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sl8

(13,898 posts)
Sat Dec 18, 2021, 11:40 PM Dec 2021

Genetic determinants of liking and intake of coffee and other bitter foods and beverages

https://www.nature.com/articles/s41598-021-03153-7

Genetic determinants of liking and intake of coffee and other bitter foods and beverages

Marilyn C. Cornelis & Rob M. van Dam
Scientific Reports volume 11, Article number: 23845
(2021)

[...]

Abstract

Coffee is a widely consumed beverage that is naturally bitter and contains caffeine. Genome-wide association studies (GWAS) of coffee drinking have identified genetic variants involved in caffeine-related pathways but not in taste perception. The taste of coffee can be altered by addition of milk/sweetener, which has not been accounted for in GWAS. Using UK and US cohorts, we test the hypotheses that genetic variants related to taste are more strongly associated with consumption of black coffee than with consumption of coffee with milk or sweetener and that genetic variants related to caffeine pathways are not differentially associated with the type of coffee consumed independent of caffeine content. Contrary to our hypotheses, genetically inferred caffeine sensitivity was more strongly associated with coffee taste preferences than with genetically inferred bitter taste perception. These findings extended to tea and dark chocolate. Taste preferences and physiological caffeine effects intertwine in a way that is difficult to distinguish for individuals which may represent conditioned taste preferences.

[...]

In summary, our genetic analysis suggests the psychostimulant effects of caffeine outweighs the bitterness of caffeine. A greater preference for caffeine based on genetic differences in the physiological effects of caffeine leads to a stronger preference for the taste/smell of coffee and dark chocolate. Similarly, greater sensitivity to the adverse physiological effects of caffeine was associated with avoiding the taste of coffee. Taste preferences and physiological caffeine effects thus seem to become entangled in a way that is difficult to distinguish for individuals. These potential examples of conditioned taste preferences or aversions merit further clinical investigation. This apparent disruption of an innate aversion to bitter taste and its genetic correlation with coffee preferences has important relevance to food and beverage development as well as genetic epidemiological studies of coffee.

[...]



PDF & more at link.
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Genetic determinants of liking and intake of coffee and other bitter foods and beverages (Original Post) sl8 Dec 2021 OP
I dislike coffee. Texaswitchy Dec 2021 #1
How about dark chocolate? sl8 Dec 2021 #2
I do not like dark chocolate. Texaswitchy Dec 2021 #4
Another non-coffee drinker here, and I... 3catwoman3 Dec 2021 #7
Not a wine drinker either. Texaswitchy Dec 2021 #8
Odd, for me I like the smell of coffee though I can only drink it with cream and lots of splenda. cstanleytech Dec 2021 #22
I hate the smell too. OMG, this explains things... The_REAL_Ecumenist Dec 2021 #14
I love coffee I_UndergroundPanther Dec 2021 #3
Pass me the cream and the splenda and I will drink it though not the dark roast as for me cstanleytech Dec 2021 #23
I think the most important takeaway from the article is SCantiGOP Dec 2021 #5
I thought I would grow up to like coffee but never did. Texaswitchy Dec 2021 #6
I never drank coffee until I had to leave the house at 6 to be at work by 7. lark Dec 2021 #24
I love coffee and drink it black, no sugar. Swede Dec 2021 #9
Black coffee & dark chocolate for me RainCaster Dec 2021 #10
👍 Scottie Mom Dec 2021 #11
I roast my own coffee. I have mastered multiple pour over techniques. Coffee is only bitter... cayugafalls Dec 2021 #12
Interesting. PoindexterOglethorpe Dec 2021 #13
Yes, it must have cream and sugar. Manifestor_of_Light Dec 2021 #20
I really like coffee, but I do use a little sweetener (usually a squirt of Stevia), and half PatrickforB Dec 2021 #15
I think I'm an exception to this. I would LIKE the psycho-stimulant effects, if I could get deurbano Dec 2021 #16
I love coffee, the more caffeine, the better, but... GReedDiamond Dec 2021 #17
The older I get the less I sweeten my coffee. Mr.Bill Dec 2021 #18
Primitive coffee-Grind dark beans, put in pitcher. Heat water, dump into grind. Filter after minutes NBachers Dec 2021 #19
I drink coffee, black. murielm99 Dec 2021 #21
I love black coffee. littlemissmartypants Dec 2021 #25

Texaswitchy

(2,962 posts)
4. I do not like dark chocolate.
Sun Dec 19, 2021, 12:01 AM
Dec 2021

I never liked coffee.

