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left-of-center2012

(34,195 posts)
Tue Oct 12, 2021, 10:38 AM Oct 2021

This message was self-deleted by its author

This message was self-deleted by its author (left-of-center2012) on Sun Oct 17, 2021, 08:55 AM. When the original post in a discussion thread is self-deleted, the entire discussion thread is automatically locked so new replies cannot be posted.

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This message was self-deleted by its author (Original Post) left-of-center2012 Oct 2021 OP
there's a theory that these holdover genes are at the root of autoimmune disease. mopinko Oct 2021 #1
That's an interesting theory that I'd heard before wackadoo wabbit Oct 2021 #3
7000 years is not that long ago, as these things go. Scrivener7 Oct 2021 #2
That was my thought, too. wnylib Oct 2021 #4
These other humans fascinate me. When I did 23 and me, we found that we have Scrivener7 Oct 2021 #5
They fascinate me, too. wnylib Oct 2021 #6
I do have allergies, but no asthma. Scrivener7 Oct 2021 #7
Supposedly, according to some articles that I've read, wnylib Oct 2021 #8
Wow. That's pretty cool. Scrivener7 Oct 2021 #9
That's why I suspect that I have a lot of wnylib Oct 2021 #10

mopinko

(70,135 posts)
1. there's a theory that these holdover genes are at the root of autoimmune disease.
Tue Oct 12, 2021, 11:41 AM
Oct 2021

in my family there is a pretty clear correlation between ai and ginger.
it would account for the high correlation of some ai diseases w ethnicity. there are likely other absorbed ancestors out there to be found. there almost has to be.

it makes sense that a lot of these holdovers could be related to immunities or advantages in disease fighting. major driver of evolution. and it's all well and good until a modern human wakes them up. activated by immune stressors like viruses or pregnancies, the body suddenly notices they are there. foreign genes.

or at least, that's my impression of the theory. but it's very early research.

wackadoo wabbit

(1,167 posts)
3. That's an interesting theory that I'd heard before
Tue Oct 12, 2021, 07:05 PM
Oct 2021

It does make a certain amount of sense. Thanks for sharing it!

Scrivener7

(50,955 posts)
2. 7000 years is not that long ago, as these things go.
Tue Oct 12, 2021, 11:50 AM
Oct 2021

wnylib

(21,497 posts)
4. That was my thought, too.
Wed Oct 13, 2021, 08:37 AM
Oct 2021

Maybe they were able to survive into more recent times due to location.

Scrivener7

(50,955 posts)
5. These other humans fascinate me. When I did 23 and me, we found that we have
Wed Oct 13, 2021, 08:42 AM
Oct 2021

just about the maximum of what is left of Neanderthal in our DNA.

Lots of family jokes about that.

wnylib

(21,497 posts)
6. They fascinate me, too.
Wed Oct 13, 2021, 08:58 AM
Oct 2021

There were many more genome variations in the past than we ever guessed before DNA studies were possible.

I have not yet had my own DNA tested. I suspect that there is a lot of Neanderthal DNA in my genetic makeup, too. Just curious - Do you have any allergy or asthma problems? I have read studies that associate some Neanderthal DNA mutations with people who have multiple allergies and asthma.

Scrivener7

(50,955 posts)
7. I do have allergies, but no asthma.
Wed Oct 13, 2021, 09:03 AM
Oct 2021

wnylib

(21,497 posts)
8. Supposedly, according to some articles that I've read,
Wed Oct 13, 2021, 09:40 AM
Oct 2021

there are Neanderthal mutations that were beneficial to modern humans in fighting diseases that helped us to survive when our ancestors intermated, but those same mutations are thought to be responsible for causing some modern people to have multiple allergies.

Scrivener7

(50,955 posts)
9. Wow. That's pretty cool.
Wed Oct 13, 2021, 09:47 AM
Oct 2021

wnylib

(21,497 posts)
10. That's why I suspect that I have a lot of
Wed Oct 13, 2021, 09:53 AM
Oct 2021

Neanderthal DNA. Since my mother also had multiple allergies, I suspect that she was the Neanderthal culprit in my family.

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