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Related: About this forumBreakthrough could lead to cure for chronic liver disease
http://www.independent.co.uk/news/science/breakthrough-could-lead-to-cure-for-chronic-liver-disease-7536450.htmlMedical scientists have taken an important step towards understanding how the diseased liver can repair itself in a breakthrough that could eventually lead to the development of new treatments for chronic liver illnesses, which at present can only be cured by organ transplants.
The researchers have worked out how to stimulate the production of vital liver cells known as hepatocytes which are lost when the liver is attacked by potentially fatal conditions such as cirrhosis or chronic hepatitis.
Liver disease is the fifth biggest killer in Britain and is the only major cause of death that has seen a continual year-on-year increase over the past 40 years more than twice as many people die of liver disease now compared with 20 years ago.
About 16,000 people in the UK died last year of liver disease, and the number of people on the waiting list for organ transplants has increased from about 300 five years ago to nearly 500 now.
Chemisse
(30,813 posts)are now suffering from serious liver disease (my husband included). This could be really great news if a drug is developed that could stimulate liver renewal.
xchrom
(108,903 posts)what a punim! wanna give smooches!
Chemisse
(30,813 posts)xchrom
(108,903 posts)Th1onein
(8,514 posts)Hepatocytes are lost when the liver is damaged? Hello? Hepatocytes are the main cell of the liver. They ARE the liver. Geez. Of course they are damaged in liver disease!
What they need to do, instead of mucking around with the genes, and potentially causing cancer, is figure out how to stop the damage early, which is a lot easier than administering a drug that has an effect on a specific set of genes and ONLY those genes. (They are playing with fire here.) And, then, simply cut a piece of the liver off. It will regenerate new cells; just like it does for cancer patients who have to have part of it removed.