Not even the smell.

When I little there was a coffee plant near by and with the right wind you could smell coffee.

I hated that smell.

3catwoman3

(24,051 posts)
7. Another non-coffee drinker here, and I...
Sun Dec 19, 2021, 12:52 AM
Dec 2021

...cannot stand the smell..

Nix on dark chocolate, too.

And, I think dry wines taste like cough syrup.

cstanleytech

(26,319 posts)
22. Odd, for me I like the smell of coffee though I can only drink it with cream and lots of splenda.
Sun Dec 19, 2021, 08:03 AM
Dec 2021

As for dark chocolate and wine I cannot stand either nor can I tolerate the taste of liquor in general.

The_REAL_Ecumenist

(729 posts)
14. I hate the smell too. OMG, this explains things...
Sun Dec 19, 2021, 02:29 AM
Dec 2021

I'm not as weird as I was made to feel. I'm married to a coffee afficionado who has a selection of coffee beans from Asia, Africa, South & Central America. Bruh uses a French Press and grinds beans everyday, 2X a day...Can't complain too much because I introduced him to the French Press.

I_UndergroundPanther

(12,480 posts)
3. I love coffee
Sat Dec 18, 2021, 11:56 PM
Dec 2021

Light roast beans I will drink black.

Dark roast,it tastes like char. Dont like dark roast.
If dark roast coffee is all there is I drink it with a little cream.

With light roast the coffee is a complex flavor. Different beans can have vastly different flavors.

I like beans coffee and cat toe beans,those I just love them they are adorable. When I wake up I get both kinds of beans😸

cstanleytech

(26,319 posts)
23. Pass me the cream and the splenda and I will drink it though not the dark roast as for me
Sun Dec 19, 2021, 08:05 AM
Dec 2021

its way to bitter of a taste.

SCantiGOP

(13,873 posts)
5. I think the most important takeaway from the article is
Sun Dec 19, 2021, 12:06 AM
Dec 2021

that some people like coffee; some don’t.

This could change our entire understanding of the universe.

lark

(23,158 posts)
24. I never drank coffee until I had to leave the house at 6 to be at work by 7.
Sun Dec 19, 2021, 11:15 AM
Dec 2021

Couldn't take the bitterness, but needed to wake up, so added milk and sweetener and have been drinking it ever since. I love coffee, drink 3 cups a day now, I also like all forms of chocolate and like mild white wines. I never drink dark roast, can't take that burnt taste.

cayugafalls

(5,645 posts)
12. I roast my own coffee. I have mastered multiple pour over techniques. Coffee is only bitter...
Sun Dec 19, 2021, 02:11 AM
Dec 2021

if you suck at roasting and brewing coffee.

I can brew a cup of Ethiopian or Guatemalan that has no bitterness whatsoever, is sweet on the palate, with hints of mild chocolate, raspberry and a juicy mouth feel.

While I agree with the study and how it shows that people who are addicted to a substance will endure the pain of a bitter or sad cup of coffee in order to get their fix, that study does not, in any way shine a light on why millions of true coffee fans drink specialty coffee, roast their own beans and strive to pull the perfect shot of espresso.

Just the opinions of this one coffee aficionado...

PoindexterOglethorpe

(25,902 posts)
13. Interesting.
Sun Dec 19, 2021, 02:20 AM
Dec 2021

I drink coffee, but it absolutely must have cream and sugar. I can drink coffee with cream but no sugar, but absolutely cannot drink it without cream, even if sugar is available. Basic black, forget it.

Honestly, coffee is a completely different beverage with and without cream and/or sugar.

