to standard heart failure therapy."
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tridim
(45,358 posts)Big Pharma doesn't care.
bemildred
(90,061 posts)Sarah Ibarruri
(21,043 posts)I had a friend on statins and even his doctor told him he needed to take Co-Q-10 because statins diminishes the levels of Co-Q-10 in the body.
Sweet Freedom
(3,995 posts)for both men and women?
dickthegrouch
(3,174 posts)But I've been taking Co-Q10 for years because of chronic dental problems and my Dentist's insistence that Co-Q10 was a necessity. The only question seems to be "How much Co-Q10 should one take?".
FWIW I'm using the Trader Joe's 90mg capsules twice a day as the least expensive solution I can find.
tanyev
(42,559 posts)My husband was put on statins after he was diagnosed with Type I diabetes and soon after noticed that he was accidentally biting his tongue much more often. It was our dentist that told him it was probably caused by the statin and that Co-Q10 would help. It did.
I just want to know why his diabetes doctor never mentioned Co-Q10.
Bill USA
(6,436 posts)you won't find this bias. Consequently, it takes about 20 yrs for an effective natural supplement to be recognized by the medical community, which is steeped in a tradition that laboratory produced pharmaceuticals are the ONLY way to go.
I think the 20 yr period is in order to give the pharmaceutical companies time to come up with a synthetic analogue to the natural substance which they can sell you for 10 to 100 times more. LOL!
flamingdem
(39,313 posts)Very interesting, you have an open minded dentist
dickthegrouch
(3,174 posts)Actually almost any inflammation of the gums will deplete Co-Q10 available to the heart, according to him.
Bill USA
(6,436 posts)inflammation which impacts the whole cardiovascular system. The entree point for the bacteria is the gum line in the mouth. Taking CoQ10 knocks out these bacteria, reducing cardiovascular inflammation, improving heart health. This is also why they tell you flossing is important for heart health - helps hold down the proliferation of the bacteria along the gum line.
Please note, this statement has not been approved by the Pharmaceutical industry.
flamingdem
(39,313 posts)thanks, didn't realize it had to do with the gums.
DeSwiss
(27,137 posts)Bill USA
(6,436 posts)SoapBox
(18,791 posts)Hence why it's so expensive?
Or is that an old-wives tale?
Response to SoapBox (Reply #7)
Th1onein This message was self-deleted by its author.
Bill USA
(6,436 posts)plant. I believe CoQ10 is quite a bit cheaper than it used to be (like 30 yrs ago) because it's being sold in such enormous quantities now.
Response to Bill USA (Original post)
Th1onein This message was self-deleted by its author.
grasswire
(50,130 posts)I take 400 mg/day.
And CoQ10 extended the life of my dear orange tabby cat by two years. He was diagnosed with CHF and hypertrophic cardiomyopathy. Poor prognosis. I started him on CoQ10 along with his Lasix, and he lived a good two more years.
The cardiologist I follow says he can not treat CAD without CoQ10 along with other supplements.