Welcome to DU! The truly grassroots left-of-center political community where regular people, not algorithms, drive the discussions and set the standards. Join the community: Create a free account Support DU (and get rid of ads!): Become a Star Member Latest Breaking News General Discussion The DU Lounge All Forums Issue Forums Culture Forums Alliance Forums Region Forums Support Forums Help & Search

xchrom

(108,903 posts)
Fri Sep 6, 2013, 09:53 AM Sep 2013

AIDS Turning Point: 'A Cure Is Possible'

http://www.spiegel.de/international/europe/aids-cure-new-science-suggests-breakthrough-ways-of-eradicating-hiv-a-920562.html


Timothy Brown, also known as "The Berlin Patient," listens as he is introduced to speak at a news conference in Washington in 2012. Brown received a bone-marrow stem-cell transplant as treatment for leukemia. The donor was, thanks to genetics, immune to HIV and the immunity seemed to have passed to Brown.

HIV specialist Stefan Fenske's medical clinic, located in Hamburg's university district, isn't a moribund place. The rooms are filled with light, the walls are decorated with modern art and you can hear laughter. Werner (not his real name) is in a good mood as he sits in the consultation room discussing his illness. The 63-year-old refers to the human immunodeficiency virus (HIV) that nestled into his body over 23 years ago as a "subletter," not an enemy or a deadly threat.

Every three months, Thomas travels to Hamburg from the nearby small town where he lives. Blood samples are taken and 15 minutes later he heads home again. "Some healthy people would be happy to have test results like mine," he says. His physician, Dr. Fenske, is also satisfied: "His smoking is definitely a bigger health risk for him than the virus."
Prior to 1996, in the days before highly effective anti-retroviral drugs were developed, Fenske witnessed the horror of AIDS and the deaths of many patients. At the time, the skeletal, emaciated bodies of AIDS patients were sapped of their strength by infections and consumed by tumors.

A New Kind of HIV Patient

The new drugs came too late for Thomas' boyfriend, who died in 1993 of an AIDS-related illness. Thomas was no longer allowed to work as a waiter, and had to go into retirement at the age of 40. "What should I do now?" he asked himself at the time. "Grow old, at any rate!", he vowed.
3 replies = new reply since forum marked as read
Highlight: NoneDon't highlight anything 5 newestHighlight 5 most recent replies
AIDS Turning Point: 'A Cure Is Possible' (Original Post) xchrom Sep 2013 OP
Thanks for the article. R. Daneel Olivaw Sep 2013 #1
We dreaded the words "Male, 20s, pneumonia" from admitting Warpy Sep 2013 #3
Bone marrow transplant is easy to say Warpy Sep 2013 #2
 

R. Daneel Olivaw

(12,606 posts)
1. Thanks for the article.
Fri Sep 6, 2013, 10:22 AM
Sep 2013

My mother remembers seeing some of the first cases where she worked.

Young men with "fevers of unknown origin" were being admitted to the hospital and dying.

Nobody knew what was happening and it was quite distressing seeing "kids" the same age as her children passing away without a definable reason.

As a nurse she had seen death, but this was different.


Let's hope they find a cure and kill this disease for good.

Warpy

(111,277 posts)
3. We dreaded the words "Male, 20s, pneumonia" from admitting
Fri Sep 6, 2013, 04:25 PM
Sep 2013

because most of them would be dead by the end of the shift and there was nothing we could do.

It was a holocaust.

Warpy

(111,277 posts)
2. Bone marrow transplant is easy to say
Fri Sep 6, 2013, 04:22 PM
Sep 2013

but very difficult to do. Many recipients don't live through the massive chemo and radiation it takes to kill off their own bone marrow. Brown was just lucky that his donor had the gene variant that confers immunity to HIV. I've known bone marrow recipients with HIV who later died from the disease because it likes to hide in the central nervous system, only to attack later.

The best hope still lies in a vaccine and new anti viral drugs to fight it in those already infected. While Brown has been cured, the conditions are so rare and extreme that it needs to be called a fluke, not a universal procedure to reverse the disease.

Latest Discussions»Issue Forums»Health»AIDS Turning Point: 'A Cu...