 

Manifestor_of_Light

(21,046 posts)
20. Yes, it must have cream and sugar.
Sun Dec 19, 2021, 05:33 AM
Dec 2021

I am a super taster. Super tasters don't like sour or bitter tastes.

I've always been a picky eater and I got yelled at a lot at the dinner table for not eating Grandma's boiled-to-death veggies and bitter greens. I have some major food allergies too. None of that shaming did anything to change me. They've all been dead for decades now. I eat lots of boring food.

PatrickforB

(14,592 posts)
15. I really like coffee, but I do use a little sweetener (usually a squirt of Stevia), and half
Sun Dec 19, 2021, 02:30 AM
Dec 2021

and half. But I love the taste of coffee, and the smell of it. And I like the way it feels waking me up in the morning.

Yeah, I guess I could do without it, and have done in past from time to time, but I really like to have maybe four or six cups in the morning.

deurbano

(2,895 posts)
16. I think I'm an exception to this. I would LIKE the psycho-stimulant effects, if I could get
Sun Dec 19, 2021, 02:31 AM
Dec 2021

over the bitter taste. I buy caffeinated water in order to avoid Diet Coke, which I used to drink too much of, and I drink tea sweetened with stevia, and I like dark chocolate, as long as it's no higher than 50%. I just don't like bitter. I can't stand beer or hard liquor (except in cocktails that hide the taste) and I don't actually like the taste of wine, either, but I trained myself to drink it to get the effect! (My main requirement in choosing a "favorite" wine is that I shudder as little as possible.) With coffee, I was just never motivated enough to get over the taste, since there are other sources of caffeine that taste better to me.

GReedDiamond

(5,316 posts)
17. I love coffee, the more caffeine, the better, but...
Sun Dec 19, 2021, 02:39 AM
Dec 2021

...I had to stop caffeinated beverages, esp coffee, prolly 10 years ago or so.

I was getting weird muscle twitches in various body places that I could only attribute to the high caffeine levels I was consuming...6 cups of the highest caffeine-level dark roast every morning, within 90 minutes, with more later.

If you've ever had electrical stimulation on your arms or whatever (which I have after a car crash not my fault) - that's kinda what it felt like, from the caffeine, just not continuously.

Once I stopped caffeinated coffee, and went to decaf green tea, the muscle twitches stopped.

Now it is hard to stay up so latte.


Mr.Bill

(24,330 posts)
18. The older I get the less I sweeten my coffee.
Sun Dec 19, 2021, 02:47 AM
Dec 2021

My current recipe is five parts strong Peete's coffee and one part chocolate milk. I like chocolate, and it has enough sweetness so no additional sugar is needed in the coffee. It's actually not a bad version of an expensive coffee shop Mocha. Probably costs me less than 25 cents to make at home with a $20 Mr Coffee drip maker. I have never understood people who pay $5 for a cup of coffee.

NBachers

(17,142 posts)
19. Primitive coffee-Grind dark beans, put in pitcher. Heat water, dump into grind. Filter after minutes
Sun Dec 19, 2021, 02:58 AM
Dec 2021

It probably breaks every aficionado law there is, and you can almost stand a fork up in it, but I love it. Inhaling the fresh ground beans is another olfactory thrill every time. I've been using the same no-paper gold coffee strainer for years and years.



murielm99

(30,765 posts)
21. I drink coffee, black.
Sun Dec 19, 2021, 05:53 AM
Dec 2021

I like strong coffee, and medium strong coffee.

I don't like dark chocolate. I seldom eat the other kind of chocolate as well. It doesn't appeal to me that much.

littlemissmartypants

(22,816 posts)
25. I love black coffee.
Sun Dec 19, 2021, 03:29 PM
Dec 2021

Nothing better on a cold morning than the smell and the feel of the mug in my cold hands. I savor the aroma and crave the taste. The first sip is like heaven.

I have also been known to drop a high cocoa percentage Ghirardelli dark chocolate square in a mug of that very same beverage. The thick chocolate slurry is addictive.

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